Eating disorders in weight-related therapy (EDIT): Protocol for a systematic review with individual participant data meta-analysis of eating disorder risk in behavioural weight management

The Eating Disorders In weight-related Therapy (EDIT) Collaboration brings together data from randomised controlled trials of behavioural weight management interventions to identify individual participant risk factors and intervention strategies that contribute to eating disorder risk. We present a...

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Veröffentlicht in:PloS one 2023-07, Vol.18 (7), p.e0282401
Hauptverfasser: Jebeile, Hiba, Lister, Natalie B, Libesman, Sol, Hunter, Kylie E, McMaster, Caitlin M, Johnson, Brittany J, Baur, Louise A, Paxton, Susan J, Garnett, Sarah P, Ahern, Amy L, Wilfley, Denise E, Maguire, Sarah, Sainsbury, Amanda, Steinbeck, Katharine, Askie, Lisa, Braet, Caroline, Hill, Andrew J, Nicholls, Dasha, Jones, Rebecca A, Dammery, Genevieve, Grunseit, Alicia M, Cooper, Kelly, Kyle, Theodore K, Heeren, Faith A, Quigley, Fiona, Barnes, Rachel D, Bean, Melanie K, Beaulieu, Kristine, Bonham, Maxine, Boutelle, Kerri N, Branco, Braulio Henrique Magnani, Calugi, Simona, Cardel, Michelle I, Carpenter, Kelly, Cheng, Hoi Lun, Dalle Grave, Riccardo, Danielsen, Yngvild S, Demarzo, Marcelo, Dordevic, Aimee, Eichen, Dawn M, Goldschmidt, Andrea B, Hilbert, Anja, Houben, Katrijn, Lofrano do Prado, Mara, Martin, Corby K, McTiernan, Anne, Mensinger, Janell L, Pacanowski, Carly, do Prado, Wagner Luiz, Ramalho, Sofia M, Raynor, Hollie A, Rieger, Elizabeth, Robinson, Eric, Salvo, Vera, Sherwood, Nancy E, Simpson, Sharon A, Skjakodegard, Hanna F, Smith, Evelyn, Partridge, Stephanie, Tanofsky-Kraff, Marian, Taylor, Rachael W, Van Eyck, Annelies, Varady, Krista A, Vidmar, Alaina P, Whitelock, Victoria, Yanovski, Jack, Seidler, Anna L
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container_title PloS one
container_volume 18
creator Jebeile, Hiba
Lister, Natalie B
Libesman, Sol
Hunter, Kylie E
McMaster, Caitlin M
Johnson, Brittany J
Baur, Louise A
Paxton, Susan J
Garnett, Sarah P
Ahern, Amy L
Wilfley, Denise E
Maguire, Sarah
Sainsbury, Amanda
Steinbeck, Katharine
Askie, Lisa
Braet, Caroline
Hill, Andrew J
Nicholls, Dasha
Jones, Rebecca A
Dammery, Genevieve
Grunseit, Alicia M
Cooper, Kelly
Kyle, Theodore K
Heeren, Faith A
Quigley, Fiona
Barnes, Rachel D
Bean, Melanie K
Beaulieu, Kristine
Bonham, Maxine
Boutelle, Kerri N
Branco, Braulio Henrique Magnani
Calugi, Simona
Cardel, Michelle I
Carpenter, Kelly
Cheng, Hoi Lun
Dalle Grave, Riccardo
Danielsen, Yngvild S
Demarzo, Marcelo
Dordevic, Aimee
Eichen, Dawn M
Goldschmidt, Andrea B
Hilbert, Anja
Houben, Katrijn
Lofrano do Prado, Mara
Martin, Corby K
McTiernan, Anne
Mensinger, Janell L
Pacanowski, Carly
do Prado, Wagner Luiz
Ramalho, Sofia M
Raynor, Hollie A
Rieger, Elizabeth
Robinson, Eric
Salvo, Vera
Sherwood, Nancy E
Simpson, Sharon A
Skjakodegard, Hanna F
Smith, Evelyn
Partridge, Stephanie
Tanofsky-Kraff, Marian
Taylor, Rachael W
Van Eyck, Annelies
Varady, Krista A
Vidmar, Alaina P
Whitelock, Victoria
Yanovski, Jack
Seidler, Anna L
description The Eating Disorders In weight-related Therapy (EDIT) Collaboration brings together data from randomised controlled trials of behavioural weight management interventions to identify individual participant risk factors and intervention strategies that contribute to eating disorder risk. We present a protocol for a systematic review and individual participant data (IPD) meta-analysis which aims to identify participants at risk of developing eating disorders, or related symptoms, during or after weight management interventions conducted in adolescents or adults with overweight or obesity. We systematically searched four databases up to March 2022 and clinical trials registries to May 2022 to identify randomised controlled trials of weight management interventions conducted in adolescents or adults with overweight or obesity that measured eating disorder risk at pre- and post-intervention or follow-up. Authors from eligible trials have been invited to share their deidentified IPD. Two IPD meta-analyses will be conducted. The first IPD meta-analysis aims to examine participant level factors associated with a change in eating disorder scores during and following a weight management intervention. To do this we will examine baseline variables that predict change in eating disorder risk within intervention arms. The second IPD meta-analysis aims to assess whether there are participant level factors that predict whether participation in an intervention is more or less likely than no intervention to lead to a change in eating disorder risk. To do this, we will examine if there are differences in predictors of eating disorder risk between intervention and no-treatment control arms. The primary outcome will be a standardised mean difference in global eating disorder score from baseline to immediately post-intervention and at 6- and 12- months follow-up. Identifying participant level risk factors predicting eating disorder risk will inform screening and monitoring protocols to allow early identification and intervention for those at risk.
doi_str_mv 10.1371/journal.pone.0282401
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We present a protocol for a systematic review and individual participant data (IPD) meta-analysis which aims to identify participants at risk of developing eating disorders, or related symptoms, during or after weight management interventions conducted in adolescents or adults with overweight or obesity. We systematically searched four databases up to March 2022 and clinical trials registries to May 2022 to identify randomised controlled trials of weight management interventions conducted in adolescents or adults with overweight or obesity that measured eating disorder risk at pre- and post-intervention or follow-up. Authors from eligible trials have been invited to share their deidentified IPD. Two IPD meta-analyses will be conducted. The first IPD meta-analysis aims to examine participant level factors associated with a change in eating disorder scores during and following a weight management intervention. To do this we will examine baseline variables that predict change in eating disorder risk within intervention arms. The second IPD meta-analysis aims to assess whether there are participant level factors that predict whether participation in an intervention is more or less likely than no intervention to lead to a change in eating disorder risk. To do this, we will examine if there are differences in predictors of eating disorder risk between intervention and no-treatment control arms. The primary outcome will be a standardised mean difference in global eating disorder score from baseline to immediately post-intervention and at 6- and 12- months follow-up. Identifying participant level risk factors predicting eating disorder risk will inform screening and monitoring protocols to allow early identification and intervention for those at risk.</description><identifier>ISSN: 1932-6203</identifier><identifier>EISSN: 1932-6203</identifier><identifier>DOI: 10.1371/journal.pone.0282401</identifier><identifier>PMID: 37428754</identifier><language>eng</language><publisher>United States: Public Library of Science</publisher><subject>Adolescent ; Adolescents ; Adult ; Adults ; Behavior ; Behavior Therapy ; Binge eating ; Biology and Life Sciences ; Body mass index ; Body weight ; Care and treatment ; Clinical trials ; Collaboration ; Complications and side effects ; Computer and Information Sciences ; Data analysis ; Diabetes ; Eating disorders ; Feeding and Eating Disorders - therapy ; Gastrointestinal surgery ; Health aspects ; Health risks ; Humans ; Intervention ; Medicine and Health Sciences ; Meta-analysis ; Meta-Analysis as Topic ; Obesity ; Obesity in adolescence ; Overweight ; Overweight - complications ; Overweight - therapy ; Physical Sciences ; Prevention ; Questionnaires ; Research and Analysis Methods ; Risk factors ; Risk taking ; Signs and symptoms ; Sleep ; Study Protocol ; Systematic review ; Systematic Reviews as Topic ; Teenagers ; Weight control ; Weight loss</subject><ispartof>PloS one, 2023-07, Vol.18 (7), p.e0282401</ispartof><rights>Copyright: © 2023 Jebeile et al. 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K</creatorcontrib><creatorcontrib>McTiernan, Anne</creatorcontrib><creatorcontrib>Mensinger, Janell L</creatorcontrib><creatorcontrib>Pacanowski, Carly</creatorcontrib><creatorcontrib>do Prado, Wagner Luiz</creatorcontrib><creatorcontrib>Ramalho, Sofia M</creatorcontrib><creatorcontrib>Raynor, Hollie A</creatorcontrib><creatorcontrib>Rieger, Elizabeth</creatorcontrib><creatorcontrib>Robinson, Eric</creatorcontrib><creatorcontrib>Salvo, Vera</creatorcontrib><creatorcontrib>Sherwood, Nancy E</creatorcontrib><creatorcontrib>Simpson, Sharon A</creatorcontrib><creatorcontrib>Skjakodegard, Hanna F</creatorcontrib><creatorcontrib>Smith, Evelyn</creatorcontrib><creatorcontrib>Partridge, Stephanie</creatorcontrib><creatorcontrib>Tanofsky-Kraff, Marian</creatorcontrib><creatorcontrib>Taylor, Rachael W</creatorcontrib><creatorcontrib>Van Eyck, Annelies</creatorcontrib><creatorcontrib>Varady, Krista A</creatorcontrib><creatorcontrib>Vidmar, Alaina P</creatorcontrib><creatorcontrib>Whitelock, Victoria</creatorcontrib><creatorcontrib>Yanovski, Jack</creatorcontrib><creatorcontrib>Seidler, Anna L</creatorcontrib><creatorcontrib>Eating Disorders In weight-related Therapy (EDIT) Collaboration</creatorcontrib><creatorcontrib>on behalf of the Eating Disorders In weight-related Therapy (EDIT) Collaboration</creatorcontrib><title>Eating disorders in weight-related therapy (EDIT): Protocol for a systematic review with individual participant data meta-analysis of eating disorder risk in behavioural weight management</title><title>PloS one</title><addtitle>PLoS One</addtitle><description>The Eating Disorders In weight-related Therapy (EDIT) Collaboration brings together data from randomised controlled trials of behavioural weight management interventions to identify individual participant risk factors and intervention strategies that contribute to eating disorder risk. We present a protocol for a systematic review and individual participant data (IPD) meta-analysis which aims to identify participants at risk of developing eating disorders, or related symptoms, during or after weight management interventions conducted in adolescents or adults with overweight or obesity. We systematically searched four databases up to March 2022 and clinical trials registries to May 2022 to identify randomised controlled trials of weight management interventions conducted in adolescents or adults with overweight or obesity that measured eating disorder risk at pre- and post-intervention or follow-up. Authors from eligible trials have been invited to share their deidentified IPD. Two IPD meta-analyses will be conducted. The first IPD meta-analysis aims to examine participant level factors associated with a change in eating disorder scores during and following a weight management intervention. To do this we will examine baseline variables that predict change in eating disorder risk within intervention arms. The second IPD meta-analysis aims to assess whether there are participant level factors that predict whether participation in an intervention is more or less likely than no intervention to lead to a change in eating disorder risk. To do this, we will examine if there are differences in predictors of eating disorder risk between intervention and no-treatment control arms. The primary outcome will be a standardised mean difference in global eating disorder score from baseline to immediately post-intervention and at 6- and 12- months follow-up. Identifying participant level risk factors predicting eating disorder risk will inform screening and monitoring protocols to allow early identification and intervention for those at risk.</description><subject>Adolescent</subject><subject>Adolescents</subject><subject>Adult</subject><subject>Adults</subject><subject>Behavior</subject><subject>Behavior Therapy</subject><subject>Binge eating</subject><subject>Biology and Life Sciences</subject><subject>Body mass index</subject><subject>Body weight</subject><subject>Care and treatment</subject><subject>Clinical trials</subject><subject>Collaboration</subject><subject>Complications and side effects</subject><subject>Computer and Information Sciences</subject><subject>Data analysis</subject><subject>Diabetes</subject><subject>Eating disorders</subject><subject>Feeding and Eating Disorders - therapy</subject><subject>Gastrointestinal surgery</subject><subject>Health aspects</subject><subject>Health risks</subject><subject>Humans</subject><subject>Intervention</subject><subject>Medicine and Health Sciences</subject><subject>Meta-analysis</subject><subject>Meta-Analysis as Topic</subject><subject>Obesity</subject><subject>Obesity in adolescence</subject><subject>Overweight</subject><subject>Overweight - complications</subject><subject>Overweight - therapy</subject><subject>Physical Sciences</subject><subject>Prevention</subject><subject>Questionnaires</subject><subject>Research and Analysis Methods</subject><subject>Risk factors</subject><subject>Risk taking</subject><subject>Signs and symptoms</subject><subject>Sleep</subject><subject>Study Protocol</subject><subject>Systematic review</subject><subject>Systematic Reviews as Topic</subject><subject>Teenagers</subject><subject>Weight control</subject><subject>Weight 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disorders in weight-related therapy (EDIT): Protocol for a systematic review with individual participant data meta-analysis of eating disorder risk in behavioural weight management</title><author>Jebeile, Hiba ; Lister, Natalie B ; Libesman, Sol ; Hunter, Kylie E ; McMaster, Caitlin M ; Johnson, Brittany J ; Baur, Louise A ; Paxton, Susan J ; Garnett, Sarah P ; Ahern, Amy L ; Wilfley, Denise E ; Maguire, Sarah ; Sainsbury, Amanda ; Steinbeck, Katharine ; Askie, Lisa ; Braet, Caroline ; Hill, Andrew J ; Nicholls, Dasha ; Jones, Rebecca A ; Dammery, Genevieve ; Grunseit, Alicia M ; Cooper, Kelly ; Kyle, Theodore K ; Heeren, Faith A ; Quigley, Fiona ; Barnes, Rachel D ; Bean, Melanie K ; Beaulieu, Kristine ; Bonham, Maxine ; Boutelle, Kerri N ; Branco, Braulio Henrique Magnani ; Calugi, Simona ; Cardel, Michelle I ; Carpenter, Kelly ; Cheng, Hoi Lun ; Dalle Grave, Riccardo ; Danielsen, Yngvild S ; Demarzo, Marcelo ; Dordevic, Aimee ; Eichen, Dawn M ; Goldschmidt, Andrea B ; Hilbert, Anja ; Houben, Katrijn ; Lofrano do Prado, Mara ; Martin, Corby K ; McTiernan, Anne ; Mensinger, Janell L ; Pacanowski, Carly ; do Prado, Wagner Luiz ; Ramalho, Sofia M ; Raynor, Hollie A ; Rieger, Elizabeth ; Robinson, Eric ; Salvo, Vera ; Sherwood, Nancy E ; Simpson, Sharon A ; Skjakodegard, Hanna F ; Smith, Evelyn ; Partridge, Stephanie ; Tanofsky-Kraff, Marian ; Taylor, Rachael W ; Van Eyck, Annelies ; Varady, Krista A ; Vidmar, Alaina P ; Whitelock, Victoria ; Yanovski, Jack ; Seidler, Anna L</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c543t-d101bbd6dc738a2ff5bb88eecdd481342a3af65192ed535fbd11fd506610b5093</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><topic>Adolescent</topic><topic>Adolescents</topic><topic>Adult</topic><topic>Adults</topic><topic>Behavior</topic><topic>Behavior Therapy</topic><topic>Binge eating</topic><topic>Biology and Life Sciences</topic><topic>Body mass index</topic><topic>Body weight</topic><topic>Care and treatment</topic><topic>Clinical trials</topic><topic>Collaboration</topic><topic>Complications and side effects</topic><topic>Computer and Information Sciences</topic><topic>Data analysis</topic><topic>Diabetes</topic><topic>Eating disorders</topic><topic>Feeding and Eating Disorders - therapy</topic><topic>Gastrointestinal surgery</topic><topic>Health aspects</topic><topic>Health risks</topic><topic>Humans</topic><topic>Intervention</topic><topic>Medicine and Health Sciences</topic><topic>Meta-analysis</topic><topic>Meta-Analysis as Topic</topic><topic>Obesity</topic><topic>Obesity in adolescence</topic><topic>Overweight</topic><topic>Overweight - complications</topic><topic>Overweight - therapy</topic><topic>Physical Sciences</topic><topic>Prevention</topic><topic>Questionnaires</topic><topic>Research and Analysis Methods</topic><topic>Risk factors</topic><topic>Risk taking</topic><topic>Signs and symptoms</topic><topic>Sleep</topic><topic>Study Protocol</topic><topic>Systematic review</topic><topic>Systematic Reviews as Topic</topic><topic>Teenagers</topic><topic>Weight control</topic><topic>Weight loss</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Jebeile, Hiba</creatorcontrib><creatorcontrib>Lister, Natalie B</creatorcontrib><creatorcontrib>Libesman, Sol</creatorcontrib><creatorcontrib>Hunter, Kylie E</creatorcontrib><creatorcontrib>McMaster, Caitlin M</creatorcontrib><creatorcontrib>Johnson, Brittany J</creatorcontrib><creatorcontrib>Baur, Louise A</creatorcontrib><creatorcontrib>Paxton, Susan J</creatorcontrib><creatorcontrib>Garnett, Sarah P</creatorcontrib><creatorcontrib>Ahern, Amy L</creatorcontrib><creatorcontrib>Wilfley, Denise E</creatorcontrib><creatorcontrib>Maguire, Sarah</creatorcontrib><creatorcontrib>Sainsbury, Amanda</creatorcontrib><creatorcontrib>Steinbeck, Katharine</creatorcontrib><creatorcontrib>Askie, Lisa</creatorcontrib><creatorcontrib>Braet, Caroline</creatorcontrib><creatorcontrib>Hill, Andrew J</creatorcontrib><creatorcontrib>Nicholls, Dasha</creatorcontrib><creatorcontrib>Jones, Rebecca A</creatorcontrib><creatorcontrib>Dammery, Genevieve</creatorcontrib><creatorcontrib>Grunseit, Alicia M</creatorcontrib><creatorcontrib>Cooper, Kelly</creatorcontrib><creatorcontrib>Kyle, Theodore K</creatorcontrib><creatorcontrib>Heeren, Faith A</creatorcontrib><creatorcontrib>Quigley, Fiona</creatorcontrib><creatorcontrib>Barnes, Rachel D</creatorcontrib><creatorcontrib>Bean, Melanie K</creatorcontrib><creatorcontrib>Beaulieu, Kristine</creatorcontrib><creatorcontrib>Bonham, Maxine</creatorcontrib><creatorcontrib>Boutelle, Kerri N</creatorcontrib><creatorcontrib>Branco, Braulio Henrique Magnani</creatorcontrib><creatorcontrib>Calugi, Simona</creatorcontrib><creatorcontrib>Cardel, Michelle I</creatorcontrib><creatorcontrib>Carpenter, Kelly</creatorcontrib><creatorcontrib>Cheng, Hoi Lun</creatorcontrib><creatorcontrib>Dalle Grave, Riccardo</creatorcontrib><creatorcontrib>Danielsen, Yngvild S</creatorcontrib><creatorcontrib>Demarzo, Marcelo</creatorcontrib><creatorcontrib>Dordevic, Aimee</creatorcontrib><creatorcontrib>Eichen, Dawn M</creatorcontrib><creatorcontrib>Goldschmidt, Andrea B</creatorcontrib><creatorcontrib>Hilbert, Anja</creatorcontrib><creatorcontrib>Houben, Katrijn</creatorcontrib><creatorcontrib>Lofrano do Prado, Mara</creatorcontrib><creatorcontrib>Martin, Corby K</creatorcontrib><creatorcontrib>McTiernan, Anne</creatorcontrib><creatorcontrib>Mensinger, Janell L</creatorcontrib><creatorcontrib>Pacanowski, Carly</creatorcontrib><creatorcontrib>do Prado, Wagner Luiz</creatorcontrib><creatorcontrib>Ramalho, Sofia M</creatorcontrib><creatorcontrib>Raynor, Hollie A</creatorcontrib><creatorcontrib>Rieger, Elizabeth</creatorcontrib><creatorcontrib>Robinson, Eric</creatorcontrib><creatorcontrib>Salvo, Vera</creatorcontrib><creatorcontrib>Sherwood, Nancy E</creatorcontrib><creatorcontrib>Simpson, Sharon A</creatorcontrib><creatorcontrib>Skjakodegard, Hanna F</creatorcontrib><creatorcontrib>Smith, Evelyn</creatorcontrib><creatorcontrib>Partridge, Stephanie</creatorcontrib><creatorcontrib>Tanofsky-Kraff, Marian</creatorcontrib><creatorcontrib>Taylor, Rachael W</creatorcontrib><creatorcontrib>Van Eyck, Annelies</creatorcontrib><creatorcontrib>Varady, Krista A</creatorcontrib><creatorcontrib>Vidmar, Alaina P</creatorcontrib><creatorcontrib>Whitelock, Victoria</creatorcontrib><creatorcontrib>Yanovski, Jack</creatorcontrib><creatorcontrib>Seidler, Anna L</creatorcontrib><creatorcontrib>Eating Disorders In weight-related Therapy (EDIT) Collaboration</creatorcontrib><creatorcontrib>on behalf of the Eating Disorders In weight-related Therapy (EDIT) Collaboration</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE 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J</au><au>Nicholls, Dasha</au><au>Jones, Rebecca A</au><au>Dammery, Genevieve</au><au>Grunseit, Alicia M</au><au>Cooper, Kelly</au><au>Kyle, Theodore K</au><au>Heeren, Faith A</au><au>Quigley, Fiona</au><au>Barnes, Rachel D</au><au>Bean, Melanie K</au><au>Beaulieu, Kristine</au><au>Bonham, Maxine</au><au>Boutelle, Kerri N</au><au>Branco, Braulio Henrique Magnani</au><au>Calugi, Simona</au><au>Cardel, Michelle I</au><au>Carpenter, Kelly</au><au>Cheng, Hoi Lun</au><au>Dalle Grave, Riccardo</au><au>Danielsen, Yngvild S</au><au>Demarzo, Marcelo</au><au>Dordevic, Aimee</au><au>Eichen, Dawn M</au><au>Goldschmidt, Andrea B</au><au>Hilbert, Anja</au><au>Houben, Katrijn</au><au>Lofrano do Prado, Mara</au><au>Martin, Corby K</au><au>McTiernan, Anne</au><au>Mensinger, Janell L</au><au>Pacanowski, Carly</au><au>do Prado, Wagner Luiz</au><au>Ramalho, Sofia M</au><au>Raynor, Hollie A</au><au>Rieger, Elizabeth</au><au>Robinson, Eric</au><au>Salvo, Vera</au><au>Sherwood, Nancy E</au><au>Simpson, Sharon A</au><au>Skjakodegard, Hanna F</au><au>Smith, Evelyn</au><au>Partridge, Stephanie</au><au>Tanofsky-Kraff, Marian</au><au>Taylor, Rachael W</au><au>Van Eyck, Annelies</au><au>Varady, Krista A</au><au>Vidmar, Alaina P</au><au>Whitelock, Victoria</au><au>Yanovski, Jack</au><au>Seidler, Anna L</au><aucorp>Eating Disorders In weight-related Therapy (EDIT) Collaboration</aucorp><aucorp>on behalf of the Eating Disorders In weight-related Therapy (EDIT) Collaboration</aucorp><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Eating disorders in weight-related therapy (EDIT): Protocol for a systematic review with individual participant data meta-analysis of eating disorder risk in behavioural weight management</atitle><jtitle>PloS one</jtitle><addtitle>PLoS One</addtitle><date>2023-07-10</date><risdate>2023</risdate><volume>18</volume><issue>7</issue><spage>e0282401</spage><pages>e0282401-</pages><issn>1932-6203</issn><eissn>1932-6203</eissn><abstract>The Eating Disorders In weight-related Therapy (EDIT) Collaboration brings together data from randomised controlled trials of behavioural weight management interventions to identify individual participant risk factors and intervention strategies that contribute to eating disorder risk. We present a protocol for a systematic review and individual participant data (IPD) meta-analysis which aims to identify participants at risk of developing eating disorders, or related symptoms, during or after weight management interventions conducted in adolescents or adults with overweight or obesity. We systematically searched four databases up to March 2022 and clinical trials registries to May 2022 to identify randomised controlled trials of weight management interventions conducted in adolescents or adults with overweight or obesity that measured eating disorder risk at pre- and post-intervention or follow-up. Authors from eligible trials have been invited to share their deidentified IPD. Two IPD meta-analyses will be conducted. The first IPD meta-analysis aims to examine participant level factors associated with a change in eating disorder scores during and following a weight management intervention. To do this we will examine baseline variables that predict change in eating disorder risk within intervention arms. The second IPD meta-analysis aims to assess whether there are participant level factors that predict whether participation in an intervention is more or less likely than no intervention to lead to a change in eating disorder risk. To do this, we will examine if there are differences in predictors of eating disorder risk between intervention and no-treatment control arms. The primary outcome will be a standardised mean difference in global eating disorder score from baseline to immediately post-intervention and at 6- and 12- months follow-up. Identifying participant level risk factors predicting eating disorder risk will inform screening and monitoring protocols to allow early identification and intervention for those at risk.</abstract><cop>United States</cop><pub>Public Library of Science</pub><pmid>37428754</pmid><doi>10.1371/journal.pone.0282401</doi><orcidid>https://orcid.org/0000-0002-7447-1839</orcidid><orcidid>https://orcid.org/0000-0002-6340-7348</orcidid><orcidid>https://orcid.org/0000-0001-8926-6953</orcidid><orcidid>https://orcid.org/0000-0003-4722-969X</orcidid><orcidid>https://orcid.org/0000-0002-2144-9195</orcidid><orcidid>https://orcid.org/0000-0002-0405-3164</orcidid><orcidid>https://orcid.org/0000-0002-8125-4015</orcidid><orcidid>https://orcid.org/0000-0003-2197-1175</orcidid><orcidid>https://orcid.org/0000-0001-7552-0789</orcidid><orcidid>https://orcid.org/0000-0002-8296-3024</orcidid><orcidid>https://orcid.org/0000-0003-1782-8122</orcidid><orcidid>https://orcid.org/0000-0002-2796-9220</orcidid><orcidid>https://orcid.org/0000-0002-8188-712X</orcidid><oa>free_for_read</oa></addata></record>
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subjects Adolescent
Adolescents
Adult
Adults
Behavior
Behavior Therapy
Binge eating
Biology and Life Sciences
Body mass index
Body weight
Care and treatment
Clinical trials
Collaboration
Complications and side effects
Computer and Information Sciences
Data analysis
Diabetes
Eating disorders
Feeding and Eating Disorders - therapy
Gastrointestinal surgery
Health aspects
Health risks
Humans
Intervention
Medicine and Health Sciences
Meta-analysis
Meta-Analysis as Topic
Obesity
Obesity in adolescence
Overweight
Overweight - complications
Overweight - therapy
Physical Sciences
Prevention
Questionnaires
Research and Analysis Methods
Risk factors
Risk taking
Signs and symptoms
Sleep
Study Protocol
Systematic review
Systematic Reviews as Topic
Teenagers
Weight control
Weight loss
title Eating disorders in weight-related therapy (EDIT): Protocol for a systematic review with individual participant data meta-analysis of eating disorder risk in behavioural weight management
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