Capsular polysaccharide inhibits vaccine-induced O-antigen antibody binding and function across both classical and hypervirulent K2:O1 strains of Klebsiella pneumoniae

Klebsiella pneumoniae presents as two circulating pathotypes: classical K. pneumoniae (cKp) and hypervirulent K. pneumoniae (hvKp). Classical isolates are considered urgent threats due to their antibiotic resistance profiles, while hvKp isolates have historically been antibiotic susceptible. Recentl...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	PLoS pathogens 2023-05, Vol.19 (5), p.e1011367-e1011367
Hauptverfasser:	Wantuch, Paeton L, Knoot, Cory J, Robinson, Lloyd S, Vinogradov, Evgeny, Scott, Nichollas E, Harding, Christian M, Rosen, David A
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Animal models Animals Anti-Bacterial Agents - pharmacology Antibiotic resistance Antibiotics Antibodies Antigen-antibody complexes Antigens Bacterial pneumonia Binding Biology and Life Sciences Capsular polysaccharides Cloning Conjugate vaccines Control Dosage and administration Drug resistance in microorganisms E coli Gene loci Health aspects Immunogenicity Immunotherapy Infections Klebsiella Klebsiella Infections - prevention & control Klebsiella pneumoniae Lipopolysaccharides Lipopolysaccharides - metabolism Medical research Medicine and Health Sciences Medicine, Experimental Mice NMR Nuclear magnetic resonance O Antigens Pathogens Physiological aspects Pneumonia Polymers Polysaccharides Proteins Research and Analysis Methods Saccharides Testing Vaccines Virulence
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!