Systems biology elucidates the distinctive metabolic niche filled by the human gut microbe Eggerthella lenta

Human gut bacteria perform diverse metabolic functions with consequences for host health. The prevalent and disease-linked Actinobacterium Eggerthella lenta performs several unusual chemical transformations, but it does not metabolize sugars and its core growth strategy remains unclear. To obtain a...

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Veröffentlicht in:	PLoS biology 2023-05, Vol.21 (5), p.e3002125
Hauptverfasser:	Noecker, Cecilia, Sanchez, Juan, Bisanz, Jordan E, Escalante, Veronica, Alexander, Margaret, Trepka, Kai, Heinken, Almut, Liu, Yuanyuan, Dodd, Dylan, Thiele, Ines, DeFelice, Brian C, Turnbaugh, Peter J
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetic acid Actinobacteria - metabolism Agmatine Alternative energy sources Amino acids Animals Bacteria Biology Biology and Life Sciences Carbon sources Catabolism Community Culture media Dopamine Ecosystem Eggerthella lenta Gastrointestinal Microbiome Genomes Gnotobiotic Gram-positive bacteria Human performance Humans Medicine and Health Sciences Metabolic networks Metabolism Metabolites Metabolomics Methods and Resources Mice Microbiota Microbiota (Symbiotic organisms) Microorganisms Niches Physical Sciences Physiological aspects Physiological research Research and Analysis Methods Stable isotopes Systems Biology
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