Heat shock protein 70 protects the lungs from hyperoxic injury in a neonatal rat model of bronchopulmonary dysplasia

Hyperoxia plays a significant role in the pathogenesis of lung injury, such as bronchopulmonary dysplasia (BPD), in premature infants or newborns. BPD management aims to minimize further injury, provide an optimal environment to support growth and recovery. In clinic neonatal care, we need a new the...

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Veröffentlicht in:	PloS one 2023-05, Vol.18 (5), p.e0285944-e0285944
Hauptverfasser:	Lee, Cheng-Han, Su, Tzu-Cheng, Lee, Ming-Sheng, Hsu, Chien-Sheng, Yang, Rei-Cheng, Kao, Jun-Kai
Format:	Artikel
Sprache:	eng
Schlagworte:	Alveoli Animal models Animals Animals, Newborn Antibodies Apoptosis Biology and Life Sciences Bronchopulmonary dysplasia Bronchopulmonary Dysplasia - complications Bronchopulmonary Dysplasia - prevention & control Disease Models, Animal Dysplasia Health aspects Heat Heat shock proteins Heat stress Heat tolerance HSP70 Heat-Shock Proteins - metabolism Hsp70 protein Humans Hyperoxia Hyperoxia - metabolism Infant, Newborn Infants (Premature) Inflammation Injury prevention Laboratory animals Lung - pathology Lung diseases Lung Injury - etiology Lung Injury - metabolism Lung Injury - prevention & control Lungs Macrophages Medicine and Health Sciences Morphology Neonates Newborn babies Oxygen Pathogenesis Physical Sciences Premature babies Premature birth Proteins Rats Rats, Wistar Risk reduction Room temperature Superoxide Survival
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