Gre factors help Salmonella adapt to oxidative stress by improving transcription elongation and fidelity of metabolic genes

Detoxification, scavenging, and repair systems embody the archetypical antioxidant defenses of prokaryotic and eukaryotic cells. Metabolic rewiring also aids with the adaptation of bacteria to oxidative stress. Evolutionarily diverse bacteria combat the toxicity of reactive oxygen species (ROS) by a...

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Veröffentlicht in:	PLoS biology 2023-04, Vol.21 (4), p.e3002051-e3002051
Hauptverfasser:	Kant, Sashi, Till, James Karl A, Liu, Lin, Margolis, Alyssa, Uppalapati, Siva, Kim, Ju-Sim, Vazquez-Torres, Andres
Format:	Artikel
Sprache:	eng
Schlagworte:	Accuracy Adaptation Aerobic respiration Amino acids Analysis Antimicrobial agents Antioxidants Bacteria Biology and Life Sciences Cytochrome Cytochrome bd Cytochromes Cytotoxicity Dehydrogenases Detoxification DksA protein DNA-directed RNA polymerase Elongation Fidelity Gene expression Genes Genetic aspects Genetic transcription Glucose Glucose - metabolism Glycolysis Identification and classification Medicine and Health Sciences Metabolic pathways Metabolism NAD(P)H oxidase NADPH Oxidases - metabolism Overflow Oxidase Oxidation resistance Oxidation-Reduction Oxidative stress Oxidative Stress - genetics Pathogenesis Physical Sciences Proteins Reactive oxygen species Respiration RNA polymerase RNA polymerases Salmonella Salmonella - genetics Scavenging Stringent response Toxicity Transcription elongation Transcription initiation Virulence
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