VSTM1-v2 does not drive human Th17 cell differentiation: A replication study

Signal inhibitory receptor on leukocytes-1 (SIRL-1) is an immune inhibitory receptor expressed on human myeloid cells. We previously showed that dendritic cell (DC)-driven Th17 cell differentiation of human naive CD4+ T cells requires presence of neutrophils, which is inhibited by SIRL-1 ligation. V...

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Veröffentlicht in:	PloS one 2023-04, Vol.18 (4), p.e0284404-e0284404
Hauptverfasser:	von Richthofen, Helen J, Hafkamp, Florianne M J, van Haperen, Anouk, de Jong, Esther C, Meyaard, Linde
Format:	Artikel
Sprache:	eng
Schlagworte:	Biology and Life Sciences CD4 antigen Cell Differentiation Cells Cytokines Dendritic Cells Differentiation (biology) Evaluation Flow cytometry Granulocytes Health aspects Helper cells Humans Leukocytes Leukocytes (neutrophilic) Lymphocytes Lymphocytes T Medicine and Health Sciences Myeloid cells Neutrophils Protein Isoforms Receptors Research and Analysis Methods T cells Th17 Cells
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