Evaluation of decellularization process for developing osteogenic bovine cancellous bone scaffolds in-vitro

Current immunological issues in bone grafting regarding the transfer of xenogeneic donor bone cells into the recipient are challenging the industry to produce safer acellular natural matrices for bone regeneration. The aim of this study was to investigate the efficacy of a novel decellularization te...

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Veröffentlicht in:	PloS one 2023-04, Vol.18 (4), p.e0283922
Hauptverfasser:	Al Qabbani, Ali, Rani, K G Aghila, Syarif, Junaidi, AlKawas, Sausan, Sheikh Abdul Hamid, Suzina, Samsudin, A R, Azlina, Ahmad
Format:	Artikel
Sprache:	eng
Schlagworte:	Acids Alcohol Alizarin Animals Biology and Life Sciences Biomedical engineering Bone (cancellous) Bone demineralization Bone grafts Bone growth Cancellous Bone Cattle Cell adhesion Cell Differentiation Cell proliferation Child, Preschool Collagen Collagens Demineralization Differentiation (biology) Electron microscopy Evaluation Extracellular matrix Fibrils Fourier transforms Gene expression Humans Immunology Infant Infrared spectroscopy Lipids Mechanical properties Mechanical tests Medicine and Health Sciences Methods Mineralization Nodules Nucleic Acids Osteoconduction Osteogenesis Osteogenesis - physiology Physiological aspects Protein seeding Regeneration Regeneration (physiology) Research and Analysis Methods Scaffolds Scanning electron microscopy Skin & tissue grafts Substitute bone Tissue Engineering - methods Tissue Scaffolds - chemistry Topography Trabecular bone X-ray spectroscopy Xenografts
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