Quantitative assessment of atelectasis formation under high frequency jet ventilation during liver tumour ablation-A computer tomography study
High frequency jet ventilation (HFJV) can be used to minimise sub-diaphragmal organ displacements. Treated patients are in a supine position, under general anaesthesia and fully muscle relaxed. These are factors that are known to contribute to the formation of atelectasis. The HFJV-catheter is inser...
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| Veröffentlicht in: | PloS one 2023-04, Vol.18 (4), p.e0282724 |
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| description | High frequency jet ventilation (HFJV) can be used to minimise sub-diaphragmal organ displacements. Treated patients are in a supine position, under general anaesthesia and fully muscle relaxed. These are factors that are known to contribute to the formation of atelectasis. The HFJV-catheter is inserted freely inside the endotracheal tube and the system is therefore open to atmospheric pressure.
The aim of this study was to assess the formation of atelectasis over time during HFJV in patients undergoing liver tumour ablation under general anaesthesia.
In this observational study twenty-five patients were studied. Repeated computed tomography (CT) scans were taken at the start of HFJV and every 15 minutes thereafter up until 45 minutes. From the CT images, four lung compartments were defined: hyperinflated, normoinflated, poorly inflated and atelectatic areas. The extension of each lung compartment was expressed as a percentage of the total lung area.
Atelectasis at 30 minutes, 7.9% (SD 3.5, p = 0.002) and at 45 minutes 8,1% (SD 5.2, p = 0.024), was significantly higher compared to baseline 5.6% (SD 2.5). The amount of normoinflated lung volumes were unchanged over the period studied. Only a few minor perioperative respiratory adverse events were noted.
Atelectasis during HFJV in stereotactic liver tumour ablation increased over the first 45 minutes but tended to stabilise with no impact on normoinflated lung volume. Using HFJV during stereotactic liver ablation is safe regarding formation of atelectasis. |
| doi_str_mv | 10.1371/journal.pone.0282724 |
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The aim of this study was to assess the formation of atelectasis over time during HFJV in patients undergoing liver tumour ablation under general anaesthesia.
In this observational study twenty-five patients were studied. Repeated computed tomography (CT) scans were taken at the start of HFJV and every 15 minutes thereafter up until 45 minutes. From the CT images, four lung compartments were defined: hyperinflated, normoinflated, poorly inflated and atelectatic areas. The extension of each lung compartment was expressed as a percentage of the total lung area.
Atelectasis at 30 minutes, 7.9% (SD 3.5, p = 0.002) and at 45 minutes 8,1% (SD 5.2, p = 0.024), was significantly higher compared to baseline 5.6% (SD 2.5). The amount of normoinflated lung volumes were unchanged over the period studied. Only a few minor perioperative respiratory adverse events were noted.
Atelectasis during HFJV in stereotactic liver tumour ablation increased over the first 45 minutes but tended to stabilise with no impact on normoinflated lung volume. Using HFJV during stereotactic liver ablation is safe regarding formation of atelectasis.</description><identifier>ISSN: 1932-6203</identifier><identifier>EISSN: 1932-6203</identifier><identifier>DOI: 10.1371/journal.pone.0282724</identifier><identifier>PMID: 37011083</identifier><language>eng</language><publisher>United States: Public Library of Science</publisher><subject>Ablation ; Ablation (Surgery) ; Anesthesia ; Atelectasis ; Atmospheric pressure ; Biology and Life Sciences ; Carbon dioxide ; Care and treatment ; Catheters ; Clinical medicine ; Complications and side effects ; Computed tomography ; General anesthesia ; High frequencies ; High-Frequency Jet Ventilation - adverse effects ; High-Frequency Jet Ventilation - methods ; Humans ; Intubation ; Liver ; Liver cancer ; Liver Neoplasms - diagnostic imaging ; Liver Neoplasms - surgery ; Lung cancer ; Lungs ; Mechanical ventilation ; Medical instruments ; Medicine and Health Sciences ; Observational studies ; Patient outcomes ; Patients ; Pulmonary Atelectasis - diagnostic imaging ; Pulmonary Atelectasis - etiology ; Radiation ; Research and Analysis Methods ; Respiration ; Supine position ; Surgery ; Tomography ; Tomography, X-Ray Computed ; Tumors ; Ventilation ; Ventilators</subject><ispartof>PloS one, 2023-04, Vol.18 (4), p.e0282724</ispartof><rights>Copyright: © 2023 Galmén et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.</rights><rights>COPYRIGHT 2023 Public Library of Science</rights><rights>2023 Galmén et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>2023 Galmén et al 2023 Galmén et al</rights><rights>2023 Galmén et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c628t-a54c65bda9c074e764f6eeec9242961331002ccfc60b68189c33029f0536db8e3</citedby><cites>FETCH-LOGICAL-c628t-a54c65bda9c074e764f6eeec9242961331002ccfc60b68189c33029f0536db8e3</cites><orcidid>0000-0002-4425-9044</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC10069764/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC10069764/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,550,723,776,780,860,881,2096,2915,23845,27901,27902,53766,53768,79569,79570</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/37011083$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink><backlink>$$Uhttps://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-506923$$DView record from Swedish Publication Index$$Hfree_for_read</backlink><backlink>$$Uhttp://kipublications.ki.se/Default.aspx?queryparsed=id:152922515$$DView record from Swedish Publication Index$$Hfree_for_read</backlink></links><search><creatorcontrib>Galmén, Karolina</creatorcontrib><creatorcontrib>Jakobsson, Jan G</creatorcontrib><creatorcontrib>Perchiazzi, Gaetano</creatorcontrib><creatorcontrib>Freedman, Jacob</creatorcontrib><creatorcontrib>Harbut, Piotr</creatorcontrib><title>Quantitative assessment of atelectasis formation under high frequency jet ventilation during liver tumour ablation-A computer tomography study</title><title>PloS one</title><addtitle>PLoS One</addtitle><description>High frequency jet ventilation (HFJV) can be used to minimise sub-diaphragmal organ displacements. Treated patients are in a supine position, under general anaesthesia and fully muscle relaxed. These are factors that are known to contribute to the formation of atelectasis. The HFJV-catheter is inserted freely inside the endotracheal tube and the system is therefore open to atmospheric pressure.
The aim of this study was to assess the formation of atelectasis over time during HFJV in patients undergoing liver tumour ablation under general anaesthesia.
In this observational study twenty-five patients were studied. Repeated computed tomography (CT) scans were taken at the start of HFJV and every 15 minutes thereafter up until 45 minutes. From the CT images, four lung compartments were defined: hyperinflated, normoinflated, poorly inflated and atelectatic areas. The extension of each lung compartment was expressed as a percentage of the total lung area.
Atelectasis at 30 minutes, 7.9% (SD 3.5, p = 0.002) and at 45 minutes 8,1% (SD 5.2, p = 0.024), was significantly higher compared to baseline 5.6% (SD 2.5). The amount of normoinflated lung volumes were unchanged over the period studied. Only a few minor perioperative respiratory adverse events were noted.
Atelectasis during HFJV in stereotactic liver tumour ablation increased over the first 45 minutes but tended to stabilise with no impact on normoinflated lung volume. Using HFJV during stereotactic liver ablation is safe regarding formation of atelectasis.</description><subject>Ablation</subject><subject>Ablation (Surgery)</subject><subject>Anesthesia</subject><subject>Atelectasis</subject><subject>Atmospheric pressure</subject><subject>Biology and Life Sciences</subject><subject>Carbon dioxide</subject><subject>Care and treatment</subject><subject>Catheters</subject><subject>Clinical medicine</subject><subject>Complications and side effects</subject><subject>Computed tomography</subject><subject>General anesthesia</subject><subject>High frequencies</subject><subject>High-Frequency Jet Ventilation - adverse effects</subject><subject>High-Frequency Jet Ventilation - methods</subject><subject>Humans</subject><subject>Intubation</subject><subject>Liver</subject><subject>Liver cancer</subject><subject>Liver Neoplasms - diagnostic imaging</subject><subject>Liver Neoplasms - surgery</subject><subject>Lung cancer</subject><subject>Lungs</subject><subject>Mechanical ventilation</subject><subject>Medical instruments</subject><subject>Medicine and Health Sciences</subject><subject>Observational studies</subject><subject>Patient outcomes</subject><subject>Patients</subject><subject>Pulmonary Atelectasis - diagnostic imaging</subject><subject>Pulmonary Atelectasis - etiology</subject><subject>Radiation</subject><subject>Research and Analysis Methods</subject><subject>Respiration</subject><subject>Supine position</subject><subject>Surgery</subject><subject>Tomography</subject><subject>Tomography, X-Ray Computed</subject><subject>Tumors</subject><subject>Ventilation</subject><subject>Ventilators</subject><issn>1932-6203</issn><issn>1932-6203</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><sourceid>D8T</sourceid><sourceid>DOA</sourceid><recordid>eNp1kttu1DAQhiMEoqXwBggsIXFFik9x4iu0KqdKlRAScGs5jpN4SeLgw6J9CZ4Zb5NWuxe9suX55p-Z35NlLxG8RKRE77c2ukkOl7Od9CXEFS4xfZSdI05wzjAkj4_uZ9kz77cQFqRi7Gl2RkqIEKzIefbve5RTMEEGs9NAeq-9H_UUgG2BDHrQKkhvPGitGxNjJxCnRjvQm64HrdN_op7UHmx1ALuUZoYFaqIzUweGJOpAiGPqFch6CeYboOw4x3AI2dF2Ts79HvgQm_3z7EkrB69frOdF9vPzpx9XX_Obb1-urzY3uWK4CrksqGJF3UiuYEl1yWjLtNaKY4o5Q4QgCLFSrWKwZhWquCIEYt4mA1hTV5pcZK8X3XmwXqxWeoFLThlmVVEk4nohGiu3YnZmlG4vrDTi9sG6TkgXjBq04LiSNS8p5WVNa9lWRVlrinFBcKM05EkrX7T8Xz3H-kRtffqdblpQykrEEv_uQf6j-bW5rR6jKCDjmCT8wzpMrEedSk7ByeEk6zQymV50dieSS4wn85LCm1XB2fSjPjxgyUp1Mk1tptYmNTUar8QmTY8IRQVO1NsjqtdyCL23Qzx8vT8F6QIqZ713ur3vGEFxWPG7JsRhxcW64int1fG090l3O03-A0Et_Rg</recordid><startdate>20230403</startdate><enddate>20230403</enddate><creator>Galmén, Karolina</creator><creator>Jakobsson, Jan G</creator><creator>Perchiazzi, Gaetano</creator><creator>Freedman, Jacob</creator><creator>Harbut, Piotr</creator><general>Public Library of Science</general><general>Public Library of Science (PLoS)</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QG</scope><scope>7QL</scope><scope>7QO</scope><scope>7RV</scope><scope>7SN</scope><scope>7SS</scope><scope>7T5</scope><scope>7TG</scope><scope>7TM</scope><scope>7U9</scope><scope>7X2</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FD</scope><scope>8FE</scope><scope>8FG</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABJCF</scope><scope>ABUWG</scope><scope>AEUYN</scope><scope>AFKRA</scope><scope>ARAPS</scope><scope>ATCPS</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>D1I</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB.</scope><scope>KB0</scope><scope>KL.</scope><scope>L6V</scope><scope>LK8</scope><scope>M0K</scope><scope>M0S</scope><scope>M1P</scope><scope>M7N</scope><scope>M7P</scope><scope>M7S</scope><scope>NAPCQ</scope><scope>P5Z</scope><scope>P62</scope><scope>P64</scope><scope>PATMY</scope><scope>PDBOC</scope><scope>PHGZM</scope><scope>PHGZT</scope><scope>PIMPY</scope><scope>PJZUB</scope><scope>PKEHL</scope><scope>PPXIY</scope><scope>PQEST</scope><scope>PQGLB</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PTHSS</scope><scope>PYCSY</scope><scope>RC3</scope><scope>5PM</scope><scope>ACNBI</scope><scope>ADTPV</scope><scope>AOWAS</scope><scope>D8T</scope><scope>DF2</scope><scope>ZZAVC</scope><scope>DOA</scope><orcidid>https://orcid.org/0000-0002-4425-9044</orcidid></search><sort><creationdate>20230403</creationdate><title>Quantitative assessment of atelectasis formation under high frequency jet ventilation during liver tumour ablation-A computer tomography study</title><author>Galmén, Karolina ; Jakobsson, Jan G ; Perchiazzi, Gaetano ; Freedman, Jacob ; Harbut, Piotr</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c628t-a54c65bda9c074e764f6eeec9242961331002ccfc60b68189c33029f0536db8e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><topic>Ablation</topic><topic>Ablation (Surgery)</topic><topic>Anesthesia</topic><topic>Atelectasis</topic><topic>Atmospheric pressure</topic><topic>Biology and Life Sciences</topic><topic>Carbon dioxide</topic><topic>Care and treatment</topic><topic>Catheters</topic><topic>Clinical medicine</topic><topic>Complications and side effects</topic><topic>Computed tomography</topic><topic>General anesthesia</topic><topic>High frequencies</topic><topic>High-Frequency Jet Ventilation - 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Treated patients are in a supine position, under general anaesthesia and fully muscle relaxed. These are factors that are known to contribute to the formation of atelectasis. The HFJV-catheter is inserted freely inside the endotracheal tube and the system is therefore open to atmospheric pressure.
The aim of this study was to assess the formation of atelectasis over time during HFJV in patients undergoing liver tumour ablation under general anaesthesia.
In this observational study twenty-five patients were studied. Repeated computed tomography (CT) scans were taken at the start of HFJV and every 15 minutes thereafter up until 45 minutes. From the CT images, four lung compartments were defined: hyperinflated, normoinflated, poorly inflated and atelectatic areas. The extension of each lung compartment was expressed as a percentage of the total lung area.
Atelectasis at 30 minutes, 7.9% (SD 3.5, p = 0.002) and at 45 minutes 8,1% (SD 5.2, p = 0.024), was significantly higher compared to baseline 5.6% (SD 2.5). The amount of normoinflated lung volumes were unchanged over the period studied. Only a few minor perioperative respiratory adverse events were noted.
Atelectasis during HFJV in stereotactic liver tumour ablation increased over the first 45 minutes but tended to stabilise with no impact on normoinflated lung volume. Using HFJV during stereotactic liver ablation is safe regarding formation of atelectasis.</abstract><cop>United States</cop><pub>Public Library of Science</pub><pmid>37011083</pmid><doi>10.1371/journal.pone.0282724</doi><orcidid>https://orcid.org/0000-0002-4425-9044</orcidid><oa>free_for_read</oa></addata></record> |
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| identifier | ISSN: 1932-6203 |
| ispartof | PloS one, 2023-04, Vol.18 (4), p.e0282724 |
| issn | 1932-6203 1932-6203 |
| language | eng |
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| source | MEDLINE; DOAJ Directory of Open Access Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central; SWEPUB Freely available online; Free Full-Text Journals in Chemistry; Public Library of Science (PLoS) |
| subjects | Ablation Ablation (Surgery) Anesthesia Atelectasis Atmospheric pressure Biology and Life Sciences Carbon dioxide Care and treatment Catheters Clinical medicine Complications and side effects Computed tomography General anesthesia High frequencies High-Frequency Jet Ventilation - adverse effects High-Frequency Jet Ventilation - methods Humans Intubation Liver Liver cancer Liver Neoplasms - diagnostic imaging Liver Neoplasms - surgery Lung cancer Lungs Mechanical ventilation Medical instruments Medicine and Health Sciences Observational studies Patient outcomes Patients Pulmonary Atelectasis - diagnostic imaging Pulmonary Atelectasis - etiology Radiation Research and Analysis Methods Respiration Supine position Surgery Tomography Tomography, X-Ray Computed Tumors Ventilation Ventilators |
| title | Quantitative assessment of atelectasis formation under high frequency jet ventilation during liver tumour ablation-A computer tomography study |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-20T20%3A47%3A14IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_plos_&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Quantitative%20assessment%20of%20atelectasis%20formation%20under%20high%20frequency%20jet%20ventilation%20during%20liver%20tumour%20ablation-A%20computer%20tomography%20study&rft.jtitle=PloS%20one&rft.au=Galm%C3%A9n,%20Karolina&rft.date=2023-04-03&rft.volume=18&rft.issue=4&rft.spage=e0282724&rft.pages=e0282724-&rft.issn=1932-6203&rft.eissn=1932-6203&rft_id=info:doi/10.1371/journal.pone.0282724&rft_dat=%3Cgale_plos_%3EA744134152%3C/gale_plos_%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2794626855&rft_id=info:pmid/37011083&rft_galeid=A744134152&rft_doaj_id=oai_doaj_org_article_928ab974497b4baf857be422532dce09&rfr_iscdi=true |