Identification of molecularly unique tumor-associated mesenchymal stromal cells in breast cancer patients

The tumor microenvironment is a complex mixture of cell types that bi-directionally interact and influence tumor initiation, progression, recurrence, and patient survival. Mesenchymal stromal cells (MSCs) of the tumor microenvironment engage in crosstalk with cancer cells to mediate epigenetic contr...

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Veröffentlicht in:	PloS one 2023-03, Vol.18 (3), p.e0282473-e0282473
Hauptverfasser:	Gordon, Jonathan A R, Evans, Mark F, Ghule, Prachi N, Lee, Kyra, Vacek, Pamela, Sprague, Brian L, Weaver, Donald L, Stein, Gary S, Stein, Janet L
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Biology and Life Sciences Bone marrow Breast cancer Breast Neoplasms - diagnosis Breast Neoplasms - genetics Cell interactions Cell Line, Tumor Cell Proliferation Cell survival Colorectal cancer Crosstalk Cytokines Diagnosis Epigenetic inheritance Epigenetics Epithelial-Mesenchymal Transition - genetics Extracellular matrix Gastric cancer Gene expression Genetic aspects Growth factors Health aspects Humans Medicine and Health Sciences Mesenchymal stem cells Mesenchymal Stem Cells - metabolism Microscopy Morphology Patients Phenotypes Prostate cancer Signal Transduction Stem cells Stromal cells Stromal Cells - metabolism Transcriptome Tumor microenvironment Tumor Microenvironment - genetics Tumors
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