Polygenic risk scores for asthma and allergic disease associate with COVID-19 severity in 9/11 responders

Genetic factors contribute to individual differences in the severity of coronavirus disease 2019 (COVID-19). A portion of genetic predisposition can be captured using polygenic risk scores (PRS). Relatively little is known about the associations between PRS and COVID-19 severity or post-acute COVID-...

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Veröffentlicht in:	PloS one 2023-03, Vol.18 (3), p.e0282271-e0282271
Hauptverfasser:	Waszczuk, Monika A, Morozova, Olga, Lhuillier, Elizabeth, Docherty, Anna R, Shabalin, Andrey A, Yang, Xiaohua, Carr, Melissa A, Clouston, Sean A P, Kotov, Roman, Luft, Benjamin J
Format:	Artikel
Sprache:	eng
Schlagworte:	Allergic diseases Allergic reaction Allergy Asthma Asthma - diagnosis Asthma - genetics Asymptomatic Biology and Life Sciences Biomarkers Cardiovascular disease Coronary artery disease Coronary vessels Coronaviruses COVID-19 COVID-19 - genetics Diabetes Diabetes mellitus Diabetes Mellitus, Type 2 Diagnosis Electronic health records Female Genetic factors Health risk assessment Heart diseases Hospitalization Humans Infections Laboratories Male Medical records Medicine and Health Sciences Nervous system Post traumatic stress disorder Respiratory diseases Risk Factors SARS-CoV-2 - genetics September 11 terrorist attacks-2001 Severe acute respiratory syndrome coronavirus 2 Variables Vein & artery diseases Viral diseases
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