Clinic-based SAMBA-II vs centralized laboratory viral load assays among HIV-1 infected children, adolescents and young adults in rural Zimbabwe: A randomized controlled trial

In Zimbabwe, children, adolescents and young adults living with HIV (CALWH) who are on public health antiretroviral therapy (ART) have inadequate viral load (VL) suppression. We assessed whether a clinic-based VL monitoring could decrease 12-month virologic failure rates among these CALWH. The study...

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Veröffentlicht in:	PloS one 2023-02, Vol.18 (2), p.e0281279-e0281279
Hauptverfasser:	Kouamou, Vinie, Machekano, Rhoderick, Mapangisana, Tichaona, Maposhere, Caroline, Mutetwa, Reggie, Manasa, Justen, Shamu, Tinei, McCarty, Kathy, Munyati, Shungu, Mutsvangwa, Junior, Bogoshi, Mampedi, Israelski, Dennis, Katzenstein, David
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adolescents Adults Anti-HIV Agents - therapeutic use Antiretroviral agents Antiretroviral drugs Antiretroviral therapy Assaying Biological products industry Biology and Life Sciences Child Children Clinics Complications and side effects Consent Counseling Diagnosis Drug resistance Ethylenediaminetetraacetic acid Failure rates Female Highly active antiretroviral therapy HIV HIV (Viruses) HIV Infections - drug therapy HIV Seropositivity - drug therapy HIV-1 Human immunodeficiency virus Humans Laboratories Male Medicine and Health Sciences Monitoring Patient outcomes People and Places Pharmacy Plasma Protease inhibitors Proteases Proteinase inhibitors Public health Rural areas Switching Tat protein Teenagers Viral Load - methods Vital signs Young Adult Young adults Zimbabwe - epidemiology
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