High glucose promotes regulatory T cell differentiation

The consumption of processed foods and sugary sodas in Western diets correlates with an increased incidence of obesity, metabolic syndromes such as type 2 diabetes, cardiovascular diseases, and autoimmune diseases including inflammatory bowel disease and rheumatoid arthritis. All these diseases have...

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Veröffentlicht in:	PloS one 2023-02, Vol.18 (2), p.e0280916-e0280916
Hauptverfasser:	Pitmon, Elise, Meehan, Eileen Victoria, Ahmadi, Elham, Adler, Adam J, Wang, Kepeng
Format:	Artikel
Sprache:	eng
Schlagworte:	AKT protein Arthritis Autoimmune diseases Biology and life sciences Cardiovascular diseases CD4 antigen Cell Differentiation Cells Cytokines Diabetes mellitus Diabetes mellitus (non-insulin dependent) Diabetes Mellitus, Type 2 - metabolism Differentiation (biology) Effector cells Fatty acids Flow cytometry Food consumption Food processing Glucose Glucose - metabolism Glycolysis Health aspects Homeostasis Humans Immunoregulation Inflammation Inflammatory bowel diseases Lactates - metabolism Lactic acid Lymphocytes Lymphocytes T Medicine and health sciences Metabolic disorders Metabolic syndrome Metabolism Metabolites Oxidative phosphorylation Phosphorylation Physical Sciences Processed foods Research and Analysis Methods Rheumatoid arthritis T cells T-Lymphocytes, Regulatory TOR protein Transcription factors Tumors
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