Effect of matrine in MAC-T cells and their transcriptome analysis: A basic study

Matrine, an alkaloid derived from herbal medicine, has a wide range of biological activities, including antibacterial. Matrine was toxic to multiple cells at high concentrations. Bovine mammary epithelial cells (MAC-T) could be used as model cells for cow breast. Matrine was a feasible option to rep...

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Veröffentlicht in:	PloS one 2023-01, Vol.18 (1), p.e0280905
Hauptverfasser:	Zhang, Zhao, Yang, Yuze, Yan, Lijiao, Wan, Xuerui, Sun, Kangyongjie, Gou, Huitian, Ding, Jucai, Peng, Jie, Liu, Guo, Wang, Chuan
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Animals Antibiotics Antineoplastic Agents - pharmacology Apoptosis Biology and Life Sciences Cancer Care and treatment Cattle Cells Computer and Information Sciences Cytokines Cytokines - pharmacology Cytotoxicity Diagnosis E coli Encyclopedias Epithelial cells Epithelium Female Flow cytometry Genes Genomes Health aspects Herbal medicine Lymphocytes Lymphocytes T Mammary gland Mastitis Matrines Medicine and Health Sciences Medicine, Botanic Medicine, Herbal p53 Protein Penicillin Prevention Proteins Quinolizines - pharmacology Quinolizines - therapeutic use Receptors RNA T cells T-Lymphocytes Toxicity Transcriptome Transcriptomes Tumor proteins Viral proteins
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