High-throughput screen in vitro identifies dasatinib as a candidate for combinatorial treatment with HER2-targeting drugs in breast cancer

Human epidermal growth factor receptor 2-positive (HER2+) breast cancer is an aggressive subtype of this disease. Targeted treatment has improved outcome, but there is still a need for new therapeutic strategies as some patients respond poorly to treatment. Our aim was to identify compounds that sub...

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Veröffentlicht in:PloS one 2023-01, Vol.18 (1), p.e0280507
Hauptverfasser: Normann, Lisa Svartdal, Haugen, Mads Haugland, Hongisto, Vesa, Aure, Miriam Ragle, Leivonen, Suvi-Katri, Kristensen, Vessela N, Tahiri, Andliena, Engebraaten, Olav, Sahlberg, Kristine Kleivi, Mælandsmo, Gunhild Mari
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Sprache:eng
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