Association of RNA-modification "writer" genes with prognosis and response to immunotherapy in patients with low-grade glioma

RNA modification is a key regulatory mechanism involved in tumorigenesis, tumor progression, and the immune response. However, the potential role of RNA modification "writer" genes in the immune microenvironment of gliomas and their effect on the response to immunotherapy remains unclear....

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Veröffentlicht in:	PloS one 2023-01, Vol.18 (1), p.e0279119-e0279119
Hauptverfasser:	Zhang, Lupeng, Qu, Chiwen, Shi, Chen, Wu, Fan, Tang, Yifan, Li, Yue, Li, Jinlong, Feng, Huicong, Zhong, Suye, Yang, Jun, Zeng, Xiaomin, Peng, Xiaoning
Format:	Artikel
Sprache:	eng
Schlagworte:	Algorithms Biology and Life Sciences Brain tumors Care and treatment CD4 antigen Chemotherapy Datasets Drug resistance Enzymes Epigenetics Evaluation Gene expression Genes Genetic aspects Genomes Genomics Glioma Glioma - diagnosis Glioma - genetics Glioma - therapy Gliomas Health aspects Humans Immune response Immune system Immunotherapy Lymphocytes Lymphocytes T Medical prognosis Medicine and Health Sciences Microenvironments Mutation Nervous system Nomograms Nomographs Patient outcomes Prediction models Principal components analysis Prognosis Radiation therapy Regulatory mechanisms (biology) Research and analysis methods Ribonucleic acid RNA RNA modification RNA processing Software packages Survival analysis Tumor Microenvironment - genetics Tumorigenesis Tumors
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