Physiological adaptations and myocellular stress in short-term, high-frequency blood flow restriction training: A scoping review
High frequency (1-2 times per day) low-intensity blood flow restriction (BFR) training has been recommended as a prescription approach for short durations of time to maximize relevant physiological adaptations. However, some studies demonstrate negative physiological changes after short periods of h...
Gespeichert in:
| Veröffentlicht in: | PloS one 2022-12, Vol.17 (12), p.e0279811-e0279811 |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | e0279811 |
|---|---|
| container_issue | 12 |
| container_start_page | e0279811 |
| container_title | PloS one |
| container_volume | 17 |
| creator | de Queiros, Victor Sabino Rolnick, Nicholas de Alcântara Varela, Phelipe Wilde Cabral, Breno Guilherme de Araújo Tinôco Silva Dantas, Paulo Moreira |
| description | High frequency (1-2 times per day) low-intensity blood flow restriction (BFR) training has been recommended as a prescription approach for short durations of time to maximize relevant physiological adaptations. However, some studies demonstrate negative physiological changes after short periods of high-frequency BFR training, including prolonged strength decline and muscle fiber atrophy.
To provide a comprehensive overview of short-term, high-frequency blood flow restriction training, including main adaptations, myocellular stress, limitations in the literature, and future perspectives.
A systematic search of electronic databases (Scopus, PubMed®, and Web of Science) was performed from the earliest record to April 23, 2022. Two independent reviewers selected experimental studies that analyzed physical training protocols (aerobic or resistance) of high weekly frequency (>4 days/week) and short durations (≤3 weeks).
In total, 22 studies were included in this review. The samples were composed exclusively of young predominantly male individuals. Muscle strength and hypertrophy were the main outcomes analyzed in the studies. In general, studies have demonstrated increases in strength and muscle size after short term (1-3 weeks), high-frequency low-intensity BFR training, non-failure, but not after control conditions (non-BFR; equalized training volume). Under failure conditions, some studies have demonstrated strength decline and muscle fiber atrophy after BFR conditions, accompanying increases in muscle damage markers. Significant limitations exist in the current HF-BFR literature due to large heterogeneities in methodologies.
The synthesis presented indicates that short-term, high-frequency BFR training programs can generate significant neuromuscular adaptations. However, in resistance training to failure, strength declines and muscle fiber atrophy were reported. Currently, there are no studies analyzing low-frequency vs. high-frequency in short-term BFR training. Comparisons between resistance exercises of similar intensities (e.g., combined effort) are lacking, limiting conclusions on whether the effect is a product of proximity to failure or a specific effect of BFR. |
| doi_str_mv | 10.1371/journal.pone.0279811 |
| format | Article |
| fullrecord | <record><control><sourceid>gale_plos_</sourceid><recordid>TN_cdi_plos_journals_2759699346</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A731743544</galeid><doaj_id>oai_doaj_org_article_b7fa9a49eca44362a181c7434dbb8ea4</doaj_id><sourcerecordid>A731743544</sourcerecordid><originalsourceid>FETCH-LOGICAL-c692t-23db3df1dfb2add37629be5a5cc8bd7388e3e67dab880ac541a36537f91c21d93</originalsourceid><addsrcrecordid>eNqNk11rFDEUhgdRbK3-A9GAIArOOpnMR-KFsBQ_FgoVv27DmSQzk5KZrEmmde_86Wa627IrvZBcJCTPeXPOm5wkeYqzBSY1fnthJzeCWaztqBZZXjOK8b3kGDOSp1Wekft766PkkfcXWVYSWlUPkyNSlbTAZX2c_PnSb7y2xnZagEEgYR0gaDt6BKNEw8YKZcxkwCEfnPIe6RH53rqQBuWGN6jXXZ-2Tv2a1Cg2qDHWStQae4UiHZwWsxgKDvSox-4dWiIv7Dou4_mlVlePkwctGK-e7OaT5MfHD99PP6dn559Wp8uzVFQsD2lOZENki2Xb5CAlqaucNaqEUgjayJpQqoiqagkNpRmIssAQiyR1y7DIsWTkJHm-1V0b6_nOPM_zumQVY6SoIrHaEtLCBV87PYDbcAuaX29Y13FwQQujeFO3wKBgSkBRkCoHTLGoC1LIpqEKiqj1fnfb1AxKCjVGB8yB6OHJqHve2UvOaEYwndN9tRNwNlrrAx-0n58CRmWnbd6spITN6It_0Lur21EdxAL02Np4r5hF-bImOCZfFnPeizuoOKQatIg_rdVx_yDg9UFAZIL6HTqYvOerb1__nz3_eci-3GN7BSb03prp-msegsUWFM5671R7azLO-NwoN27wuVH4rlFi2LP9B7oNuukM8hdiZxFa</addsrcrecordid><sourcetype>Open Website</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2759699346</pqid></control><display><type>article</type><title>Physiological adaptations and myocellular stress in short-term, high-frequency blood flow restriction training: A scoping review</title><source>MEDLINE</source><source>DOAJ Directory of Open Access Journals</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>PubMed Central</source><source>Free Full-Text Journals in Chemistry</source><source>Public Library of Science (PLoS)</source><creator>de Queiros, Victor Sabino ; Rolnick, Nicholas ; de Alcântara Varela, Phelipe Wilde ; Cabral, Breno Guilherme de Araújo Tinôco ; Silva Dantas, Paulo Moreira</creator><creatorcontrib>de Queiros, Victor Sabino ; Rolnick, Nicholas ; de Alcântara Varela, Phelipe Wilde ; Cabral, Breno Guilherme de Araújo Tinôco ; Silva Dantas, Paulo Moreira</creatorcontrib><description>High frequency (1-2 times per day) low-intensity blood flow restriction (BFR) training has been recommended as a prescription approach for short durations of time to maximize relevant physiological adaptations. However, some studies demonstrate negative physiological changes after short periods of high-frequency BFR training, including prolonged strength decline and muscle fiber atrophy.
To provide a comprehensive overview of short-term, high-frequency blood flow restriction training, including main adaptations, myocellular stress, limitations in the literature, and future perspectives.
A systematic search of electronic databases (Scopus, PubMed®, and Web of Science) was performed from the earliest record to April 23, 2022. Two independent reviewers selected experimental studies that analyzed physical training protocols (aerobic or resistance) of high weekly frequency (>4 days/week) and short durations (≤3 weeks).
In total, 22 studies were included in this review. The samples were composed exclusively of young predominantly male individuals. Muscle strength and hypertrophy were the main outcomes analyzed in the studies. In general, studies have demonstrated increases in strength and muscle size after short term (1-3 weeks), high-frequency low-intensity BFR training, non-failure, but not after control conditions (non-BFR; equalized training volume). Under failure conditions, some studies have demonstrated strength decline and muscle fiber atrophy after BFR conditions, accompanying increases in muscle damage markers. Significant limitations exist in the current HF-BFR literature due to large heterogeneities in methodologies.
The synthesis presented indicates that short-term, high-frequency BFR training programs can generate significant neuromuscular adaptations. However, in resistance training to failure, strength declines and muscle fiber atrophy were reported. Currently, there are no studies analyzing low-frequency vs. high-frequency in short-term BFR training. Comparisons between resistance exercises of similar intensities (e.g., combined effort) are lacking, limiting conclusions on whether the effect is a product of proximity to failure or a specific effect of BFR.</description><identifier>ISSN: 1932-6203</identifier><identifier>EISSN: 1932-6203</identifier><identifier>DOI: 10.1371/journal.pone.0279811</identifier><identifier>PMID: 36584157</identifier><language>eng</language><publisher>United States: Public Library of Science</publisher><subject>Adaptation ; Adaptation, Physiological ; Adaptations ; Aerobics ; Analysis ; Atrophy ; Biology and Life Sciences ; Blood ; Blood flow ; Blood Flow Restriction Therapy ; Engineering and Technology ; Exercise ; Failure ; Female ; Frequency analysis ; Humans ; Hypertrophy ; Influence ; Intervention ; Male ; Medicine and Health Sciences ; Muscle strength ; Muscle Strength - physiology ; Muscle, Skeletal - physiology ; Physical fitness ; Physical training ; Physiological aspects ; Physiology ; Reading ; Regional Blood Flow - physiology ; Research and Analysis Methods ; Resistance training ; Resistance Training - methods ; Strength training ; Stress (Physiology) ; Weight training</subject><ispartof>PloS one, 2022-12, Vol.17 (12), p.e0279811-e0279811</ispartof><rights>Copyright: © 2022 de Queiros et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.</rights><rights>COPYRIGHT 2022 Public Library of Science</rights><rights>2022 de Queiros et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>2022 de Queiros et al 2022 de Queiros et al</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c692t-23db3df1dfb2add37629be5a5cc8bd7388e3e67dab880ac541a36537f91c21d93</citedby><cites>FETCH-LOGICAL-c692t-23db3df1dfb2add37629be5a5cc8bd7388e3e67dab880ac541a36537f91c21d93</cites><orcidid>0000-0003-4117-0295</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC9803189/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC9803189/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,860,881,2096,2915,23845,27901,27902,53766,53768,79342,79343</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/36584157$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>de Queiros, Victor Sabino</creatorcontrib><creatorcontrib>Rolnick, Nicholas</creatorcontrib><creatorcontrib>de Alcântara Varela, Phelipe Wilde</creatorcontrib><creatorcontrib>Cabral, Breno Guilherme de Araújo Tinôco</creatorcontrib><creatorcontrib>Silva Dantas, Paulo Moreira</creatorcontrib><title>Physiological adaptations and myocellular stress in short-term, high-frequency blood flow restriction training: A scoping review</title><title>PloS one</title><addtitle>PLoS One</addtitle><description>High frequency (1-2 times per day) low-intensity blood flow restriction (BFR) training has been recommended as a prescription approach for short durations of time to maximize relevant physiological adaptations. However, some studies demonstrate negative physiological changes after short periods of high-frequency BFR training, including prolonged strength decline and muscle fiber atrophy.
To provide a comprehensive overview of short-term, high-frequency blood flow restriction training, including main adaptations, myocellular stress, limitations in the literature, and future perspectives.
A systematic search of electronic databases (Scopus, PubMed®, and Web of Science) was performed from the earliest record to April 23, 2022. Two independent reviewers selected experimental studies that analyzed physical training protocols (aerobic or resistance) of high weekly frequency (>4 days/week) and short durations (≤3 weeks).
In total, 22 studies were included in this review. The samples were composed exclusively of young predominantly male individuals. Muscle strength and hypertrophy were the main outcomes analyzed in the studies. In general, studies have demonstrated increases in strength and muscle size after short term (1-3 weeks), high-frequency low-intensity BFR training, non-failure, but not after control conditions (non-BFR; equalized training volume). Under failure conditions, some studies have demonstrated strength decline and muscle fiber atrophy after BFR conditions, accompanying increases in muscle damage markers. Significant limitations exist in the current HF-BFR literature due to large heterogeneities in methodologies.
The synthesis presented indicates that short-term, high-frequency BFR training programs can generate significant neuromuscular adaptations. However, in resistance training to failure, strength declines and muscle fiber atrophy were reported. Currently, there are no studies analyzing low-frequency vs. high-frequency in short-term BFR training. Comparisons between resistance exercises of similar intensities (e.g., combined effort) are lacking, limiting conclusions on whether the effect is a product of proximity to failure or a specific effect of BFR.</description><subject>Adaptation</subject><subject>Adaptation, Physiological</subject><subject>Adaptations</subject><subject>Aerobics</subject><subject>Analysis</subject><subject>Atrophy</subject><subject>Biology and Life Sciences</subject><subject>Blood</subject><subject>Blood flow</subject><subject>Blood Flow Restriction Therapy</subject><subject>Engineering and Technology</subject><subject>Exercise</subject><subject>Failure</subject><subject>Female</subject><subject>Frequency analysis</subject><subject>Humans</subject><subject>Hypertrophy</subject><subject>Influence</subject><subject>Intervention</subject><subject>Male</subject><subject>Medicine and Health Sciences</subject><subject>Muscle strength</subject><subject>Muscle Strength - physiology</subject><subject>Muscle, Skeletal - physiology</subject><subject>Physical fitness</subject><subject>Physical training</subject><subject>Physiological aspects</subject><subject>Physiology</subject><subject>Reading</subject><subject>Regional Blood Flow - physiology</subject><subject>Research and Analysis Methods</subject><subject>Resistance training</subject><subject>Resistance Training - methods</subject><subject>Strength training</subject><subject>Stress (Physiology)</subject><subject>Weight training</subject><issn>1932-6203</issn><issn>1932-6203</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><sourceid>DOA</sourceid><recordid>eNqNk11rFDEUhgdRbK3-A9GAIArOOpnMR-KFsBQ_FgoVv27DmSQzk5KZrEmmde_86Wa627IrvZBcJCTPeXPOm5wkeYqzBSY1fnthJzeCWaztqBZZXjOK8b3kGDOSp1Wekft766PkkfcXWVYSWlUPkyNSlbTAZX2c_PnSb7y2xnZagEEgYR0gaDt6BKNEw8YKZcxkwCEfnPIe6RH53rqQBuWGN6jXXZ-2Tv2a1Cg2qDHWStQae4UiHZwWsxgKDvSox-4dWiIv7Dou4_mlVlePkwctGK-e7OaT5MfHD99PP6dn559Wp8uzVFQsD2lOZENki2Xb5CAlqaucNaqEUgjayJpQqoiqagkNpRmIssAQiyR1y7DIsWTkJHm-1V0b6_nOPM_zumQVY6SoIrHaEtLCBV87PYDbcAuaX29Y13FwQQujeFO3wKBgSkBRkCoHTLGoC1LIpqEKiqj1fnfb1AxKCjVGB8yB6OHJqHve2UvOaEYwndN9tRNwNlrrAx-0n58CRmWnbd6spITN6It_0Lur21EdxAL02Np4r5hF-bImOCZfFnPeizuoOKQatIg_rdVx_yDg9UFAZIL6HTqYvOerb1__nz3_eci-3GN7BSb03prp-msegsUWFM5671R7azLO-NwoN27wuVH4rlFi2LP9B7oNuukM8hdiZxFa</recordid><startdate>20221230</startdate><enddate>20221230</enddate><creator>de Queiros, Victor Sabino</creator><creator>Rolnick, Nicholas</creator><creator>de Alcântara Varela, Phelipe Wilde</creator><creator>Cabral, Breno Guilherme de Araújo Tinôco</creator><creator>Silva Dantas, Paulo Moreira</creator><general>Public Library of Science</general><general>Public Library of Science (PLoS)</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>IOV</scope><scope>ISR</scope><scope>3V.</scope><scope>7QG</scope><scope>7QL</scope><scope>7QO</scope><scope>7RV</scope><scope>7SN</scope><scope>7SS</scope><scope>7T5</scope><scope>7TG</scope><scope>7TM</scope><scope>7U9</scope><scope>7X2</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FD</scope><scope>8FE</scope><scope>8FG</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABJCF</scope><scope>ABUWG</scope><scope>AEUYN</scope><scope>AFKRA</scope><scope>ARAPS</scope><scope>ATCPS</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>D1I</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB.</scope><scope>KB0</scope><scope>KL.</scope><scope>L6V</scope><scope>LK8</scope><scope>M0K</scope><scope>M0S</scope><scope>M1P</scope><scope>M7N</scope><scope>M7P</scope><scope>M7S</scope><scope>NAPCQ</scope><scope>P5Z</scope><scope>P62</scope><scope>P64</scope><scope>PATMY</scope><scope>PDBOC</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PTHSS</scope><scope>PYCSY</scope><scope>RC3</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope><orcidid>https://orcid.org/0000-0003-4117-0295</orcidid></search><sort><creationdate>20221230</creationdate><title>Physiological adaptations and myocellular stress in short-term, high-frequency blood flow restriction training: A scoping review</title><author>de Queiros, Victor Sabino ; Rolnick, Nicholas ; de Alcântara Varela, Phelipe Wilde ; Cabral, Breno Guilherme de Araújo Tinôco ; Silva Dantas, Paulo Moreira</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c692t-23db3df1dfb2add37629be5a5cc8bd7388e3e67dab880ac541a36537f91c21d93</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Adaptation</topic><topic>Adaptation, Physiological</topic><topic>Adaptations</topic><topic>Aerobics</topic><topic>Analysis</topic><topic>Atrophy</topic><topic>Biology and Life Sciences</topic><topic>Blood</topic><topic>Blood flow</topic><topic>Blood Flow Restriction Therapy</topic><topic>Engineering and Technology</topic><topic>Exercise</topic><topic>Failure</topic><topic>Female</topic><topic>Frequency analysis</topic><topic>Humans</topic><topic>Hypertrophy</topic><topic>Influence</topic><topic>Intervention</topic><topic>Male</topic><topic>Medicine and Health Sciences</topic><topic>Muscle strength</topic><topic>Muscle Strength - physiology</topic><topic>Muscle, Skeletal - physiology</topic><topic>Physical fitness</topic><topic>Physical training</topic><topic>Physiological aspects</topic><topic>Physiology</topic><topic>Reading</topic><topic>Regional Blood Flow - physiology</topic><topic>Research and Analysis Methods</topic><topic>Resistance training</topic><topic>Resistance Training - methods</topic><topic>Strength training</topic><topic>Stress (Physiology)</topic><topic>Weight training</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>de Queiros, Victor Sabino</creatorcontrib><creatorcontrib>Rolnick, Nicholas</creatorcontrib><creatorcontrib>de Alcântara Varela, Phelipe Wilde</creatorcontrib><creatorcontrib>Cabral, Breno Guilherme de Araújo Tinôco</creatorcontrib><creatorcontrib>Silva Dantas, Paulo Moreira</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Gale In Context: Opposing Viewpoints</collection><collection>Gale In Context: Science</collection><collection>ProQuest Central (Corporate)</collection><collection>Animal Behavior Abstracts</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Biotechnology Research Abstracts</collection><collection>Nursing & Allied Health Database</collection><collection>Ecology Abstracts</collection><collection>Entomology Abstracts (Full archive)</collection><collection>Immunology Abstracts</collection><collection>Meteorological & Geoastrophysical Abstracts</collection><collection>Nucleic Acids Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Agricultural Science Collection</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Technology Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Materials Science & Engineering Collection</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest One Sustainability</collection><collection>ProQuest Central UK/Ireland</collection><collection>Advanced Technologies & Aerospace Collection</collection><collection>Agricultural & Environmental Science Collection</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Technology Collection (ProQuest)</collection><collection>Natural Science Collection</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Materials Science Collection</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Materials Science Database</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Meteorological & Geoastrophysical Abstracts - Academic</collection><collection>ProQuest Engineering Collection</collection><collection>ProQuest Biological Science Collection</collection><collection>Agricultural Science Database</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biological Science Database</collection><collection>Engineering Database</collection><collection>Nursing & Allied Health Premium</collection><collection>Advanced Technologies & Aerospace Database</collection><collection>ProQuest Advanced Technologies & Aerospace Collection</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Environmental Science Database</collection><collection>Materials Science Collection</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>Engineering Collection</collection><collection>Environmental Science Collection</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>DOAJ Directory of Open Access Journals</collection><jtitle>PloS one</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>de Queiros, Victor Sabino</au><au>Rolnick, Nicholas</au><au>de Alcântara Varela, Phelipe Wilde</au><au>Cabral, Breno Guilherme de Araújo Tinôco</au><au>Silva Dantas, Paulo Moreira</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Physiological adaptations and myocellular stress in short-term, high-frequency blood flow restriction training: A scoping review</atitle><jtitle>PloS one</jtitle><addtitle>PLoS One</addtitle><date>2022-12-30</date><risdate>2022</risdate><volume>17</volume><issue>12</issue><spage>e0279811</spage><epage>e0279811</epage><pages>e0279811-e0279811</pages><issn>1932-6203</issn><eissn>1932-6203</eissn><abstract>High frequency (1-2 times per day) low-intensity blood flow restriction (BFR) training has been recommended as a prescription approach for short durations of time to maximize relevant physiological adaptations. However, some studies demonstrate negative physiological changes after short periods of high-frequency BFR training, including prolonged strength decline and muscle fiber atrophy.
To provide a comprehensive overview of short-term, high-frequency blood flow restriction training, including main adaptations, myocellular stress, limitations in the literature, and future perspectives.
A systematic search of electronic databases (Scopus, PubMed®, and Web of Science) was performed from the earliest record to April 23, 2022. Two independent reviewers selected experimental studies that analyzed physical training protocols (aerobic or resistance) of high weekly frequency (>4 days/week) and short durations (≤3 weeks).
In total, 22 studies were included in this review. The samples were composed exclusively of young predominantly male individuals. Muscle strength and hypertrophy were the main outcomes analyzed in the studies. In general, studies have demonstrated increases in strength and muscle size after short term (1-3 weeks), high-frequency low-intensity BFR training, non-failure, but not after control conditions (non-BFR; equalized training volume). Under failure conditions, some studies have demonstrated strength decline and muscle fiber atrophy after BFR conditions, accompanying increases in muscle damage markers. Significant limitations exist in the current HF-BFR literature due to large heterogeneities in methodologies.
The synthesis presented indicates that short-term, high-frequency BFR training programs can generate significant neuromuscular adaptations. However, in resistance training to failure, strength declines and muscle fiber atrophy were reported. Currently, there are no studies analyzing low-frequency vs. high-frequency in short-term BFR training. Comparisons between resistance exercises of similar intensities (e.g., combined effort) are lacking, limiting conclusions on whether the effect is a product of proximity to failure or a specific effect of BFR.</abstract><cop>United States</cop><pub>Public Library of Science</pub><pmid>36584157</pmid><doi>10.1371/journal.pone.0279811</doi><tpages>e0279811</tpages><orcidid>https://orcid.org/0000-0003-4117-0295</orcidid><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1932-6203 |
| ispartof | PloS one, 2022-12, Vol.17 (12), p.e0279811-e0279811 |
| issn | 1932-6203 1932-6203 |
| language | eng |
| recordid | cdi_plos_journals_2759699346 |
| source | MEDLINE; DOAJ Directory of Open Access Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central; Free Full-Text Journals in Chemistry; Public Library of Science (PLoS) |
| subjects | Adaptation Adaptation, Physiological Adaptations Aerobics Analysis Atrophy Biology and Life Sciences Blood Blood flow Blood Flow Restriction Therapy Engineering and Technology Exercise Failure Female Frequency analysis Humans Hypertrophy Influence Intervention Male Medicine and Health Sciences Muscle strength Muscle Strength - physiology Muscle, Skeletal - physiology Physical fitness Physical training Physiological aspects Physiology Reading Regional Blood Flow - physiology Research and Analysis Methods Resistance training Resistance Training - methods Strength training Stress (Physiology) Weight training |
| title | Physiological adaptations and myocellular stress in short-term, high-frequency blood flow restriction training: A scoping review |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-06T16%3A14%3A05IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_plos_&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Physiological%20adaptations%20and%20myocellular%20stress%20in%20short-term,%20high-frequency%20blood%20flow%20restriction%20training:%20A%20scoping%20review&rft.jtitle=PloS%20one&rft.au=de%20Queiros,%20Victor%20Sabino&rft.date=2022-12-30&rft.volume=17&rft.issue=12&rft.spage=e0279811&rft.epage=e0279811&rft.pages=e0279811-e0279811&rft.issn=1932-6203&rft.eissn=1932-6203&rft_id=info:doi/10.1371/journal.pone.0279811&rft_dat=%3Cgale_plos_%3EA731743544%3C/gale_plos_%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2759699346&rft_id=info:pmid/36584157&rft_galeid=A731743544&rft_doaj_id=oai_doaj_org_article_b7fa9a49eca44362a181c7434dbb8ea4&rfr_iscdi=true |