Rebamipide treatment ameliorates obesity phenotype by regulation of immune cells and adipocytes

Obesity is a medical term used to describe an over-accumulation of adipose tissue. It causes abnormal physiological and pathological processes in the body. Obesity is associated with systemic inflammation and abnormalities in immune cell function. Rebamipide, an amino acid derivative of 2-(1H)-quino...

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Veröffentlicht in:	PloS one 2022-12, Vol.17 (12), p.e0277692-e0277692
Hauptverfasser:	Jhun, JooYeon, Moon, Jeonghyeon, Kim, Se-Young, Cho, Keun-Hyung, Na, Hyun Sik, Choi, JeongWon, Jung, Yoon Ju, Song, Kyo Young, Min, Jun-Ki, Cho, Mi-La
Format:	Artikel
Sprache:	eng
Schlagworte:	3T3-L1 Cells Abnormalities Adipocytes Adipocytes - metabolism Adipose tissue Adipose Tissue - metabolism Amino acids Analysis Animals Antibodies Arthritis Bioaccumulation Biology and Life Sciences Blood glucose Body fat Body weight Body weight gain Care and treatment Cell differentiation Cell lines Cholesterol Cytokines Diabetes Diet Diet, High-Fat - adverse effects Glucose Helper cells High fat diet Immune system Inflammation Inflammation - metabolism Insulin Insulin Resistance Lipid metabolism Lipids Lipoproteins Lymphocytes T Macrophages Medicine and Health Sciences Metabolism Mice Mice, Inbred C57BL Obesity Obesity - complications Osteoarthritis Oxidative stress Patient outcomes Phenotype Phenotypes Quinolones - metabolism Quinolones - pharmacology Quinolones - therapeutic use Regulation Research and Analysis Methods Research ethics Statistical analysis Tumor necrosis factor-TNF
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