Quality of life among patients with the common chronic disease during COVID-19 pandemic in Northwest Ethiopia: A structural equation modelling

Improving Quality of Life (QoL) for patients with chronic diseases is a critical step in controlling disease progression and preventing complications. The COVID-19 pandemic has hampered chronic disease management, lowering patients' quality of life. Thus, we aimed to assess the quality of life...

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Veröffentlicht in:PloS one 2022-12, Vol.17 (12), p.e0278557
Hauptverfasser: Ayele, Tadesse Awoke, Shibru Fanta, Habtewold, Mequanent Sisay, Malede, Melese Yilma, Tesfahun, Fentie, Melkitu, Azale, Telake, Belachew, Tariku, Shitu, Kegnie, Alamneh, Tesfa Sewunet
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container_issue 12
container_start_page e0278557
container_title PloS one
container_volume 17
creator Ayele, Tadesse Awoke
Shibru Fanta, Habtewold
Mequanent Sisay, Malede
Melese Yilma, Tesfahun
Fentie, Melkitu
Azale, Telake
Belachew, Tariku
Shitu, Kegnie
Alamneh, Tesfa Sewunet
description Improving Quality of Life (QoL) for patients with chronic diseases is a critical step in controlling disease progression and preventing complications. The COVID-19 pandemic has hampered chronic disease management, lowering patients' quality of life. Thus, we aimed to assess the quality of life and its determinants in patients with common chronic diseases, in Northwest Ethiopia during the COVID-19 pandemic. A cross-sectional study was conducted among 1815 randomly selected chronic patients with common chronic diseases. A standardized WHOQOL BREF tool was used, and electronic data collection was employed with the kobo toolbox data collection server. Overall QoL and the domains of Health-Related Quality of life (HRQoL) were determined. Structural equation modelling was done to estimate independent variables' direct and indirect effects. Path coefficients with a 95% confidence interval were reported. About one in third, (33.35%) and 11.43% of the study participants had co-morbid conditions and identified complications, respectively. The mean score of QoL was 56.3 ranging from 14.59 and 98.95. The environmental domain was the most affected domain of HRQoL with a mean score of 52.18. Age, psychological, and environmental domains of HRQoL had a direct positive effect on the overall QoL while the physical and social relationships domains had an indirect positive effect. On the other hand, the number of medications taken, the presence of comorbidity, and complications had a direct negative impact on overall QoL. Furthermore, both rural residency and the presence of complications had an indirect negative effect on overall QoL via the mediator variables of environmental and physical health, respectively. The quality of life was compromised in chronic disease patients. During the COVID-19 pandemic, the environmental domain of HRQoL was the most affected. Several socio-demographic and clinical factors had an impact on QoL, either directly or indirectly. These findings highlighted the importance of paying special attention to rural residents, patients with complications, patients taking a higher number of medications, and patients with comorbidity.
doi_str_mv 10.1371/journal.pone.0278557
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subjects Acquired immune deficiency syndrome
AIDS
Biology and Life Sciences
Chronic Disease
Chronic diseases
Chronic illnesses
Comorbidity
Complications
Coronaviruses
COVID-19
COVID-19 - epidemiology
Cross-Sectional Studies
Data collection
Disease control
Disease prevention
Diseases
Domains
Epidemics
Ethiopia
Health aspects
Humans
Independent variables
Influence
Latent Class Analysis
Medicine and Health Sciences
Modelling
Multivariate statistical analysis
Pandemics
Patient outcomes
Patients
People and Places
Quality assessment
Quality of Life
Rural populations
Social Sciences
Structural equation modeling
title Quality of life among patients with the common chronic disease during COVID-19 pandemic in Northwest Ethiopia: A structural equation modelling
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