FcMBL magnetic bead-based MALDI-TOF MS rapidly identifies paediatric blood stream infections from positive blood cultures

Rapid identification of potentially life-threatening blood stream infections (BSI) improves clinical outcomes, yet conventional blood culture (BC) identification methods require ~24-72 hours of liquid culture, plus 24-48 hours to generate single colonies on solid media suitable for identification by...

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Veröffentlicht in:	PloS one 2022-11, Vol.17 (11), p.e0276777-e0276777
Hauptverfasser:	Kite, Kerry Anne, Loomba, Sahil, Elliott, Thomas J, Yongblah, Francis, Lightbown, Shanda L, Doyle, Thomas J, Gates, Lily, Alber, Dagmar, Downey, George A, McCurdy, Michael T, Hill, James A, Super, Michael, Ingber, Donald E, Klein, Nigel, Cloutman-Green, Elaine
Format:	Artikel
Sprache:	eng
Schlagworte:	Automation Bacteremia Bacteremia - diagnosis Bacteremia - microbiology Bacteria Bacterial infections Bacteriological Techniques - methods Beads Binding Biology and Life Sciences Blood Blood Culture Candidemia Carbon dioxide Centrifugation Child Diagnosis E coli Fungi Gram-negative bacteria Gram-Positive Bacteria Health aspects Humans Identification Identification methods Infections Inoculation Lectins Liquid culture Magnetic Phenomena Mannose Mannose-binding lectin Mass spectrometry Mass spectroscopy Medical examination Medicine and Health Sciences Pathogens Pediatrics Physical Sciences Proteins Research and Analysis Methods Sensitivity Sepsis Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization - methods Time-of-flight mass spectrometry Yeast
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