MicroRNA analysis in maternal blood of pregnancies with preterm premature rupture of membranes reveals a distinct expression profile

To determine the expression profile of microRNAs in the peripheral blood of pregnant women with preterm premature rupture of membranes (PPROM) compared to that of healthy pregnant women. This was a pilot study with case-control design in pregnant patients enrolled between January 2017 and June 2019....

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Veröffentlicht in:	PloS one 2022-11, Vol.17 (11), p.e0277098
Hauptverfasser:	Spiliopoulos, Michail, Haddad, Andrew, Al-Kouatly, Huda B, Haleema, Saeed, Paidas, Michael J, Iqbal, Sara N, Glazer, Robert I
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibiotics Blood Collagen Data collection Diabetes mellitus Diagnosis Extracellular matrix Female Fetal Membranes, Premature Rupture - genetics Fetuses Gene expression Genetic aspects Gestation Gestational Age Health aspects Humans Immune system Infant, Newborn Intravenous administration Matrix metalloproteinase Membranes Metalloproteinase MicroRNA MicroRNAs MicroRNAs - metabolism miRNA Obstetrical research Peripheral blood Pilot Projects Plasma Pre-eclampsia Preeclampsia Pregnancy Pregnancy complications Pregnancy, Multiple Premature rupture of membranes Ribonucleic acid RNA Rupture Statistical analysis Statistical significance
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