The interleukin-6/interleukin-23/T helper 17-axis as a driver of neuro-immune toxicity in the major neurocognitive psychosis or deficit schizophrenia: A precision nomothetic psychiatry analysis

Schizophrenia and especially deficit schizophrenia (DSCZ) are characterized by increased activity of neuroimmunotoxic pathways and a generalized cognitive decline (G-CoDe). There is no data on whether the interleukin (IL)-6/IL-23/T helper 17 (IL-6/IL-23/Th17)-axis is more associated with DSCZ than w...

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Veröffentlicht in:	PloS one 2022-10, Vol.17 (10), p.e0275839-e0275839
Hauptverfasser:	Al-Hakeim, Hussein Kadhem, Al-Musawi, Ali Fattah, Al-Mulla, Abbas, Al-Dujaili, Arafat Hussein, Debnath, Monojit, Maes, Michael
Format:	Artikel
Sprache:	eng
Schlagworte:	Alzheimer's disease Biology and Life Sciences Calcium Cognition Cognitive ability Copper Cytokines Diabetes Diagnosis G codes Genetic aspects Health aspects Helper cells Inflammation Inflammatory bowel disease Interleukin 10 Interleukin 17 Interleukin 21 Interleukin 22 Interleukin 23 Interleukin 6 Interleukins Lymphocytes T Magnesium Medicine and Health Sciences Memory Mental disorders Multiple sclerosis Physical Sciences Psychiatrists Psychiatry Psychological aspects Psychosis Rheumatoid arthritis Schizophrenia Semantics Toxicity Trace elements Tumor necrosis factor-α Zinc
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