An ACE2-dependent Sarbecovirus in Russian bats is resistant to SARS-CoV-2 vaccines

Spillover of sarbecoviruses from animals to humans has resulted in outbreaks of severe acute respiratory syndrome SARS-CoVs and the ongoing COVID-19 pandemic. Efforts to identify the origins of SARS-CoV-1 and -2 has resulted in the discovery of numerous animal sarbecoviruses–the majority of which ar...

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Veröffentlicht in:	PLoS pathogens 2022-09, Vol.18 (9), p.e1010828-e1010828
Hauptverfasser:	Seifert, Stephanie N, Bai, Shuangyi, Fawcett, Stephen, Norton, Elizabeth B, Zwezdaryk, Kevin J, Robinson, James, Gunn, Bronwyn, Letko, Michael
Format:	Artikel
Sprache:	eng
Schlagworte:	ACE2 Angiotensin converting enzyme Angiotensin-converting enzyme 2 Bats Biology and life sciences Coronaviruses COVID-19 Crystal structure Efficiency Experiments Global health Health aspects Health risks Infections Medicine and health sciences Monoclonal antibodies Pandemics Phylogenetics Public health Receptors Research and analysis methods Sarbecovirus Severe acute respiratory syndrome Severe acute respiratory syndrome coronavirus 2 Testing Tropism Vaccines Varieties Viral diseases Viral infections Viruses Wildlife
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