A GC-MC analysis of chemical compounds and identification of the antibacterial characteristics of the essential oil of two species exclusive to Iranian habitats: New chemotypes
The diversity found in the chemical compounds of a single species in different regions results in different biologic characteristics which can be considered as a strong source for identifying new chemotypes. Hymenocrater incanus Bunge and Dracocephalum kotschyi Boiss. are exclusive species of the La...
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| description | The diversity found in the chemical compounds of a single species in different regions results in different biologic characteristics which can be considered as a strong source for identifying new chemotypes. Hymenocrater incanus Bunge and Dracocephalum kotschyi Boiss. are exclusive species of the Lamiaceae family which grow in the western and central habitats of Iran. This study was designed and carried out to determine the yield, identify the chemical compounds, and evaluate the antimicrobial characteristics of the essential oil (EO) of these two species in Iran for the first time.
The flowering twigs of the species D. kotschyi and H. incanus were collected from the villages of Totmach and Kamu in Isfahan province respectively, in May 2019. The EO of these plants was extracted and separated using the water distillation method, utilizing the Clevenger device. The EO compounds were analyzed using a gas chromatograph coupled with a mass spectrometer (GC-MS). The evaluation of antimicrobial characteristics was carried out by determining the growth inhibition zone implementing the Agar method, the minimum inhibition concentration (MIC), and the minimum bactericidal/fungicidal concentration (MFC/MBC) utilizing liquid dilution culture.
The results indicated that the highest yield belonged to the EO of D. kotschyi at %2.6 (w/w). In this EO there were citral (%25.44), neral (%20.87), α-pinene (%14.48), trans-geranic acid methyl ester (%9.74), and D-limonene (%6.87). Moreover, H. incanus had the dominant compounds (-)-Spathulenol (%12.61), caryophyllene (%10.00), linolenic acid (%8.54), 1,8-cineole (%5.95), palmitic acid (%5.35), and α-cadinol (%5.17). The largest diameter of growth inhibition zone belonged to the H. incanus EO against the Gram-positive bacteria S. pyogenes (~17.67mm). The strongest inhibition activities in the form of growth inhibition diameter exhibited by the D. kotschyi EO were against the Gram-negative bacteria S. paratyphi-A serotype (~ 12 mm), K. pneumoniae, and Sh. dysenteriae (~ 11 mm) which was significant compared to the Gram-positive rifampin (~ 8 mm).
It can be seen that these species are new chemotypes with special and novel chemical compounds which can potentially be used to manufacture natural antibiotics against some bacterial strains. |
| doi_str_mv | 10.1371/journal.pone.0273987 |
| format | Article |
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The flowering twigs of the species D. kotschyi and H. incanus were collected from the villages of Totmach and Kamu in Isfahan province respectively, in May 2019. The EO of these plants was extracted and separated using the water distillation method, utilizing the Clevenger device. The EO compounds were analyzed using a gas chromatograph coupled with a mass spectrometer (GC-MS). The evaluation of antimicrobial characteristics was carried out by determining the growth inhibition zone implementing the Agar method, the minimum inhibition concentration (MIC), and the minimum bactericidal/fungicidal concentration (MFC/MBC) utilizing liquid dilution culture.
The results indicated that the highest yield belonged to the EO of D. kotschyi at %2.6 (w/w). In this EO there were citral (%25.44), neral (%20.87), α-pinene (%14.48), trans-geranic acid methyl ester (%9.74), and D-limonene (%6.87). Moreover, H. incanus had the dominant compounds (-)-Spathulenol (%12.61), caryophyllene (%10.00), linolenic acid (%8.54), 1,8-cineole (%5.95), palmitic acid (%5.35), and α-cadinol (%5.17). The largest diameter of growth inhibition zone belonged to the H. incanus EO against the Gram-positive bacteria S. pyogenes (~17.67mm). The strongest inhibition activities in the form of growth inhibition diameter exhibited by the D. kotschyi EO were against the Gram-negative bacteria S. paratyphi-A serotype (~ 12 mm), K. pneumoniae, and Sh. dysenteriae (~ 11 mm) which was significant compared to the Gram-positive rifampin (~ 8 mm).
It can be seen that these species are new chemotypes with special and novel chemical compounds which can potentially be used to manufacture natural antibiotics against some bacterial strains.</description><identifier>ISSN: 1932-6203</identifier><identifier>EISSN: 1932-6203</identifier><identifier>DOI: 10.1371/journal.pone.0273987</identifier><identifier>PMID: 36201544</identifier><language>eng</language><publisher>United States: Public Library of Science</publisher><subject>Acids ; Acyclic Monoterpenes ; Agar ; alpha-Linolenic Acid ; Anti-Bacterial Agents - chemistry ; Anti-Infective Agents - chemistry ; Antibacterial agents ; Antibiotics ; Antiinfectives and antibacterials ; Antimicrobial agents ; Bacteria ; Biological effects ; Biological Products ; Biology and Life Sciences ; Cadinol ; Caryophyllene ; Chemical compounds ; Chemical properties ; Cineole ; Citral ; Composition ; Dilution ; Distillation ; Distilled water ; Ecosystem ; Essences and essential oils ; Essential oils ; Esters ; Eucalyptol - analysis ; Flowering ; Fungicides ; Gas chromatography ; Gram-negative bacteria ; Gram-positive bacteria ; Health aspects ; Iran ; Lamiaceae - chemistry ; Limonene ; Linolenic acid ; Mass spectrometry ; Medicine ; Medicine and Health Sciences ; Methods ; Microbial Sensitivity Tests ; Minimum inhibitory concentration ; Neral ; Oils & fats ; Oils, Volatile - chemistry ; Palmitic Acid ; Physical Sciences ; Plant extracts ; Rifampin ; Saturated fatty acids ; Spathulenol ; Species ; Streptococcus infections ; Water - analysis ; α-Pinene</subject><ispartof>PloS one, 2022-10, Vol.17 (10), p.e0273987</ispartof><rights>COPYRIGHT 2022 Public Library of Science</rights><rights>2022 Mansureh Ghavam. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>2022 Mansureh Ghavam 2022 Mansureh Ghavam</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c622t-87511848c53a64aeafe8c6f6dc14237e349fb68a785d26a2fa655007d868c28a3</citedby><cites>FETCH-LOGICAL-c622t-87511848c53a64aeafe8c6f6dc14237e349fb68a785d26a2fa655007d868c28a3</cites><orcidid>0000-0002-8078-8664</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC9536594/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC9536594/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,860,881,2096,2915,23845,27901,27902,53766,53768,79343,79344</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/36201544$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><contributor>Nevárez-Moorillón, Guadalupe Virginia</contributor><creatorcontrib>Ghavam, Mansureh</creatorcontrib><title>A GC-MC analysis of chemical compounds and identification of the antibacterial characteristics of the essential oil of two species exclusive to Iranian habitats: New chemotypes</title><title>PloS one</title><addtitle>PLoS One</addtitle><description>The diversity found in the chemical compounds of a single species in different regions results in different biologic characteristics which can be considered as a strong source for identifying new chemotypes. Hymenocrater incanus Bunge and Dracocephalum kotschyi Boiss. are exclusive species of the Lamiaceae family which grow in the western and central habitats of Iran. This study was designed and carried out to determine the yield, identify the chemical compounds, and evaluate the antimicrobial characteristics of the essential oil (EO) of these two species in Iran for the first time.
The flowering twigs of the species D. kotschyi and H. incanus were collected from the villages of Totmach and Kamu in Isfahan province respectively, in May 2019. The EO of these plants was extracted and separated using the water distillation method, utilizing the Clevenger device. The EO compounds were analyzed using a gas chromatograph coupled with a mass spectrometer (GC-MS). The evaluation of antimicrobial characteristics was carried out by determining the growth inhibition zone implementing the Agar method, the minimum inhibition concentration (MIC), and the minimum bactericidal/fungicidal concentration (MFC/MBC) utilizing liquid dilution culture.
The results indicated that the highest yield belonged to the EO of D. kotschyi at %2.6 (w/w). In this EO there were citral (%25.44), neral (%20.87), α-pinene (%14.48), trans-geranic acid methyl ester (%9.74), and D-limonene (%6.87). Moreover, H. incanus had the dominant compounds (-)-Spathulenol (%12.61), caryophyllene (%10.00), linolenic acid (%8.54), 1,8-cineole (%5.95), palmitic acid (%5.35), and α-cadinol (%5.17). The largest diameter of growth inhibition zone belonged to the H. incanus EO against the Gram-positive bacteria S. pyogenes (~17.67mm). The strongest inhibition activities in the form of growth inhibition diameter exhibited by the D. kotschyi EO were against the Gram-negative bacteria S. paratyphi-A serotype (~ 12 mm), K. pneumoniae, and Sh. dysenteriae (~ 11 mm) which was significant compared to the Gram-positive rifampin (~ 8 mm).
It can be seen that these species are new chemotypes with special and novel chemical compounds which can potentially be used to manufacture natural antibiotics against some bacterial strains.</description><subject>Acids</subject><subject>Acyclic Monoterpenes</subject><subject>Agar</subject><subject>alpha-Linolenic Acid</subject><subject>Anti-Bacterial Agents - chemistry</subject><subject>Anti-Infective Agents - chemistry</subject><subject>Antibacterial agents</subject><subject>Antibiotics</subject><subject>Antiinfectives and antibacterials</subject><subject>Antimicrobial agents</subject><subject>Bacteria</subject><subject>Biological effects</subject><subject>Biological Products</subject><subject>Biology and Life Sciences</subject><subject>Cadinol</subject><subject>Caryophyllene</subject><subject>Chemical compounds</subject><subject>Chemical properties</subject><subject>Cineole</subject><subject>Citral</subject><subject>Composition</subject><subject>Dilution</subject><subject>Distillation</subject><subject>Distilled water</subject><subject>Ecosystem</subject><subject>Essences and essential oils</subject><subject>Essential oils</subject><subject>Esters</subject><subject>Eucalyptol - analysis</subject><subject>Flowering</subject><subject>Fungicides</subject><subject>Gas chromatography</subject><subject>Gram-negative bacteria</subject><subject>Gram-positive bacteria</subject><subject>Health aspects</subject><subject>Iran</subject><subject>Lamiaceae - chemistry</subject><subject>Limonene</subject><subject>Linolenic acid</subject><subject>Mass spectrometry</subject><subject>Medicine</subject><subject>Medicine and Health Sciences</subject><subject>Methods</subject><subject>Microbial Sensitivity Tests</subject><subject>Minimum inhibitory concentration</subject><subject>Neral</subject><subject>Oils & fats</subject><subject>Oils, Volatile - chemistry</subject><subject>Palmitic Acid</subject><subject>Physical Sciences</subject><subject>Plant extracts</subject><subject>Rifampin</subject><subject>Saturated fatty acids</subject><subject>Spathulenol</subject><subject>Species</subject><subject>Streptococcus infections</subject><subject>Water - analysis</subject><subject>α-Pinene</subject><issn>1932-6203</issn><issn>1932-6203</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><sourceid>DOA</sourceid><recordid>eNqNk9uO0zAQhiMEYpeFN0AQCQnBRUt8SOJwgVRVsFRaWInTrTVxJo1XaVwyzh7eikfE2barFu0FykXime__bU9moug5S6ZM5OzdhRv6Dtrp2nU4TXguCpU_iI5ZIfgk44l4uPd9FD0hukiSVKgsexwdiRBkqZTH0Z9ZfDqffJnHELxuyFLs6tg0uLIG2ti41doNXUUhXcW2ws7bOmS8dd0I-gZDxtsSjMfejooG-s2CvDW0g5Bo1AbA2fY2eOViWqOxSDFem3Yge4mxd_Gih85CFzdQWg-e3sdf8er2RM7frJGeRo9qaAmfbd8n0c9PH3_MP0_Ozk8X89nZxGSc-4nKU8aUVCYVkElAqFGZrM4qwyQXOQpZ1GWmIFdpxTPgNWRpmiR5pTJluAJxEr3c-K5bR3pbbNI855yrNC-KQCw2ROXgQq97u4L-Rjuw-jbg-qWGPhShRa3SsjKVRFljKUVeqBJUGTasUVYsFVnw-rDdbShXWJlQrB7aA9PDTGcbvXSXugjqtJDB4M3WoHe_BySvV5YMti106IbNuQVjacED-uof9P7bbaklhAvYrnZhXzOa6lnOWegfmY9e03uo8FRjB4XOrG2IHwjeHggC4_HaL2Eg0ovv3_6fPf91yL7eYxuE1jfk2mHsVDoE5QY0vSPqsb4rMkv0OFi7auhxsPR2sILsxf4PuhPtJkn8BY1MIHs</recordid><startdate>20221006</startdate><enddate>20221006</enddate><creator>Ghavam, Mansureh</creator><general>Public Library of Science</general><general>Public Library of Science (PLoS)</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>IOV</scope><scope>ISR</scope><scope>3V.</scope><scope>7QG</scope><scope>7QL</scope><scope>7QO</scope><scope>7RV</scope><scope>7SN</scope><scope>7SS</scope><scope>7T5</scope><scope>7TG</scope><scope>7TM</scope><scope>7U9</scope><scope>7X2</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FD</scope><scope>8FE</scope><scope>8FG</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABJCF</scope><scope>ABUWG</scope><scope>AEUYN</scope><scope>AFKRA</scope><scope>ARAPS</scope><scope>ATCPS</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>D1I</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB.</scope><scope>KB0</scope><scope>KL.</scope><scope>L6V</scope><scope>LK8</scope><scope>M0K</scope><scope>M0S</scope><scope>M1P</scope><scope>M7N</scope><scope>M7P</scope><scope>M7S</scope><scope>NAPCQ</scope><scope>P5Z</scope><scope>P62</scope><scope>P64</scope><scope>PATMY</scope><scope>PDBOC</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PTHSS</scope><scope>PYCSY</scope><scope>RC3</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope><orcidid>https://orcid.org/0000-0002-8078-8664</orcidid></search><sort><creationdate>20221006</creationdate><title>A GC-MC analysis of chemical compounds and identification of the antibacterial characteristics of the essential oil of two species exclusive to Iranian habitats: New chemotypes</title><author>Ghavam, Mansureh</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c622t-87511848c53a64aeafe8c6f6dc14237e349fb68a785d26a2fa655007d868c28a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Acids</topic><topic>Acyclic Monoterpenes</topic><topic>Agar</topic><topic>alpha-Linolenic Acid</topic><topic>Anti-Bacterial Agents - chemistry</topic><topic>Anti-Infective Agents - chemistry</topic><topic>Antibacterial agents</topic><topic>Antibiotics</topic><topic>Antiinfectives and antibacterials</topic><topic>Antimicrobial agents</topic><topic>Bacteria</topic><topic>Biological effects</topic><topic>Biological Products</topic><topic>Biology and Life Sciences</topic><topic>Cadinol</topic><topic>Caryophyllene</topic><topic>Chemical compounds</topic><topic>Chemical properties</topic><topic>Cineole</topic><topic>Citral</topic><topic>Composition</topic><topic>Dilution</topic><topic>Distillation</topic><topic>Distilled water</topic><topic>Ecosystem</topic><topic>Essences and essential oils</topic><topic>Essential oils</topic><topic>Esters</topic><topic>Eucalyptol - analysis</topic><topic>Flowering</topic><topic>Fungicides</topic><topic>Gas chromatography</topic><topic>Gram-negative bacteria</topic><topic>Gram-positive bacteria</topic><topic>Health aspects</topic><topic>Iran</topic><topic>Lamiaceae - chemistry</topic><topic>Limonene</topic><topic>Linolenic acid</topic><topic>Mass spectrometry</topic><topic>Medicine</topic><topic>Medicine and Health Sciences</topic><topic>Methods</topic><topic>Microbial Sensitivity Tests</topic><topic>Minimum inhibitory concentration</topic><topic>Neral</topic><topic>Oils & fats</topic><topic>Oils, Volatile - chemistry</topic><topic>Palmitic Acid</topic><topic>Physical Sciences</topic><topic>Plant extracts</topic><topic>Rifampin</topic><topic>Saturated fatty acids</topic><topic>Spathulenol</topic><topic>Species</topic><topic>Streptococcus infections</topic><topic>Water - analysis</topic><topic>α-Pinene</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ghavam, Mansureh</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Opposing Viewpoints in Context (Gale)</collection><collection>Gale In Context: Science</collection><collection>ProQuest Central (Corporate)</collection><collection>Animal Behavior Abstracts</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Biotechnology Research Abstracts</collection><collection>Nursing & Allied Health Database</collection><collection>Ecology Abstracts</collection><collection>Entomology Abstracts (Full archive)</collection><collection>Immunology Abstracts</collection><collection>Meteorological & Geoastrophysical Abstracts</collection><collection>Nucleic Acids Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Agricultural Science Collection</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Technology Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Materials Science & Engineering Collection</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest One Sustainability</collection><collection>ProQuest Central UK/Ireland</collection><collection>Advanced Technologies & Aerospace Collection</collection><collection>Agricultural & Environmental Science Collection</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Technology Collection</collection><collection>Natural Science Collection</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Materials Science Collection</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Materials Science Database</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Meteorological & Geoastrophysical Abstracts - 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Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>DOAJ Directory of Open Access Journals</collection><jtitle>PloS one</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ghavam, Mansureh</au><au>Nevárez-Moorillón, Guadalupe Virginia</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A GC-MC analysis of chemical compounds and identification of the antibacterial characteristics of the essential oil of two species exclusive to Iranian habitats: New chemotypes</atitle><jtitle>PloS one</jtitle><addtitle>PLoS One</addtitle><date>2022-10-06</date><risdate>2022</risdate><volume>17</volume><issue>10</issue><spage>e0273987</spage><pages>e0273987-</pages><issn>1932-6203</issn><eissn>1932-6203</eissn><abstract>The diversity found in the chemical compounds of a single species in different regions results in different biologic characteristics which can be considered as a strong source for identifying new chemotypes. Hymenocrater incanus Bunge and Dracocephalum kotschyi Boiss. are exclusive species of the Lamiaceae family which grow in the western and central habitats of Iran. This study was designed and carried out to determine the yield, identify the chemical compounds, and evaluate the antimicrobial characteristics of the essential oil (EO) of these two species in Iran for the first time.
The flowering twigs of the species D. kotschyi and H. incanus were collected from the villages of Totmach and Kamu in Isfahan province respectively, in May 2019. The EO of these plants was extracted and separated using the water distillation method, utilizing the Clevenger device. The EO compounds were analyzed using a gas chromatograph coupled with a mass spectrometer (GC-MS). The evaluation of antimicrobial characteristics was carried out by determining the growth inhibition zone implementing the Agar method, the minimum inhibition concentration (MIC), and the minimum bactericidal/fungicidal concentration (MFC/MBC) utilizing liquid dilution culture.
The results indicated that the highest yield belonged to the EO of D. kotschyi at %2.6 (w/w). In this EO there were citral (%25.44), neral (%20.87), α-pinene (%14.48), trans-geranic acid methyl ester (%9.74), and D-limonene (%6.87). Moreover, H. incanus had the dominant compounds (-)-Spathulenol (%12.61), caryophyllene (%10.00), linolenic acid (%8.54), 1,8-cineole (%5.95), palmitic acid (%5.35), and α-cadinol (%5.17). The largest diameter of growth inhibition zone belonged to the H. incanus EO against the Gram-positive bacteria S. pyogenes (~17.67mm). The strongest inhibition activities in the form of growth inhibition diameter exhibited by the D. kotschyi EO were against the Gram-negative bacteria S. paratyphi-A serotype (~ 12 mm), K. pneumoniae, and Sh. dysenteriae (~ 11 mm) which was significant compared to the Gram-positive rifampin (~ 8 mm).
It can be seen that these species are new chemotypes with special and novel chemical compounds which can potentially be used to manufacture natural antibiotics against some bacterial strains.</abstract><cop>United States</cop><pub>Public Library of Science</pub><pmid>36201544</pmid><doi>10.1371/journal.pone.0273987</doi><tpages>e0273987</tpages><orcidid>https://orcid.org/0000-0002-8078-8664</orcidid><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1932-6203 |
| ispartof | PloS one, 2022-10, Vol.17 (10), p.e0273987 |
| issn | 1932-6203 1932-6203 |
| language | eng |
| recordid | cdi_plos_journals_2722285799 |
| source | Public Library of Science (PLoS) Journals Open Access; MEDLINE; DOAJ Directory of Open Access Journals; EZB-FREE-00999 freely available EZB journals; PubMed Central; Free Full-Text Journals in Chemistry |
| subjects | Acids Acyclic Monoterpenes Agar alpha-Linolenic Acid Anti-Bacterial Agents - chemistry Anti-Infective Agents - chemistry Antibacterial agents Antibiotics Antiinfectives and antibacterials Antimicrobial agents Bacteria Biological effects Biological Products Biology and Life Sciences Cadinol Caryophyllene Chemical compounds Chemical properties Cineole Citral Composition Dilution Distillation Distilled water Ecosystem Essences and essential oils Essential oils Esters Eucalyptol - analysis Flowering Fungicides Gas chromatography Gram-negative bacteria Gram-positive bacteria Health aspects Iran Lamiaceae - chemistry Limonene Linolenic acid Mass spectrometry Medicine Medicine and Health Sciences Methods Microbial Sensitivity Tests Minimum inhibitory concentration Neral Oils & fats Oils, Volatile - chemistry Palmitic Acid Physical Sciences Plant extracts Rifampin Saturated fatty acids Spathulenol Species Streptococcus infections Water - analysis α-Pinene |
| title | A GC-MC analysis of chemical compounds and identification of the antibacterial characteristics of the essential oil of two species exclusive to Iranian habitats: New chemotypes |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-29T01%3A51%3A05IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_plos_&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=A%20GC-MC%20analysis%20of%20chemical%20compounds%20and%20identification%20of%20the%20antibacterial%20characteristics%20of%20the%20essential%20oil%20of%20two%20species%20exclusive%20to%20Iranian%20habitats:%20New%20chemotypes&rft.jtitle=PloS%20one&rft.au=Ghavam,%20Mansureh&rft.date=2022-10-06&rft.volume=17&rft.issue=10&rft.spage=e0273987&rft.pages=e0273987-&rft.issn=1932-6203&rft.eissn=1932-6203&rft_id=info:doi/10.1371/journal.pone.0273987&rft_dat=%3Cgale_plos_%3EA721201472%3C/gale_plos_%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2722285799&rft_id=info:pmid/36201544&rft_galeid=A721201472&rft_doaj_id=oai_doaj_org_article_85bdcd4e4feb43798ba8b655fe4d1536&rfr_iscdi=true |