Pharmacological investigations of effort-based decision-making in humans: Naltrexone and nicotine

Many mental health disorders are characterized by an impaired ability, or willingness, to exert effort to obtain rewards. This impairment is modeled in effort-based decision tasks, and neuropharmacological studies implicate dopamine in this process. However, other transmitter systems such as opioide...

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Veröffentlicht in:	PloS one 2022-10, Vol.17 (10), p.e0275027-e0275027
Hauptverfasser:	Nunez, Cecilia, Hoots, Jennifer K, Schepers, Scott T, Bower, Michael, de Wit, Harriet, Wardle, Margaret C
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute effects Biology and Life Sciences Birth control Cholinergics Decision making Dopamine Dosage and administration Drug therapy Drugs Expenditures Health aspects Medicine and Health Sciences Mental health Mental illness Mental task performance Methods Naltrexone Narcotics Nicotine Physical Sciences Placebos Probability Reinforcement Reward (Psychology) Social Sciences
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