Is there a place for a molecular diagnostic test for pelvic inflammatory disease in primary care? An exploratory qualitative study
There is currently no test for pelvic inflammatory disease (PID) that is non-invasive and sufficiently sensitive and specific. Clinicians must therefore diagnose PID clinically, ruling out medical emergencies and conducting pelvic examinations where possible. While guidelines state that clinicians s...
Gespeichert in:
| Veröffentlicht in: | PloS one 2022-09, Vol.17 (9), p.e0274666-e0274666 |
|---|---|
| Hauptverfasser: | , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | e0274666 |
|---|---|
| container_issue | 9 |
| container_start_page | e0274666 |
| container_title | PloS one |
| container_volume | 17 |
| creator | Bittleston, Helen Hocking, Jane S Goller, Jane L Coombe, Jacqueline Bateson, Deborah Sweeney, Sally Fleming, Kirsteen Huston, Wilhelmina M |
| description | There is currently no test for pelvic inflammatory disease (PID) that is non-invasive and sufficiently sensitive and specific. Clinicians must therefore diagnose PID clinically, ruling out medical emergencies and conducting pelvic examinations where possible. While guidelines state that clinicians should be prepared to over-diagnose PID, it remains an under-diagnosed condition, with severe reproductive health impacts when left untreated. This research is the first to consider the perspectives of end-users on the development of a diagnostic test for PID. Semi-structured live video feed online (Zoom) interviews were conducted with 11 clinicians and nine women (aged 18-30 years) in Australia to understand how a diagnostic test might be used, and what characteristics a test would need for it to be acceptable to clinicians and young women. Participants were recruited via researcher and university student networks. Reflexive thematic analysis was used to identify key themes relating to the acceptability and characteristics of a diagnostic test for PID. Seven general practitioners, four clinicians working in sexual health clinics, and nine young women (aged 21-27 years) were interviewed. Clinicians were aged between 31-58 years and were predominantly female. Clinicians recognised that the development of an accurate test to diagnose PID would be valuable to themselves and other clinicians, particularly those who lack experience diagnosing PID, and those working in certain settings, including emergency departments. They discussed how they might use a test to enhance their clinical assessment but highlighted that it would not replace clinical judgement. Clinicians also considered how a test would impact the patient experience and time to treatment, emphasising that it should be minimally invasive and have a quick turnaround time. Young women said a test would be acceptable if endorsed by a trustworthy clinician. PID remains a challenging diagnosis. Development of a minimally invasive and sufficiently accurate diagnostic test would be acceptable to young women and benefit some clinicians, although no test would completely replace an experienced clinician's judgement in making a PID diagnosis. |
| doi_str_mv | 10.1371/journal.pone.0274666 |
| format | Article |
| fullrecord | <record><control><sourceid>gale_plos_</sourceid><recordid>TN_cdi_plos_journals_2715763209</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A718366129</galeid><doaj_id>oai_doaj_org_article_6c993c5f368e4cc4ad03a793dee35a14</doaj_id><sourcerecordid>A718366129</sourcerecordid><originalsourceid>FETCH-LOGICAL-c599t-8b699da7f3adf582c99da1013248d6cb435a2ff163368d83b39e851c49e032713</originalsourceid><addsrcrecordid>eNqNk0tr3DAQx01padK036BQQ6G0h91ali1bl5Ql9LEQCPR1FbPyeFeLbG0keUmu_eSdzbolLjkUHyTN_PSfhzVJ8pJlc8Yr9n7rBt-Dne9cj_MsrwohxKPklEmez0Se8cf39ifJsxC2WVbyWoinyQkXLGeV5KfJr2VI4wY9ppDuLGhMW-dp3zmLerDg08bAunchGp1GDPHOv0O7p7PpWwtdB9H5W-ICQkAypjtvOiCTBo8f0kWf4s3OOn_krgewJkI0e0xDHJrb58mTFmzAF-N6lvz49PH7xZfZ5dXn5cXicqZLKeOsXgkpG6haDk1b1rk-nFjGeF7UjdCrgpeQty0TnIu6qfmKS6xLpguJGc8rxs-SV0ddyiWosX1BkausBM8zScTySDQOtmqsQjkw6s7g_FqBp0ZYVILCc122FAsLrQtoMg7U0QaR8mAFaZ2P0YZVh43GPnqwE9GppzcbtXZ7JYu6oBpI4O0o4N31QJ1XnQkarYUe3TDmLbO8rgl9_Q_6cHUjtQYqgP6do7j6IKoWFau5oEdxoOYPUPQ12BlNb601ZJ9ceDe5QEzEm7iGIQS1_Pb1_9mrn1P2zT12g2DjJjg7ROP6MAWLI6i9C8Fj-7fJLFOHUfnTDXUYFTWOCv8NZlgF-g</addsrcrecordid><sourcetype>Open Website</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2715763209</pqid></control><display><type>article</type><title>Is there a place for a molecular diagnostic test for pelvic inflammatory disease in primary care? An exploratory qualitative study</title><source>PLoS</source><source>Directory of Open Access Journals</source><source>PubMed (Medline)</source><source>Free Full-Text Journals in Chemistry</source><source>EZB Electronic Journals Library</source><creator>Bittleston, Helen ; Hocking, Jane S ; Goller, Jane L ; Coombe, Jacqueline ; Bateson, Deborah ; Sweeney, Sally ; Fleming, Kirsteen ; Huston, Wilhelmina M</creator><contributor>Fuller, Sebastian S</contributor><creatorcontrib>Bittleston, Helen ; Hocking, Jane S ; Goller, Jane L ; Coombe, Jacqueline ; Bateson, Deborah ; Sweeney, Sally ; Fleming, Kirsteen ; Huston, Wilhelmina M ; Fuller, Sebastian S</creatorcontrib><description>There is currently no test for pelvic inflammatory disease (PID) that is non-invasive and sufficiently sensitive and specific. Clinicians must therefore diagnose PID clinically, ruling out medical emergencies and conducting pelvic examinations where possible. While guidelines state that clinicians should be prepared to over-diagnose PID, it remains an under-diagnosed condition, with severe reproductive health impacts when left untreated. This research is the first to consider the perspectives of end-users on the development of a diagnostic test for PID. Semi-structured live video feed online (Zoom) interviews were conducted with 11 clinicians and nine women (aged 18-30 years) in Australia to understand how a diagnostic test might be used, and what characteristics a test would need for it to be acceptable to clinicians and young women. Participants were recruited via researcher and university student networks. Reflexive thematic analysis was used to identify key themes relating to the acceptability and characteristics of a diagnostic test for PID. Seven general practitioners, four clinicians working in sexual health clinics, and nine young women (aged 21-27 years) were interviewed. Clinicians were aged between 31-58 years and were predominantly female. Clinicians recognised that the development of an accurate test to diagnose PID would be valuable to themselves and other clinicians, particularly those who lack experience diagnosing PID, and those working in certain settings, including emergency departments. They discussed how they might use a test to enhance their clinical assessment but highlighted that it would not replace clinical judgement. Clinicians also considered how a test would impact the patient experience and time to treatment, emphasising that it should be minimally invasive and have a quick turnaround time. Young women said a test would be acceptable if endorsed by a trustworthy clinician. PID remains a challenging diagnosis. Development of a minimally invasive and sufficiently accurate diagnostic test would be acceptable to young women and benefit some clinicians, although no test would completely replace an experienced clinician's judgement in making a PID diagnosis.</description><identifier>ISSN: 1932-6203</identifier><identifier>EISSN: 1932-6203</identifier><identifier>DOI: 10.1371/journal.pone.0274666</identifier><identifier>PMID: 36121793</identifier><language>eng</language><publisher>San Francisco: Public Library of Science</publisher><subject>Acceptability ; Complications and side effects ; Consent ; Diagnosis ; Diagnostic systems ; Diagnostic tests ; Emergency medical care ; Emergency medical services ; Ethics ; Health aspects ; Health care ; Health risks ; Infertility ; Inflammatory diseases ; Interviews ; Medical diagnosis ; Medicine and Health Sciences ; Molecular diagnostic techniques ; Ovaries ; Pelvic inflammatory disease ; Pelvic pain ; People and Places ; Pregnancy complications ; Primary care ; Qualitative research ; Reproductive health ; Research and Analysis Methods ; Sexual health ; Statistics ; Teenage girls ; Womens health</subject><ispartof>PloS one, 2022-09, Vol.17 (9), p.e0274666-e0274666</ispartof><rights>COPYRIGHT 2022 Public Library of Science</rights><rights>2022 Bittleston et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>2022 Bittleston et al 2022 Bittleston et al</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c599t-8b699da7f3adf582c99da1013248d6cb435a2ff163368d83b39e851c49e032713</citedby><cites>FETCH-LOGICAL-c599t-8b699da7f3adf582c99da1013248d6cb435a2ff163368d83b39e851c49e032713</cites><orcidid>0000-0002-2586-2403 ; 0000-0002-5768-3223</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC9484633/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC9484633/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,315,728,781,785,865,886,2103,2929,23871,27929,27930,53796,53798</link.rule.ids></links><search><contributor>Fuller, Sebastian S</contributor><creatorcontrib>Bittleston, Helen</creatorcontrib><creatorcontrib>Hocking, Jane S</creatorcontrib><creatorcontrib>Goller, Jane L</creatorcontrib><creatorcontrib>Coombe, Jacqueline</creatorcontrib><creatorcontrib>Bateson, Deborah</creatorcontrib><creatorcontrib>Sweeney, Sally</creatorcontrib><creatorcontrib>Fleming, Kirsteen</creatorcontrib><creatorcontrib>Huston, Wilhelmina M</creatorcontrib><title>Is there a place for a molecular diagnostic test for pelvic inflammatory disease in primary care? An exploratory qualitative study</title><title>PloS one</title><description>There is currently no test for pelvic inflammatory disease (PID) that is non-invasive and sufficiently sensitive and specific. Clinicians must therefore diagnose PID clinically, ruling out medical emergencies and conducting pelvic examinations where possible. While guidelines state that clinicians should be prepared to over-diagnose PID, it remains an under-diagnosed condition, with severe reproductive health impacts when left untreated. This research is the first to consider the perspectives of end-users on the development of a diagnostic test for PID. Semi-structured live video feed online (Zoom) interviews were conducted with 11 clinicians and nine women (aged 18-30 years) in Australia to understand how a diagnostic test might be used, and what characteristics a test would need for it to be acceptable to clinicians and young women. Participants were recruited via researcher and university student networks. Reflexive thematic analysis was used to identify key themes relating to the acceptability and characteristics of a diagnostic test for PID. Seven general practitioners, four clinicians working in sexual health clinics, and nine young women (aged 21-27 years) were interviewed. Clinicians were aged between 31-58 years and were predominantly female. Clinicians recognised that the development of an accurate test to diagnose PID would be valuable to themselves and other clinicians, particularly those who lack experience diagnosing PID, and those working in certain settings, including emergency departments. They discussed how they might use a test to enhance their clinical assessment but highlighted that it would not replace clinical judgement. Clinicians also considered how a test would impact the patient experience and time to treatment, emphasising that it should be minimally invasive and have a quick turnaround time. Young women said a test would be acceptable if endorsed by a trustworthy clinician. PID remains a challenging diagnosis. Development of a minimally invasive and sufficiently accurate diagnostic test would be acceptable to young women and benefit some clinicians, although no test would completely replace an experienced clinician's judgement in making a PID diagnosis.</description><subject>Acceptability</subject><subject>Complications and side effects</subject><subject>Consent</subject><subject>Diagnosis</subject><subject>Diagnostic systems</subject><subject>Diagnostic tests</subject><subject>Emergency medical care</subject><subject>Emergency medical services</subject><subject>Ethics</subject><subject>Health aspects</subject><subject>Health care</subject><subject>Health risks</subject><subject>Infertility</subject><subject>Inflammatory diseases</subject><subject>Interviews</subject><subject>Medical diagnosis</subject><subject>Medicine and Health Sciences</subject><subject>Molecular diagnostic techniques</subject><subject>Ovaries</subject><subject>Pelvic inflammatory disease</subject><subject>Pelvic pain</subject><subject>People and Places</subject><subject>Pregnancy complications</subject><subject>Primary care</subject><subject>Qualitative research</subject><subject>Reproductive health</subject><subject>Research and Analysis Methods</subject><subject>Sexual health</subject><subject>Statistics</subject><subject>Teenage girls</subject><subject>Womens health</subject><issn>1932-6203</issn><issn>1932-6203</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>DOA</sourceid><recordid>eNqNk0tr3DAQx01padK036BQQ6G0h91ali1bl5Ql9LEQCPR1FbPyeFeLbG0keUmu_eSdzbolLjkUHyTN_PSfhzVJ8pJlc8Yr9n7rBt-Dne9cj_MsrwohxKPklEmez0Se8cf39ifJsxC2WVbyWoinyQkXLGeV5KfJr2VI4wY9ppDuLGhMW-dp3zmLerDg08bAunchGp1GDPHOv0O7p7PpWwtdB9H5W-ICQkAypjtvOiCTBo8f0kWf4s3OOn_krgewJkI0e0xDHJrb58mTFmzAF-N6lvz49PH7xZfZ5dXn5cXicqZLKeOsXgkpG6haDk1b1rk-nFjGeF7UjdCrgpeQty0TnIu6qfmKS6xLpguJGc8rxs-SV0ddyiWosX1BkausBM8zScTySDQOtmqsQjkw6s7g_FqBp0ZYVILCc122FAsLrQtoMg7U0QaR8mAFaZ2P0YZVh43GPnqwE9GppzcbtXZ7JYu6oBpI4O0o4N31QJ1XnQkarYUe3TDmLbO8rgl9_Q_6cHUjtQYqgP6do7j6IKoWFau5oEdxoOYPUPQ12BlNb601ZJ9ceDe5QEzEm7iGIQS1_Pb1_9mrn1P2zT12g2DjJjg7ROP6MAWLI6i9C8Fj-7fJLFOHUfnTDXUYFTWOCv8NZlgF-g</recordid><startdate>20220919</startdate><enddate>20220919</enddate><creator>Bittleston, Helen</creator><creator>Hocking, Jane S</creator><creator>Goller, Jane L</creator><creator>Coombe, Jacqueline</creator><creator>Bateson, Deborah</creator><creator>Sweeney, Sally</creator><creator>Fleming, Kirsteen</creator><creator>Huston, Wilhelmina M</creator><general>Public Library of Science</general><general>Public Library of Science (PLoS)</general><scope>AAYXX</scope><scope>CITATION</scope><scope>IOV</scope><scope>ISR</scope><scope>3V.</scope><scope>7QG</scope><scope>7QL</scope><scope>7QO</scope><scope>7RV</scope><scope>7SN</scope><scope>7SS</scope><scope>7T5</scope><scope>7TG</scope><scope>7TM</scope><scope>7U9</scope><scope>7X2</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FD</scope><scope>8FE</scope><scope>8FG</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABJCF</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>ARAPS</scope><scope>ATCPS</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>D1I</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB.</scope><scope>KB0</scope><scope>KL.</scope><scope>L6V</scope><scope>LK8</scope><scope>M0K</scope><scope>M0S</scope><scope>M1P</scope><scope>M7N</scope><scope>M7P</scope><scope>M7S</scope><scope>NAPCQ</scope><scope>P5Z</scope><scope>P62</scope><scope>P64</scope><scope>PATMY</scope><scope>PDBOC</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PTHSS</scope><scope>PYCSY</scope><scope>RC3</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope><orcidid>https://orcid.org/0000-0002-2586-2403</orcidid><orcidid>https://orcid.org/0000-0002-5768-3223</orcidid></search><sort><creationdate>20220919</creationdate><title>Is there a place for a molecular diagnostic test for pelvic inflammatory disease in primary care? An exploratory qualitative study</title><author>Bittleston, Helen ; Hocking, Jane S ; Goller, Jane L ; Coombe, Jacqueline ; Bateson, Deborah ; Sweeney, Sally ; Fleming, Kirsteen ; Huston, Wilhelmina M</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c599t-8b699da7f3adf582c99da1013248d6cb435a2ff163368d83b39e851c49e032713</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Acceptability</topic><topic>Complications and side effects</topic><topic>Consent</topic><topic>Diagnosis</topic><topic>Diagnostic systems</topic><topic>Diagnostic tests</topic><topic>Emergency medical care</topic><topic>Emergency medical services</topic><topic>Ethics</topic><topic>Health aspects</topic><topic>Health care</topic><topic>Health risks</topic><topic>Infertility</topic><topic>Inflammatory diseases</topic><topic>Interviews</topic><topic>Medical diagnosis</topic><topic>Medicine and Health Sciences</topic><topic>Molecular diagnostic techniques</topic><topic>Ovaries</topic><topic>Pelvic inflammatory disease</topic><topic>Pelvic pain</topic><topic>People and Places</topic><topic>Pregnancy complications</topic><topic>Primary care</topic><topic>Qualitative research</topic><topic>Reproductive health</topic><topic>Research and Analysis Methods</topic><topic>Sexual health</topic><topic>Statistics</topic><topic>Teenage girls</topic><topic>Womens health</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Bittleston, Helen</creatorcontrib><creatorcontrib>Hocking, Jane S</creatorcontrib><creatorcontrib>Goller, Jane L</creatorcontrib><creatorcontrib>Coombe, Jacqueline</creatorcontrib><creatorcontrib>Bateson, Deborah</creatorcontrib><creatorcontrib>Sweeney, Sally</creatorcontrib><creatorcontrib>Fleming, Kirsteen</creatorcontrib><creatorcontrib>Huston, Wilhelmina M</creatorcontrib><collection>CrossRef</collection><collection>Opposing Viewpoints In Context</collection><collection>Gale in Context: Science</collection><collection>ProQuest Central (Corporate)</collection><collection>Animal Behavior Abstracts</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Biotechnology Research Abstracts</collection><collection>ProQuest Nursing and Allied Health Journals</collection><collection>Ecology Abstracts</collection><collection>Entomology Abstracts (Full archive)</collection><collection>Immunology Abstracts</collection><collection>Meteorological & Geoastrophysical Abstracts</collection><collection>Nucleic Acids Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Agricultural Science Collection</collection><collection>ProQuest Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Technology Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Materials Science & Engineering Collection</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central UK/Ireland</collection><collection>Advanced Technologies & Aerospace Database (1962 - current)</collection><collection>Agricultural & Environmental Science Collection</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Technology Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Materials Science Collection</collection><collection>ProQuest Central</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>SciTech Premium Collection (Proquest) (PQ_SDU_P3)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>ProQuest Materials Science Database</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Meteorological & Geoastrophysical Abstracts - Academic</collection><collection>ProQuest Engineering Collection</collection><collection>ProQuest Biological Science Collection</collection><collection>Agriculture Science Database</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>PML(ProQuest Medical Library)</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>ProQuest Biological Science Journals</collection><collection>ProQuest Engineering Database</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest Advanced Technologies & Aerospace Database</collection><collection>ProQuest Advanced Technologies & Aerospace Collection</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Environmental Science Database</collection><collection>Materials science collection</collection><collection>Access via ProQuest (Open Access)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>Engineering collection</collection><collection>Environmental Science Collection</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>Directory of Open Access Journals</collection><jtitle>PloS one</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Bittleston, Helen</au><au>Hocking, Jane S</au><au>Goller, Jane L</au><au>Coombe, Jacqueline</au><au>Bateson, Deborah</au><au>Sweeney, Sally</au><au>Fleming, Kirsteen</au><au>Huston, Wilhelmina M</au><au>Fuller, Sebastian S</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Is there a place for a molecular diagnostic test for pelvic inflammatory disease in primary care? An exploratory qualitative study</atitle><jtitle>PloS one</jtitle><date>2022-09-19</date><risdate>2022</risdate><volume>17</volume><issue>9</issue><spage>e0274666</spage><epage>e0274666</epage><pages>e0274666-e0274666</pages><issn>1932-6203</issn><eissn>1932-6203</eissn><abstract>There is currently no test for pelvic inflammatory disease (PID) that is non-invasive and sufficiently sensitive and specific. Clinicians must therefore diagnose PID clinically, ruling out medical emergencies and conducting pelvic examinations where possible. While guidelines state that clinicians should be prepared to over-diagnose PID, it remains an under-diagnosed condition, with severe reproductive health impacts when left untreated. This research is the first to consider the perspectives of end-users on the development of a diagnostic test for PID. Semi-structured live video feed online (Zoom) interviews were conducted with 11 clinicians and nine women (aged 18-30 years) in Australia to understand how a diagnostic test might be used, and what characteristics a test would need for it to be acceptable to clinicians and young women. Participants were recruited via researcher and university student networks. Reflexive thematic analysis was used to identify key themes relating to the acceptability and characteristics of a diagnostic test for PID. Seven general practitioners, four clinicians working in sexual health clinics, and nine young women (aged 21-27 years) were interviewed. Clinicians were aged between 31-58 years and were predominantly female. Clinicians recognised that the development of an accurate test to diagnose PID would be valuable to themselves and other clinicians, particularly those who lack experience diagnosing PID, and those working in certain settings, including emergency departments. They discussed how they might use a test to enhance their clinical assessment but highlighted that it would not replace clinical judgement. Clinicians also considered how a test would impact the patient experience and time to treatment, emphasising that it should be minimally invasive and have a quick turnaround time. Young women said a test would be acceptable if endorsed by a trustworthy clinician. PID remains a challenging diagnosis. Development of a minimally invasive and sufficiently accurate diagnostic test would be acceptable to young women and benefit some clinicians, although no test would completely replace an experienced clinician's judgement in making a PID diagnosis.</abstract><cop>San Francisco</cop><pub>Public Library of Science</pub><pmid>36121793</pmid><doi>10.1371/journal.pone.0274666</doi><tpages>e0274666</tpages><orcidid>https://orcid.org/0000-0002-2586-2403</orcidid><orcidid>https://orcid.org/0000-0002-5768-3223</orcidid><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1932-6203 |
| ispartof | PloS one, 2022-09, Vol.17 (9), p.e0274666-e0274666 |
| issn | 1932-6203 1932-6203 |
| language | eng |
| recordid | cdi_plos_journals_2715763209 |
| source | PLoS; Directory of Open Access Journals; PubMed (Medline); Free Full-Text Journals in Chemistry; EZB Electronic Journals Library |
| subjects | Acceptability Complications and side effects Consent Diagnosis Diagnostic systems Diagnostic tests Emergency medical care Emergency medical services Ethics Health aspects Health care Health risks Infertility Inflammatory diseases Interviews Medical diagnosis Medicine and Health Sciences Molecular diagnostic techniques Ovaries Pelvic inflammatory disease Pelvic pain People and Places Pregnancy complications Primary care Qualitative research Reproductive health Research and Analysis Methods Sexual health Statistics Teenage girls Womens health |
| title | Is there a place for a molecular diagnostic test for pelvic inflammatory disease in primary care? An exploratory qualitative study |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-13T22%3A06%3A51IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_plos_&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Is%20there%20a%20place%20for%20a%20molecular%20diagnostic%20test%20for%20pelvic%20inflammatory%20disease%20in%20primary%20care?%20An%20exploratory%20qualitative%20study&rft.jtitle=PloS%20one&rft.au=Bittleston,%20Helen&rft.date=2022-09-19&rft.volume=17&rft.issue=9&rft.spage=e0274666&rft.epage=e0274666&rft.pages=e0274666-e0274666&rft.issn=1932-6203&rft.eissn=1932-6203&rft_id=info:doi/10.1371/journal.pone.0274666&rft_dat=%3Cgale_plos_%3EA718366129%3C/gale_plos_%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2715763209&rft_id=info:pmid/36121793&rft_galeid=A718366129&rft_doaj_id=oai_doaj_org_article_6c993c5f368e4cc4ad03a793dee35a14&rfr_iscdi=true |