Archetypal Analysis for population genetics

The estimation of genetic clusters using genomic data has application from genome-wide association studies (GWAS) to demographic history to polygenic risk scores (PRS) and is expected to play an important role in the analyses of increasingly diverse, large-scale cohorts. However, existing methods ar...

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Veröffentlicht in:	PLoS computational biology 2022-08, Vol.18 (8), p.e1010301-e1010301
Hauptverfasser:	Gimbernat-Mayol, Julia, Dominguez Mantes, Albert, Bustamante, Carlos D, Mas Montserrat, Daniel, Ioannidis, Alexander G
Format:	Artikel
Sprache:	eng
Schlagworte:	Approximation Biology and Life Sciences Clusters Computer applications Computing time Decomposition Genetics Genome-wide association studies Genomes Genotype & phenotype Labels Optimization People and Places Physical Sciences Population genetics Research and Analysis Methods Visualization
Online-Zugang:	Volltext
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