Correlation of alpha-1 antitrypsin levels and exosome associated neutrophil elastase endothelial injury in subjects with SARS-CoV2 infection

Background Severe acute respiratory syndrome caused by a novel coronavirus 2 (SARS-CoV-2) has infected more than 18 million people worldwide. The activation of endothelial cells is a hallmark of signs of SARS-CoV-2 infection that includes altered integrity of vessel barrier and endothelial inflammat...

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Veröffentlicht in:	PloS one 2022-09, Vol.17 (9), p.e0274427-e0274427
Hauptverfasser:	Lascano, Jorge, Oshins, Regina, Eagan, Christina, Wadood, Zerka, Qiang, Xiao, Flagg, Tammy, Scindia, Yogesh, Mehrad, Borna, Brantly, Mark, Khodayari, Nazli
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute respiratory distress syndrome Alpha 1-antitrypsin Biology and Life Sciences Care and treatment Cell activation Consent Coronaviruses Correlation Cytokines Diagnosis Disease Elastase Endothelial cells Exosomes Extracellular matrix Health aspects Homeostasis Infections Inflammation Laboratories Leukocytes (neutrophilic) Lung diseases Medicine and Health Sciences Neutrophils Permeability Plasma Plasma levels Respiratory diseases Severe acute respiratory syndrome Severe acute respiratory syndrome coronavirus 2 Sterilization Therapeutic targets Viral diseases
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