Aedes koreicus, a vector on the rise: Pan-European genetic patterns, mitochondrial and draft genome sequencing
The mosquito Aedes koreicus (Edwards, 1917) is a recent invader on the European continent that was introduced to several new places since its first detection in 2008. Compared to other exotic Aedes mosquitoes with public health significance that invaded Europe during the last decades, this species&#...
Gespeichert in:
| Veröffentlicht in: | PloS one 2022-08, Vol.17 (8), p.e0269880-e0269880 |
|---|---|
| Hauptverfasser: | , , , , , , , , , , , , , , , , , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | e0269880 |
|---|---|
| container_issue | 8 |
| container_start_page | e0269880 |
| container_title | PloS one |
| container_volume | 17 |
| creator | Kurucz, Kornélia Zeghbib, Safia Arnoldi, Daniele Marini, Giovanni Manica, Mattia Michelutti, Alice Montarsi, Fabrizio Deblauwe, Isra Van Bortel, Wim Smitz, Nathalie Pfitzner, Wolf Peter Czajka, Christina Jöst, Artur Kalan, Katja Susnjar, Jana Ivovic, Vladimir Kuczmog, Anett Lanszki, Zsófia Tóth, Gábor Endre Somogyi, Balázs A Herczeg, Róbert Urbán, Péter Bueno-Marí, Rubén Soltész, Zoltán Kemenesi, Gábor |
| description | The mosquito Aedes koreicus (Edwards, 1917) is a recent invader on the European continent that was introduced to several new places since its first detection in 2008. Compared to other exotic Aedes mosquitoes with public health significance that invaded Europe during the last decades, this species' biology, behavior, and dispersal patterns were poorly investigated to date. To understand the species' population relationships and dispersal patterns within Europe, a fragment of the cytochrome oxidase I (COI or COX1) gene was sequenced from 130 mosquitoes, collected from five countries where the species has been introduced and/or established. Oxford Nanopore and Illumina sequencing techniques were combined to generate the first complete nuclear and mitochondrial genomic sequences of Ae. koreicus from the European region. The complete genome of Ae. koreicus is 879 Mb. COI haplotype analyses identified five major groups (altogether 31 different haplotypes) and revealed a large-scale dispersal pattern between European Ae. koreicus populations. Continuous admixture of populations from Belgium, Italy, and Hungary was highlighted, additionally, haplotype diversity and clustering indicate a separation of German sequences from other populations, pointing to an independent introduction of Ae. koreicus to Europe. Finally, a genetic expansion signal was identified, suggesting the species might be present in more locations than currently detected. Our results highlight the importance of genetic research of invasive mosquitoes to understand general dispersal patterns, reveal main dispersal routes and form the baseline of future mitigation actions. The first complete genomic sequence also provides a significant leap in the general understanding of this species, opening the possibility for future genome-related studies, such as the detection of 'Single Nucleotide Polymorphism' markers. Considering its public health importance, it is crucial to further investigate the species' population genetic dynamic, including a larger sampling and additional genomic markers. |
| doi_str_mv | 10.1371/journal.pone.0269880 |
| format | Article |
| fullrecord | <record><control><sourceid>gale_plos_</sourceid><recordid>TN_cdi_plos_journals_2697076589</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A712207290</galeid><doaj_id>oai_doaj_org_article_65bde42931d345ce96dcc6e4b58a89e4</doaj_id><sourcerecordid>A712207290</sourcerecordid><originalsourceid>FETCH-LOGICAL-c669t-7ea34cc3cfe903da647c7e5d2ef7ff74bdde4937187e14e9313526dfd02ba773</originalsourceid><addsrcrecordid>eNqNk1GL1DAUhYso7jr6DwQDgig4Y5q0SeODMCyrDiys6OJryCS3naxtMibpov_ejFNlK_sgeWi4_e45vYfeonha4lVJefnm2o_BqX619w5WmDDRNPhecVoKSpaMYHr_1v2keBTjNcY1bRh7WJzQWpRUiOq0cGswENE3H8DqMb5GCt2ATj4g71DaAQo2wlv0Sbnl-Rj8HpRDHThIVqO9SgmCy02DTV7vvDPBqh4pZ5AJqk0H0g-AInwfwWnrusfFg1b1EZ5Mz0Vx9f786uzj8uLyw-ZsfbHUjIm05KBopTXVLQhMjWIV1xxqQ6DlbcurrTFQiZxCw6GsQNCS1oSZ1mCyVZzTRfHsKLvvfZRTUlHmkDjmrG5EJjZHwnh1LffBDir8lF5Z-bvgQydVyEP2IFm9zW4kmxha1RoEM1ozqLZ1oxoBVdZ6N7mN2wGMBpeC6mei8zfO7mTnb6SgFeElyQIvJ4Hgc1IxycFGDX2vHPhx-m5BMKcZff4Pevd0E9WpPIB1rc---iAq19kwK5Gc66JY3UHlY2CwOv9Wrc31WcOrWUNmEvxInRpjlJsvn_-fvfw6Z1_cYneg-rSLvh-T9S7OweoI6uBjDND-DbnE8rAVf9KQh62Q01bQXy61_pI</addsrcrecordid><sourcetype>Open Website</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2697076589</pqid></control><display><type>article</type><title>Aedes koreicus, a vector on the rise: Pan-European genetic patterns, mitochondrial and draft genome sequencing</title><source>Public Library of Science (PLoS) Journals Open Access</source><source>DOAJ Directory of Open Access Journals</source><source>EZB-FREE-00999 freely available EZB journals</source><source>PubMed Central</source><source>Free Full-Text Journals in Chemistry</source><creator>Kurucz, Kornélia ; Zeghbib, Safia ; Arnoldi, Daniele ; Marini, Giovanni ; Manica, Mattia ; Michelutti, Alice ; Montarsi, Fabrizio ; Deblauwe, Isra ; Van Bortel, Wim ; Smitz, Nathalie ; Pfitzner, Wolf Peter ; Czajka, Christina ; Jöst, Artur ; Kalan, Katja ; Susnjar, Jana ; Ivovic, Vladimir ; Kuczmog, Anett ; Lanszki, Zsófia ; Tóth, Gábor Endre ; Somogyi, Balázs A ; Herczeg, Róbert ; Urbán, Péter ; Bueno-Marí, Rubén ; Soltész, Zoltán ; Kemenesi, Gábor</creator><creatorcontrib>Kurucz, Kornélia ; Zeghbib, Safia ; Arnoldi, Daniele ; Marini, Giovanni ; Manica, Mattia ; Michelutti, Alice ; Montarsi, Fabrizio ; Deblauwe, Isra ; Van Bortel, Wim ; Smitz, Nathalie ; Pfitzner, Wolf Peter ; Czajka, Christina ; Jöst, Artur ; Kalan, Katja ; Susnjar, Jana ; Ivovic, Vladimir ; Kuczmog, Anett ; Lanszki, Zsófia ; Tóth, Gábor Endre ; Somogyi, Balázs A ; Herczeg, Róbert ; Urbán, Péter ; Bueno-Marí, Rubén ; Soltész, Zoltán ; Kemenesi, Gábor</creatorcontrib><description>The mosquito Aedes koreicus (Edwards, 1917) is a recent invader on the European continent that was introduced to several new places since its first detection in 2008. Compared to other exotic Aedes mosquitoes with public health significance that invaded Europe during the last decades, this species' biology, behavior, and dispersal patterns were poorly investigated to date. To understand the species' population relationships and dispersal patterns within Europe, a fragment of the cytochrome oxidase I (COI or COX1) gene was sequenced from 130 mosquitoes, collected from five countries where the species has been introduced and/or established. Oxford Nanopore and Illumina sequencing techniques were combined to generate the first complete nuclear and mitochondrial genomic sequences of Ae. koreicus from the European region. The complete genome of Ae. koreicus is 879 Mb. COI haplotype analyses identified five major groups (altogether 31 different haplotypes) and revealed a large-scale dispersal pattern between European Ae. koreicus populations. Continuous admixture of populations from Belgium, Italy, and Hungary was highlighted, additionally, haplotype diversity and clustering indicate a separation of German sequences from other populations, pointing to an independent introduction of Ae. koreicus to Europe. Finally, a genetic expansion signal was identified, suggesting the species might be present in more locations than currently detected. Our results highlight the importance of genetic research of invasive mosquitoes to understand general dispersal patterns, reveal main dispersal routes and form the baseline of future mitigation actions. The first complete genomic sequence also provides a significant leap in the general understanding of this species, opening the possibility for future genome-related studies, such as the detection of 'Single Nucleotide Polymorphism' markers. Considering its public health importance, it is crucial to further investigate the species' population genetic dynamic, including a larger sampling and additional genomic markers.</description><identifier>ISSN: 1932-6203</identifier><identifier>EISSN: 1932-6203</identifier><identifier>DOI: 10.1371/journal.pone.0269880</identifier><identifier>PMID: 35913994</identifier><language>eng</language><publisher>San Francisco: Public Library of Science</publisher><subject>Acids ; Aedes ; Analysis ; Aquatic insects ; Biology and Life Sciences ; Clustering ; Culicidae ; Cytochrome ; Cytochrome oxidase I ; Cytochromes ; Dispersal ; Dispersion ; DNA sequencing ; Earth Sciences ; Ecology and Environmental Sciences ; Gene sequencing ; Genetic aspects ; Genomes ; Genomics ; Haplotypes ; Introduced species ; Invasive insects ; Laboratories ; Markers ; Medicine and Health Sciences ; Mitigation ; Mitochondria ; Mosquitoes ; Nucleotide sequencing ; Nucleotides ; People and Places ; Phylogeography ; Polymorphism ; Population ; Population genetics ; Populations ; Public health ; Single-nucleotide polymorphism</subject><ispartof>PloS one, 2022-08, Vol.17 (8), p.e0269880-e0269880</ispartof><rights>COPYRIGHT 2022 Public Library of Science</rights><rights>2022 Kurucz et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>2022 Kurucz et al 2022 Kurucz et al</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c669t-7ea34cc3cfe903da647c7e5d2ef7ff74bdde4937187e14e9313526dfd02ba773</citedby><cites>FETCH-LOGICAL-c669t-7ea34cc3cfe903da647c7e5d2ef7ff74bdde4937187e14e9313526dfd02ba773</cites><orcidid>0000-0002-5004-5763 ; 0000-0001-6940-8934 ; 0000-0002-1287-697X ; 0000-0001-8969-7382 ; 0000-0002-4650-2300 ; 0000-0002-5903-0082 ; 0000-0001-5155-0801 ; 0000-0003-2817-5278 ; 0000-0003-4043-3428 ; 0000-0001-6190-1265 ; 0000-0002-6644-518X ; 0000-0002-8886-3315 ; 0000-0001-7268-8965 ; 0000-0003-3116-4633 ; 0000-0001-9775-3065 ; 0000-0002-4898-8519 ; 0000-0003-3423-9258 ; 0000-0001-9603-7489 ; 0000-0003-3709-1199 ; 0000-0001-9721-7211 ; 0000-0002-1562-9528</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC9342712/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC9342712/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,860,881,2096,2915,23845,27901,27902,53766,53768,79342,79343</link.rule.ids></links><search><creatorcontrib>Kurucz, Kornélia</creatorcontrib><creatorcontrib>Zeghbib, Safia</creatorcontrib><creatorcontrib>Arnoldi, Daniele</creatorcontrib><creatorcontrib>Marini, Giovanni</creatorcontrib><creatorcontrib>Manica, Mattia</creatorcontrib><creatorcontrib>Michelutti, Alice</creatorcontrib><creatorcontrib>Montarsi, Fabrizio</creatorcontrib><creatorcontrib>Deblauwe, Isra</creatorcontrib><creatorcontrib>Van Bortel, Wim</creatorcontrib><creatorcontrib>Smitz, Nathalie</creatorcontrib><creatorcontrib>Pfitzner, Wolf Peter</creatorcontrib><creatorcontrib>Czajka, Christina</creatorcontrib><creatorcontrib>Jöst, Artur</creatorcontrib><creatorcontrib>Kalan, Katja</creatorcontrib><creatorcontrib>Susnjar, Jana</creatorcontrib><creatorcontrib>Ivovic, Vladimir</creatorcontrib><creatorcontrib>Kuczmog, Anett</creatorcontrib><creatorcontrib>Lanszki, Zsófia</creatorcontrib><creatorcontrib>Tóth, Gábor Endre</creatorcontrib><creatorcontrib>Somogyi, Balázs A</creatorcontrib><creatorcontrib>Herczeg, Róbert</creatorcontrib><creatorcontrib>Urbán, Péter</creatorcontrib><creatorcontrib>Bueno-Marí, Rubén</creatorcontrib><creatorcontrib>Soltész, Zoltán</creatorcontrib><creatorcontrib>Kemenesi, Gábor</creatorcontrib><title>Aedes koreicus, a vector on the rise: Pan-European genetic patterns, mitochondrial and draft genome sequencing</title><title>PloS one</title><description>The mosquito Aedes koreicus (Edwards, 1917) is a recent invader on the European continent that was introduced to several new places since its first detection in 2008. Compared to other exotic Aedes mosquitoes with public health significance that invaded Europe during the last decades, this species' biology, behavior, and dispersal patterns were poorly investigated to date. To understand the species' population relationships and dispersal patterns within Europe, a fragment of the cytochrome oxidase I (COI or COX1) gene was sequenced from 130 mosquitoes, collected from five countries where the species has been introduced and/or established. Oxford Nanopore and Illumina sequencing techniques were combined to generate the first complete nuclear and mitochondrial genomic sequences of Ae. koreicus from the European region. The complete genome of Ae. koreicus is 879 Mb. COI haplotype analyses identified five major groups (altogether 31 different haplotypes) and revealed a large-scale dispersal pattern between European Ae. koreicus populations. Continuous admixture of populations from Belgium, Italy, and Hungary was highlighted, additionally, haplotype diversity and clustering indicate a separation of German sequences from other populations, pointing to an independent introduction of Ae. koreicus to Europe. Finally, a genetic expansion signal was identified, suggesting the species might be present in more locations than currently detected. Our results highlight the importance of genetic research of invasive mosquitoes to understand general dispersal patterns, reveal main dispersal routes and form the baseline of future mitigation actions. The first complete genomic sequence also provides a significant leap in the general understanding of this species, opening the possibility for future genome-related studies, such as the detection of 'Single Nucleotide Polymorphism' markers. Considering its public health importance, it is crucial to further investigate the species' population genetic dynamic, including a larger sampling and additional genomic markers.</description><subject>Acids</subject><subject>Aedes</subject><subject>Analysis</subject><subject>Aquatic insects</subject><subject>Biology and Life Sciences</subject><subject>Clustering</subject><subject>Culicidae</subject><subject>Cytochrome</subject><subject>Cytochrome oxidase I</subject><subject>Cytochromes</subject><subject>Dispersal</subject><subject>Dispersion</subject><subject>DNA sequencing</subject><subject>Earth Sciences</subject><subject>Ecology and Environmental Sciences</subject><subject>Gene sequencing</subject><subject>Genetic aspects</subject><subject>Genomes</subject><subject>Genomics</subject><subject>Haplotypes</subject><subject>Introduced species</subject><subject>Invasive insects</subject><subject>Laboratories</subject><subject>Markers</subject><subject>Medicine and Health Sciences</subject><subject>Mitigation</subject><subject>Mitochondria</subject><subject>Mosquitoes</subject><subject>Nucleotide sequencing</subject><subject>Nucleotides</subject><subject>People and Places</subject><subject>Phylogeography</subject><subject>Polymorphism</subject><subject>Population</subject><subject>Population genetics</subject><subject>Populations</subject><subject>Public health</subject><subject>Single-nucleotide polymorphism</subject><issn>1932-6203</issn><issn>1932-6203</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><sourceid>BENPR</sourceid><sourceid>DOA</sourceid><recordid>eNqNk1GL1DAUhYso7jr6DwQDgig4Y5q0SeODMCyrDiys6OJryCS3naxtMibpov_ejFNlK_sgeWi4_e45vYfeonha4lVJefnm2o_BqX619w5WmDDRNPhecVoKSpaMYHr_1v2keBTjNcY1bRh7WJzQWpRUiOq0cGswENE3H8DqMb5GCt2ATj4g71DaAQo2wlv0Sbnl-Rj8HpRDHThIVqO9SgmCy02DTV7vvDPBqh4pZ5AJqk0H0g-AInwfwWnrusfFg1b1EZ5Mz0Vx9f786uzj8uLyw-ZsfbHUjIm05KBopTXVLQhMjWIV1xxqQ6DlbcurrTFQiZxCw6GsQNCS1oSZ1mCyVZzTRfHsKLvvfZRTUlHmkDjmrG5EJjZHwnh1LffBDir8lF5Z-bvgQydVyEP2IFm9zW4kmxha1RoEM1ozqLZ1oxoBVdZ6N7mN2wGMBpeC6mei8zfO7mTnb6SgFeElyQIvJ4Hgc1IxycFGDX2vHPhx-m5BMKcZff4Pevd0E9WpPIB1rc---iAq19kwK5Gc66JY3UHlY2CwOv9Wrc31WcOrWUNmEvxInRpjlJsvn_-fvfw6Z1_cYneg-rSLvh-T9S7OweoI6uBjDND-DbnE8rAVf9KQh62Q01bQXy61_pI</recordid><startdate>20220801</startdate><enddate>20220801</enddate><creator>Kurucz, Kornélia</creator><creator>Zeghbib, Safia</creator><creator>Arnoldi, Daniele</creator><creator>Marini, Giovanni</creator><creator>Manica, Mattia</creator><creator>Michelutti, Alice</creator><creator>Montarsi, Fabrizio</creator><creator>Deblauwe, Isra</creator><creator>Van Bortel, Wim</creator><creator>Smitz, Nathalie</creator><creator>Pfitzner, Wolf Peter</creator><creator>Czajka, Christina</creator><creator>Jöst, Artur</creator><creator>Kalan, Katja</creator><creator>Susnjar, Jana</creator><creator>Ivovic, Vladimir</creator><creator>Kuczmog, Anett</creator><creator>Lanszki, Zsófia</creator><creator>Tóth, Gábor Endre</creator><creator>Somogyi, Balázs A</creator><creator>Herczeg, Róbert</creator><creator>Urbán, Péter</creator><creator>Bueno-Marí, Rubén</creator><creator>Soltész, Zoltán</creator><creator>Kemenesi, Gábor</creator><general>Public Library of Science</general><general>Public Library of Science (PLoS)</general><scope>AAYXX</scope><scope>CITATION</scope><scope>IOV</scope><scope>ISR</scope><scope>3V.</scope><scope>7QG</scope><scope>7QL</scope><scope>7QO</scope><scope>7RV</scope><scope>7SN</scope><scope>7SS</scope><scope>7T5</scope><scope>7TG</scope><scope>7TM</scope><scope>7U9</scope><scope>7X2</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FD</scope><scope>8FE</scope><scope>8FG</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABJCF</scope><scope>ABUWG</scope><scope>AEUYN</scope><scope>AFKRA</scope><scope>ARAPS</scope><scope>ATCPS</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>D1I</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB.</scope><scope>KB0</scope><scope>KL.</scope><scope>L6V</scope><scope>LK8</scope><scope>M0K</scope><scope>M0S</scope><scope>M1P</scope><scope>M7N</scope><scope>M7P</scope><scope>M7S</scope><scope>NAPCQ</scope><scope>P5Z</scope><scope>P62</scope><scope>P64</scope><scope>PATMY</scope><scope>PDBOC</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PTHSS</scope><scope>PYCSY</scope><scope>RC3</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope><orcidid>https://orcid.org/0000-0002-5004-5763</orcidid><orcidid>https://orcid.org/0000-0001-6940-8934</orcidid><orcidid>https://orcid.org/0000-0002-1287-697X</orcidid><orcidid>https://orcid.org/0000-0001-8969-7382</orcidid><orcidid>https://orcid.org/0000-0002-4650-2300</orcidid><orcidid>https://orcid.org/0000-0002-5903-0082</orcidid><orcidid>https://orcid.org/0000-0001-5155-0801</orcidid><orcidid>https://orcid.org/0000-0003-2817-5278</orcidid><orcidid>https://orcid.org/0000-0003-4043-3428</orcidid><orcidid>https://orcid.org/0000-0001-6190-1265</orcidid><orcidid>https://orcid.org/0000-0002-6644-518X</orcidid><orcidid>https://orcid.org/0000-0002-8886-3315</orcidid><orcidid>https://orcid.org/0000-0001-7268-8965</orcidid><orcidid>https://orcid.org/0000-0003-3116-4633</orcidid><orcidid>https://orcid.org/0000-0001-9775-3065</orcidid><orcidid>https://orcid.org/0000-0002-4898-8519</orcidid><orcidid>https://orcid.org/0000-0003-3423-9258</orcidid><orcidid>https://orcid.org/0000-0001-9603-7489</orcidid><orcidid>https://orcid.org/0000-0003-3709-1199</orcidid><orcidid>https://orcid.org/0000-0001-9721-7211</orcidid><orcidid>https://orcid.org/0000-0002-1562-9528</orcidid></search><sort><creationdate>20220801</creationdate><title>Aedes koreicus, a vector on the rise: Pan-European genetic patterns, mitochondrial and draft genome sequencing</title><author>Kurucz, Kornélia ; Zeghbib, Safia ; Arnoldi, Daniele ; Marini, Giovanni ; Manica, Mattia ; Michelutti, Alice ; Montarsi, Fabrizio ; Deblauwe, Isra ; Van Bortel, Wim ; Smitz, Nathalie ; Pfitzner, Wolf Peter ; Czajka, Christina ; Jöst, Artur ; Kalan, Katja ; Susnjar, Jana ; Ivovic, Vladimir ; Kuczmog, Anett ; Lanszki, Zsófia ; Tóth, Gábor Endre ; Somogyi, Balázs A ; Herczeg, Róbert ; Urbán, Péter ; Bueno-Marí, Rubén ; Soltész, Zoltán ; Kemenesi, Gábor</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c669t-7ea34cc3cfe903da647c7e5d2ef7ff74bdde4937187e14e9313526dfd02ba773</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Acids</topic><topic>Aedes</topic><topic>Analysis</topic><topic>Aquatic insects</topic><topic>Biology and Life Sciences</topic><topic>Clustering</topic><topic>Culicidae</topic><topic>Cytochrome</topic><topic>Cytochrome oxidase I</topic><topic>Cytochromes</topic><topic>Dispersal</topic><topic>Dispersion</topic><topic>DNA sequencing</topic><topic>Earth Sciences</topic><topic>Ecology and Environmental Sciences</topic><topic>Gene sequencing</topic><topic>Genetic aspects</topic><topic>Genomes</topic><topic>Genomics</topic><topic>Haplotypes</topic><topic>Introduced species</topic><topic>Invasive insects</topic><topic>Laboratories</topic><topic>Markers</topic><topic>Medicine and Health Sciences</topic><topic>Mitigation</topic><topic>Mitochondria</topic><topic>Mosquitoes</topic><topic>Nucleotide sequencing</topic><topic>Nucleotides</topic><topic>People and Places</topic><topic>Phylogeography</topic><topic>Polymorphism</topic><topic>Population</topic><topic>Population genetics</topic><topic>Populations</topic><topic>Public health</topic><topic>Single-nucleotide polymorphism</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kurucz, Kornélia</creatorcontrib><creatorcontrib>Zeghbib, Safia</creatorcontrib><creatorcontrib>Arnoldi, Daniele</creatorcontrib><creatorcontrib>Marini, Giovanni</creatorcontrib><creatorcontrib>Manica, Mattia</creatorcontrib><creatorcontrib>Michelutti, Alice</creatorcontrib><creatorcontrib>Montarsi, Fabrizio</creatorcontrib><creatorcontrib>Deblauwe, Isra</creatorcontrib><creatorcontrib>Van Bortel, Wim</creatorcontrib><creatorcontrib>Smitz, Nathalie</creatorcontrib><creatorcontrib>Pfitzner, Wolf Peter</creatorcontrib><creatorcontrib>Czajka, Christina</creatorcontrib><creatorcontrib>Jöst, Artur</creatorcontrib><creatorcontrib>Kalan, Katja</creatorcontrib><creatorcontrib>Susnjar, Jana</creatorcontrib><creatorcontrib>Ivovic, Vladimir</creatorcontrib><creatorcontrib>Kuczmog, Anett</creatorcontrib><creatorcontrib>Lanszki, Zsófia</creatorcontrib><creatorcontrib>Tóth, Gábor Endre</creatorcontrib><creatorcontrib>Somogyi, Balázs A</creatorcontrib><creatorcontrib>Herczeg, Róbert</creatorcontrib><creatorcontrib>Urbán, Péter</creatorcontrib><creatorcontrib>Bueno-Marí, Rubén</creatorcontrib><creatorcontrib>Soltész, Zoltán</creatorcontrib><creatorcontrib>Kemenesi, Gábor</creatorcontrib><collection>CrossRef</collection><collection>Gale In Context: Opposing Viewpoints</collection><collection>Gale In Context: Science</collection><collection>ProQuest Central (Corporate)</collection><collection>Animal Behavior Abstracts</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Biotechnology Research Abstracts</collection><collection>Nursing & Allied Health Database</collection><collection>Ecology Abstracts</collection><collection>Entomology Abstracts (Full archive)</collection><collection>Immunology Abstracts</collection><collection>Meteorological & Geoastrophysical Abstracts</collection><collection>Nucleic Acids Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Agricultural Science Collection</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Technology Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Materials Science & Engineering Collection</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest One Sustainability</collection><collection>ProQuest Central UK/Ireland</collection><collection>Advanced Technologies & Aerospace Collection</collection><collection>Agricultural & Environmental Science Collection</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Technology Collection (ProQuest)</collection><collection>Natural Science Collection (ProQuest)</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Materials Science Collection</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Materials Science Database</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Meteorological & Geoastrophysical Abstracts - Academic</collection><collection>ProQuest Engineering Collection</collection><collection>ProQuest Biological Science Collection</collection><collection>Agricultural Science Database</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biological Science Database</collection><collection>Engineering Database</collection><collection>Nursing & Allied Health Premium</collection><collection>Advanced Technologies & Aerospace Database</collection><collection>ProQuest Advanced Technologies & Aerospace Collection</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Environmental Science Database</collection><collection>Materials Science Collection</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>Engineering Collection</collection><collection>Environmental Science Collection</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>DOAJ Directory of Open Access Journals</collection><jtitle>PloS one</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kurucz, Kornélia</au><au>Zeghbib, Safia</au><au>Arnoldi, Daniele</au><au>Marini, Giovanni</au><au>Manica, Mattia</au><au>Michelutti, Alice</au><au>Montarsi, Fabrizio</au><au>Deblauwe, Isra</au><au>Van Bortel, Wim</au><au>Smitz, Nathalie</au><au>Pfitzner, Wolf Peter</au><au>Czajka, Christina</au><au>Jöst, Artur</au><au>Kalan, Katja</au><au>Susnjar, Jana</au><au>Ivovic, Vladimir</au><au>Kuczmog, Anett</au><au>Lanszki, Zsófia</au><au>Tóth, Gábor Endre</au><au>Somogyi, Balázs A</au><au>Herczeg, Róbert</au><au>Urbán, Péter</au><au>Bueno-Marí, Rubén</au><au>Soltész, Zoltán</au><au>Kemenesi, Gábor</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Aedes koreicus, a vector on the rise: Pan-European genetic patterns, mitochondrial and draft genome sequencing</atitle><jtitle>PloS one</jtitle><date>2022-08-01</date><risdate>2022</risdate><volume>17</volume><issue>8</issue><spage>e0269880</spage><epage>e0269880</epage><pages>e0269880-e0269880</pages><issn>1932-6203</issn><eissn>1932-6203</eissn><abstract>The mosquito Aedes koreicus (Edwards, 1917) is a recent invader on the European continent that was introduced to several new places since its first detection in 2008. Compared to other exotic Aedes mosquitoes with public health significance that invaded Europe during the last decades, this species' biology, behavior, and dispersal patterns were poorly investigated to date. To understand the species' population relationships and dispersal patterns within Europe, a fragment of the cytochrome oxidase I (COI or COX1) gene was sequenced from 130 mosquitoes, collected from five countries where the species has been introduced and/or established. Oxford Nanopore and Illumina sequencing techniques were combined to generate the first complete nuclear and mitochondrial genomic sequences of Ae. koreicus from the European region. The complete genome of Ae. koreicus is 879 Mb. COI haplotype analyses identified five major groups (altogether 31 different haplotypes) and revealed a large-scale dispersal pattern between European Ae. koreicus populations. Continuous admixture of populations from Belgium, Italy, and Hungary was highlighted, additionally, haplotype diversity and clustering indicate a separation of German sequences from other populations, pointing to an independent introduction of Ae. koreicus to Europe. Finally, a genetic expansion signal was identified, suggesting the species might be present in more locations than currently detected. Our results highlight the importance of genetic research of invasive mosquitoes to understand general dispersal patterns, reveal main dispersal routes and form the baseline of future mitigation actions. The first complete genomic sequence also provides a significant leap in the general understanding of this species, opening the possibility for future genome-related studies, such as the detection of 'Single Nucleotide Polymorphism' markers. Considering its public health importance, it is crucial to further investigate the species' population genetic dynamic, including a larger sampling and additional genomic markers.</abstract><cop>San Francisco</cop><pub>Public Library of Science</pub><pmid>35913994</pmid><doi>10.1371/journal.pone.0269880</doi><tpages>e0269880</tpages><orcidid>https://orcid.org/0000-0002-5004-5763</orcidid><orcidid>https://orcid.org/0000-0001-6940-8934</orcidid><orcidid>https://orcid.org/0000-0002-1287-697X</orcidid><orcidid>https://orcid.org/0000-0001-8969-7382</orcidid><orcidid>https://orcid.org/0000-0002-4650-2300</orcidid><orcidid>https://orcid.org/0000-0002-5903-0082</orcidid><orcidid>https://orcid.org/0000-0001-5155-0801</orcidid><orcidid>https://orcid.org/0000-0003-2817-5278</orcidid><orcidid>https://orcid.org/0000-0003-4043-3428</orcidid><orcidid>https://orcid.org/0000-0001-6190-1265</orcidid><orcidid>https://orcid.org/0000-0002-6644-518X</orcidid><orcidid>https://orcid.org/0000-0002-8886-3315</orcidid><orcidid>https://orcid.org/0000-0001-7268-8965</orcidid><orcidid>https://orcid.org/0000-0003-3116-4633</orcidid><orcidid>https://orcid.org/0000-0001-9775-3065</orcidid><orcidid>https://orcid.org/0000-0002-4898-8519</orcidid><orcidid>https://orcid.org/0000-0003-3423-9258</orcidid><orcidid>https://orcid.org/0000-0001-9603-7489</orcidid><orcidid>https://orcid.org/0000-0003-3709-1199</orcidid><orcidid>https://orcid.org/0000-0001-9721-7211</orcidid><orcidid>https://orcid.org/0000-0002-1562-9528</orcidid><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1932-6203 |
| ispartof | PloS one, 2022-08, Vol.17 (8), p.e0269880-e0269880 |
| issn | 1932-6203 1932-6203 |
| language | eng |
| recordid | cdi_plos_journals_2697076589 |
| source | Public Library of Science (PLoS) Journals Open Access; DOAJ Directory of Open Access Journals; EZB-FREE-00999 freely available EZB journals; PubMed Central; Free Full-Text Journals in Chemistry |
| subjects | Acids Aedes Analysis Aquatic insects Biology and Life Sciences Clustering Culicidae Cytochrome Cytochrome oxidase I Cytochromes Dispersal Dispersion DNA sequencing Earth Sciences Ecology and Environmental Sciences Gene sequencing Genetic aspects Genomes Genomics Haplotypes Introduced species Invasive insects Laboratories Markers Medicine and Health Sciences Mitigation Mitochondria Mosquitoes Nucleotide sequencing Nucleotides People and Places Phylogeography Polymorphism Population Population genetics Populations Public health Single-nucleotide polymorphism |
| title | Aedes koreicus, a vector on the rise: Pan-European genetic patterns, mitochondrial and draft genome sequencing |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-07T23%3A13%3A03IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_plos_&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Aedes%20koreicus,%20a%20vector%20on%20the%20rise:%20Pan-European%20genetic%20patterns,%20mitochondrial%20and%20draft%20genome%20sequencing&rft.jtitle=PloS%20one&rft.au=Kurucz,%20Korn%C3%A9lia&rft.date=2022-08-01&rft.volume=17&rft.issue=8&rft.spage=e0269880&rft.epage=e0269880&rft.pages=e0269880-e0269880&rft.issn=1932-6203&rft.eissn=1932-6203&rft_id=info:doi/10.1371/journal.pone.0269880&rft_dat=%3Cgale_plos_%3EA712207290%3C/gale_plos_%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2697076589&rft_id=info:pmid/35913994&rft_galeid=A712207290&rft_doaj_id=oai_doaj_org_article_65bde42931d345ce96dcc6e4b58a89e4&rfr_iscdi=true |