Molecular characterization of gastric adenocarcinoma diagnosed in patients previously treated for Hodgkin lymphoma or testicular cancer

The risk of developing gastric cancer is increased in patients treated with radiotherapy for Hodgkin lymphoma (HL) or testicular cancer (TC). This study aims to assess if gastric adenocarcinoma after treatment for HL/TC (t-GC) is molecularly different from gastric adenocarcinoma in the general popul...

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Veröffentlicht in:	PloS one 2022-07, Vol.17 (7), p.e0270591-e0270591
Hauptverfasser:	Rigter, Lisanne S, Snaebjornsson, Petur, Rosenberg, Efraim H, Altena, Estelle, van Grieken, Nicole C. T, Aleman, Berthe M. P, Kerst, Jan M, Morton, Lindsay, Schaapveld, Michael, Meijer, Gerrit A, van Leeuwen, Flora E, van Leerdam, Monique E
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma Biology and life sciences Cancer therapies Chromosomes Colorectal cancer Complications and side effects Diagnosis DNA methylation Epstein-Barr virus Esophagus Gastric cancer Genes Genomes Genomic instability Health risks Histopathology Hodgkin's disease Hodgkin's lymphoma Irradiation Lymphoma Medical diagnosis Medical research Medicine and Health Sciences Metastasis Microsatellite instability Mismatch repair MLH1 protein Mutation p53 Protein Pathogenesis Pathology Patients Population Radiation therapy Stability analysis Stomach cancer Testes Testicular cancer Tumors Viruses
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