Nucleosome assembly and disassembly pathways in vitro

Structural fluctuations of nucleosomes modulate the access to internal DNA in eukaryotic cells; clearly characterisation of this fundamental process is crucial to understanding gene regulation. Here we apply PhAST (Photochemical Analysis of Structural Transitions) to monitor at a base pair level, st...

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Veröffentlicht in:	PloS one 2022-07, Vol.17 (7), p.e0267382-e0267382
Hauptverfasser:	Hatakeyama, Akiko, Shymko, Yuliia, Hartmann, Brigitte, Retureau, Romain, Nogues, Claude, Pasi, Marco, Buckle, Malcolm
Format:	Artikel
Sprache:	eng
Schlagworte:	Amplitudes Analysis Asymmetry Binding Biochemistry, Molecular Biology Biology and life sciences Biophysics Chromatin Deoxyribonucleic acid Dismantling DNA Experiments Extremities Gene expression Gene regulation Gene sequencing Genetics Genomics Histones Human genetics Life Sciences Nucleosomes Nucleotide sequence Photochemicals Physical Sciences Proteins Research and Analysis Methods
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