Down-expression of klotho in canine mammary gland tumors and its prognostic significance

Since the discovery of klotho as an anti-aging gene, its association with tumors has been studied. Several previous studies have reported the down-expression of klotho in various human cancers, and much of its mechanism has been revealed. Nonetheless, the significance of klotho in canine mammary gla...

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Veröffentlicht in:	PloS one 2022-06, Vol.17 (6), p.e0265248-e0265248
Hauptverfasser:	Chung, Heaji, Lee, Sungin, Kim, Geon A, Kim, Wan Hee
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging Analysis Biology and Life Sciences Breast cancer Cancer therapies Colorectal cancer Diagnosis Dogs Gastric cancer Gene expression Genetic aspects Health aspects Immunohistochemistry Insulin-like growth factors Kidney cancer Kinases Klotho protein Laboratories Liver cancer Malignancy Mammary gland Mammary glands Medical prognosis Medicine and Health Sciences Metastases Metastasis Polyclonal antibodies Proteins Surgery Survival Tumors Veterinary medicine
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