Plasma antibodies from humans infected with zoonotic simian foamy virus do not inhibit cell-to-cell transmission of the virus despite binding to the surface of infected cells

Zoonotic simian foamy viruses (SFV) establish lifelong infection in their human hosts. Despite repeated transmission of SFV from nonhuman primates to humans, neither transmission between human hosts nor severe clinical manifestations have been reported. We aim to study the immune responses elicited...

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Veröffentlicht in:	PLoS pathogens 2022-05, Vol.18 (5), p.e1010470-e1010470
Hauptverfasser:	Couteaudier, Mathilde, Montange, Thomas, Njouom, Richard, Bilounga-Ndongo, Chanceline, Gessain, Antoine, Buseyne, Florence
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies Binding sites Biology and Life Sciences Blood plasma Cell migration Cell spreading Cell surface Chronic infection Cloning Cytometry Disease transmission DNA Viruses Env protein Ethics Fluorescence Fluorescence microscopy Gorilla gorilla Health aspects Heparan sulfate Hominidae Host-virus relationships Humans Immune response Infections Laboratories Life Sciences Localization Medicine and Health Sciences Mutation Observations Plasma Plasmids Proteins Research and Analysis Methods Retention Retroviridae Infections Retroviruses Simian foamy virus Spumavirus Staining Strains (organisms) Transmitters Viral envelope proteins Virulence (Microbiology) Virus research Viruses Zoonoses
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