Hepcidin is potential regulator for renin activity

An association between genetic variants in the genes HFE, HJV, BMP4 and arterial hypertension has been shown earlier. Proteins encoded by these genes participate in the signalling routes leading eventually to the production of the peptide hormone hepcidin. Mutations in these genes have been associat...

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Veröffentlicht in:	PloS one 2022-04, Vol.17 (4), p.e0267343-e0267343
Hauptverfasser:	Piesanen, Jaakko, Valjakka, Jarkko, Niemelä, Sanna, Borgenström, Marjut, Nikkari, Seppo, Hytönen, Vesa, Määttä, Juha, Kunnas, Tarja
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Angiotensin Angiotensinogen Angiotensinogen - genetics Atherosclerosis Binding Biology and Life Sciences Blood Pressure Conversion Enzymatic activity Enzyme activity Enzymes Genes Genetic diversity Genetic transcription Genetic variance Hepcidin Hepcidins - genetics Hepcidins - pharmacology Humans Hypertension Hypoxia Inhibitors Interferometry Iron Medicine Medicine and Health Sciences Modelling Molecular modelling Mutation Peptides Proteins Renin Renin-Angiotensin System Research and Analysis Methods
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