Phage-inducible chromosomal islands promote genetic variability by blocking phage reproduction and protecting transductants from phage lysis

Phage-inducible chromosomal islands (PICIs) are a widespread family of highly mobile genetic elements that disseminate virulence and toxin genes among bacterial populations. Since their life cycle involves induction by helper phages, they are important players in phage evolution and ecology. PICIs c...

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Veröffentlicht in:	PLoS genetics 2022-03, Vol.18 (3), p.e1010146
Hauptverfasser:	Ibarra-Chávez, Rodrigo, Brady, Aisling, Chen, John, Penadés, José R, Haag, Andreas F
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibiotic resistance Bacteria Bacteria - genetics Bacteriophages Bacteriophages - genetics Biology and Life Sciences Cell death Cell viability Chromosomes Cloning CRISPR Defense mechanisms Deoxyribonucleic acid DNA Earth Sciences Ecology and Environmental Sciences Evolution Gene transfer Gene Transfer, Horizontal - genetics Genes Genetic aspects Genetic variability Genetic variation Genomic Islands - genetics Heredity Horizontal transfer Infections Islands Life cycles Lysis Lysogenization Packaging machinery Phages Physiological aspects Population Population genetics Reproduction Virulence
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