Identification of host transcriptome-guided repurposable drugs for SARS-CoV-1 infections and their validation with SARS-CoV-2 infections by using the integrated bioinformatics approaches

Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) is one of the most severe global pandemic due to its high pathogenicity and death rate starting from the end of 2019. Though there are some vaccines available against SAER-CoV-2 infections, we are worried about their effectiveness, due to...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	PloS one 2022-04, Vol.17 (4), p.e0266124-e0266124
Hauptverfasser:	Ahmed, Fee Faysal, Reza, Md Selim, Sarker, Md Shahin, Islam, Md Samiul, Mosharaf, Md Parvez, Hasan, Sohel, Mollah, Md Nurul Haque
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Angiogenesis Antiviral agents Antiviral Agents - pharmacology Apoptosis Arsenic Arsenic trioxide Binding Bioinformatics Biological activity Biology and life sciences Biomarkers Cancer Cell death Chemokines Computational Biology Coronaviruses COVID-19 - drug therapy COVID-19 vaccines Cyclosporins Cytokines Disease Drug development Drug Repositioning Drugs Ets-1 protein Gene expression Gene regulation Genes Genetic transcription Health risks Health services Humans Hypoxia Immune response Immunosuppressive agents Infections Ivermectin Literature reviews Lung diseases Medicine and health sciences MicroRNAs - genetics Molecular docking Molecular Docking Simulation Mortality Network analysis Oxidative stress Oxidoreductase Pandemics Pathogenicity Pathogens Pathways Physical Sciences Protein-protein interactions Proteins Rapamycin Receptors Regulation Respiratory diseases SARS Virus SARS-CoV-2 - genetics Severe acute respiratory syndrome Severe Acute Respiratory Syndrome - drug therapy Severe acute respiratory syndrome coronavirus 2 Signal transduction Sulfates Tacrolimus Therapeutic targets Transcription factors Transcription Factors - genetics Transcriptome Vaccines Viral diseases Viruses
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!