Plasma DNA and deoxyribonuclease are associated with glucose metabolism in healthy mice

It is currently unknown why obesity leads in some patients to prediabetes and metabolic syndrome. Microinflammation potentially caused by extracellular DNA is supposed to be involved. The aim of this cross-sectional study in healthy mice was to analyze the association between plasma extracellular DN...

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Veröffentlicht in:	PloS one 2022-04, Vol.17 (4), p.e0265099-e0265099
Hauptverfasser:	Kmeťová, Katarína, Čonka, Jozef, Janko, Jakub, Illés, Júlia, Uličná, Oľga, Celec, Peter
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Animals Biology and life sciences Blood glucose Blood Glucose - metabolism Cholesterol Cross-Sectional Studies Deoxyribonuclease Deoxyribonucleases - blood Deoxyribonucleic acid Diffusion rate DNA DNA - blood Fasting Female Genetic aspects Glucose Glucose metabolism Glucose tolerance Insulin Insulin - metabolism Insulin resistance Insulin Resistance - physiology Laboratory testing Liver Medical screening Medicine Medicine and Health Sciences Metabolic disorders Metabolic Syndrome Mice Mitochondrial DNA Obesity Physical Sciences Physiological aspects Plasma Prediabetic State Research and Analysis Methods Sensitivity Statistical analysis Therapeutic targets Weight control
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