SARS-CoV-2 detection in multi-sample pools in a real pandemic scenario: A screening strategy of choice for active surveillance

The current COVID-19 pandemic has overloaded the diagnostic capacity of laboratories by the gold standard method rRT-PCR. This disease has a high spread rate and almost a quarter of infected individuals never develop symptoms. In this scenario, active surveillance is crucial to stop the virus propag...

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Veröffentlicht in:	PloS one 2022-04, Vol.17 (4), p.e0266408-e0266408
Hauptverfasser:	Castellaro, Andrés Marcos, Velez, Pablo, Giaj Merlera, Guillermo, Rondan Dueñas, Juan, Condat, Felix, Gallardo, Jesica, Makhoul, Aylen, Cinalli, Camila, Rosales Cavaglieri, Lorenzo, Di Cola, Guadalupe, Sicilia, Paola, López, Laura, Bocco, José Luis, Barbás, María Gabriela, Cardozo, Diego Hernán, Pisano, María Belén, Ré, Viviana, Belaus, Andrea, Castro, Gonzalo
Format:	Artikel
Sprache:	eng
Schlagworte:	Argentina Biology and Life Sciences Comparative analysis Control Coronaviruses COVID-19 COVID-19 - diagnosis COVID-19 - epidemiology Cycle protein Diagnostic systems Dilution Disease Engineering and Technology Epidemics Feasibility studies Health surveillance Humans Medicine and Health Sciences Methods N gene Nucleic acids Overloading Pandemics Pools RNA, Viral - genetics SARS-CoV-2 - genetics Sensitivity and Specificity Sentinel health events Severe acute respiratory syndrome Severe acute respiratory syndrome coronavirus 2 Signs and symptoms Specimen Handling - methods Supervision Surveillance Viral diseases Viruses Watchful Waiting
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