Keap1 recognizes EIAV early accessory protein Rev to promote antiviral defense

The Nrf2/Keap1 axis plays a complex role in viral susceptibility, virus-associated inflammation and immune regulation in host cells. However, whether or how the Nrf2/Keap1 axis is involved in the interactions between equine lentiviruses and their hosts remains unclear. Here, we demonstrate that the...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	PLoS pathogens 2022-02, Vol.18 (2), p.e1009986-e1009986
Hauptverfasser:	Wang, Yan, Ma, Guanqin, Wang, Xue-Feng, Na, Lei, Guo, Xing, Zhang, Jiaqi, Liu, Cong, Du, Cheng, Qi, Ting, Lin, Yuezhi, Wang, Xiaojun
Format:	Artikel
Sprache:	eng
Schlagworte:	Antioxidants Antioxidants - metabolism Antiviral Agents - pharmacology Antiviral drugs Biology and Life Sciences Cell Nucleus - drug effects Cell Nucleus - metabolism Cloning Control Cytoplasm Defensive behavior Development and progression Diagnosis Equine infectious anemia Gene expression Gene Products, rev - metabolism Genetic aspects Growth Health aspects Homeostasis Humans Immunoregulation Infections Infectious Anemia Virus, Equine - metabolism Kelch-Like ECH-Associated Protein 1 - metabolism Lentivirus Medicine and Health Sciences Molecular modelling NF-E2-Related Factor 2 - metabolism Oxidative stress Oxidative Stress - drug effects Pathogenesis Phosphorylation Proteins Research and analysis methods Risk factors RNA transport Signal Transduction - drug effects Transcription Viral infections Viral proteins Viruses
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!