MAPK-mediated transcription factor GATAd contributes to Cry1Ac resistance in diamondback moth by reducing PxmALP expression

The benefits of biopesticides and transgenic crops based on the insecticidal Cry-toxins from Bacillus thuringiensis (Bt) are considerably threatened by insect resistance evolution, thus, deciphering the molecular mechanisms underlying insect resistance to Bt products is of great significance to thei...

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Veröffentlicht in:	PLoS genetics 2022-02, Vol.18 (2), p.e1010037-e1010037
Hauptverfasser:	Guo, Le, Cheng, Zhouqiang, Qin, Jianying, Sun, Dan, Wang, Shaoli, Wu, Qingjun, Crickmore, Neil, Zhou, Xuguo, Bravo, Alejandra, Soberón, Mario, Guo, Zhaojiang, Zhang, Youjun
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptation Agricultural pests Agricultural production Agricultural research Animals Bacillus thuringiensis - genetics Bacillus thuringiensis - metabolism Bacillus thuringiensis Toxins - metabolism Bacillus thuringiensis Toxins - pharmacology Bacterial Proteins - genetics Binding sites Biology and Life Sciences Cellular signal transduction Cloning Cry1Ac toxin Endotoxins - metabolism Endotoxins - pharmacology Gene expression Gene silencing Genetic aspects Granulovirus - genetics Hemolysin Proteins - metabolism Hemolysin Proteins - pharmacology Insect Proteins - genetics Insecticide Resistance - genetics Insecticides - metabolism Insects Larva - genetics MAP kinase MAP Kinase Signaling System - drug effects MAP Kinase Signaling System - physiology Medicine and Health Sciences Mitogen-activated protein kinases Molecular modelling Moths - genetics Moths - metabolism Mutation Pest resistance Pesticide resistance Phenotypes Physiological aspects Plasmids Proteins Signal transduction Toxins Transcription factors Transcription Factors - genetics
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