Superiority of tenofovir alafenamide fumarate over entecavir for serum HBsAg level reduction in patients with chronic HBV infection: A 144-week outcome study after switching of the nucleos(t)ide analog

To evaluate the long-term efficacy of switching of the nucleos(t)ide analog used for treatment from entecavir (ETV) to tenofovir alafenamide fumarate (TAF) in patients with chronic HBV infection. A total of 103 patients with serum HBsAg levels of ≥100 IU/mL who had received ETV were enrolled. The nu...

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Veröffentlicht in:	PloS one 2022-02, Vol.17 (2), p.e0262764-e0262764
Hauptverfasser:	Uchida, Yoshihito, Nakao, Masamitsu, Yamada, Shunsuke, Tsuji, Shohei, Uemura, Hayato, Kouyama, Jun-Ichi, Naiki, Kayoko, Sugawara, Kayoko, Nakayama, Nobuaki, Imai, Yukinori, Tomiya, Tomoaki, Mochida, Satoshi
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Alanine - therapeutic use Antiretroviral drugs Antiviral Agents - therapeutic use Antiviral drugs Architects Biology and Life Sciences Chronic infection Creatinine Drug Substitution - methods Enzymes Female Follow-Up Studies Fumarates - therapeutic use Gastroenterology Genotype Genotypes Guanine - analogs & derivatives Guanine - therapeutic use Hepatitis B Hepatitis B surface antigen Hepatitis B Surface Antigens - blood Hepatitis B virus - genetics Hepatitis B virus - immunology Hepatitis B, Chronic - blood Hepatitis B, Chronic - drug therapy Hepatitis B, Chronic - virology Hepatitis C Hepatology Humans Immunoassay Infections Laboratories Male Medicine Medicine and Health Sciences Middle Aged Nucleosides - therapeutic use Patients Prospective Studies Reduction Switching Tenofovir Tenofovir - analogs & derivatives Tenofovir - therapeutic use Treatment Outcome
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