Limitations of bacterial culture, viral PCR, and tulathromycin susceptibility from upper respiratory tract samples in predicting clinical outcome of tulathromycin control or treatment of bovine respiratory disease in high-risk feeder heifers

A cross-sectional prospective cohort study including 1026 heifers administered tulathromycin due to high risk of clinical signs of bovine respiratory disease (BRD), measured poor association between BRD clinical outcomes and results of bacterial culture and tulathromycin susceptibility from BRD isol...

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Veröffentlicht in:	PloS one 2022-02, Vol.17 (2), p.e0247213-e0247213
Hauptverfasser:	Sarchet, Jeffrey J, Pollreisz, John P, Bechtol, David T, Blanding, Mitchell R, Saltman, Roger L, Taube, Patrick C
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Animals Anti-Bacterial Agents - pharmacology Anti-Bacterial Agents - therapeutic use Antimicrobial agents Bacterial infections Biology and Life Sciences Bovine respiratory disease complex Bovine Respiratory Disease Complex - drug therapy Bovine Respiratory Disease Complex - microbiology Bovine Respiratory Disease Complex - pathology Care and treatment Cattle Cattle Diseases - drug therapy Cattle Diseases - microbiology Cattle Diseases - pathology Clinical outcomes Confidence intervals Cross-Sectional Studies Diarrhea Diarrhea Viruses, Bovine Viral - drug effects Diarrhea Viruses, Bovine Viral - genetics Diarrhea Viruses, Bovine Viral - isolation & purification Disaccharides - pharmacology Disaccharides - therapeutic use DNA, Viral - genetics DNA, Viral - metabolism Drug dosages Health risks Health services Herpesvirus 1, Bovine - drug effects Herpesvirus 1, Bovine - genetics Herpesvirus 1, Bovine - isolation & purification Heterocyclic Compounds - pharmacology Heterocyclic Compounds - therapeutic use Infections Mannheimia haemolytica - drug effects Mannheimia haemolytica - isolation & purification Medicine and Health Sciences Microbial Sensitivity Tests Nasopharynx - microbiology Nasopharynx - virology Nucleic acids Parainfluenza Pasteurella multocida - drug effects Pasteurella multocida - isolation & purification Pathogens Polymerase Chain Reaction Prospective Studies Respiratory diseases Respiratory syncytial virus Respiratory Syncytial Virus, Bovine - drug effects Respiratory Syncytial Virus, Bovine - genetics Respiratory Syncytial Virus, Bovine - isolation & purification Respiratory tract Risk Risk Factors RNA, Viral - genetics RNA, Viral - metabolism Treatment Failure Veterinary medicine Viruses
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