Health-related quality of life of younger and older lower-income households in Malaysia
Globally, a lower income is associated with poorer health status and reduced quality of life (QOL). However, more research is needed on how being older may influence QOL in lower-income households, particularly as older age is associated with an increased risk of chronic diseases and care needs. To...
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description | Globally, a lower income is associated with poorer health status and reduced quality of life (QOL). However, more research is needed on how being older may influence QOL in lower-income households, particularly as older age is associated with an increased risk of chronic diseases and care needs. To this end, the current study attempts to determine the health-related QOL (HRQOL) among individuals from lower-income households aged 60 years and over compared to lower-income adults aged less than 60 years.
Participants were identified from the Department of Statistics Malaysia sampling frame. Surveys were carried out with individual households aged 18 years and older through self-administered questionnaires. Information was collected on demographics, household income, employment status, number of diseases, and HRQOL assessed using the EuroQol 5-Dimension 5-Level (EQ-5D-5L) tool.
Out of a total of 1899 participants, 620 (32.6%) were female and 328 (17.3%) were aged 60 years and above. The mean (SD) age was 45.2 (14.1) and mean (SD) household income was RM2124 (1356). Compared with younger individuals, older respondents were more likely to experience difficulties in mobility (32.1% vs 9.7%, p |
doi_str_mv | 10.1371/journal.pone.0263751 |
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Participants were identified from the Department of Statistics Malaysia sampling frame. Surveys were carried out with individual households aged 18 years and older through self-administered questionnaires. Information was collected on demographics, household income, employment status, number of diseases, and HRQOL assessed using the EuroQol 5-Dimension 5-Level (EQ-5D-5L) tool.
Out of a total of 1899 participants, 620 (32.6%) were female and 328 (17.3%) were aged 60 years and above. The mean (SD) age was 45.2 (14.1) and mean (SD) household income was RM2124 (1356). Compared with younger individuals, older respondents were more likely to experience difficulties in mobility (32.1% vs 9.7%, p<0.001), self-care (11.6% vs 3.8%, p<0.001), usual activities (24.5% vs 9.1%, p<0.001), pain/discomfort (38.8% vs 16.5%, p<0.001) and anxiety/depression (21.4% vs 13.5%, p<0.001). The mean (SD) EQ-5D index scores were lower among older respondents, 0.89 (0.16) vs 0.95 (0.13), p = 0.001. After adjusting for covariates, age was a significant influencing factor (p = 0.001) for mobility (OR = 2.038, 95% CI:1.439-2.885), usual activities (OR = 1.957, 95% CI:1.353-2.832) and pain or discomfort (OR = 2.241, 95% CI:1.690-2.972).
Lower-income older adults had poorer HRQOL compared to their younger counterparts. This has important implications concerning intervention strategies that incorporate active ageing concepts on an individual and policy-making level to enhance the QOL and wellbeing, particularly among the older lower-income population.</description><identifier>ISSN: 1932-6203</identifier><identifier>EISSN: 1932-6203</identifier><identifier>DOI: 10.1371/journal.pone.0263751</identifier><identifier>PMID: 35134086</identifier><language>eng</language><publisher>United States: Public Library of Science</publisher><subject>Adult ; Adults ; Age ; Age Factors ; Aged ; Aged, 80 and over ; Aging ; Biology and Life Sciences ; Chronic illnesses ; COVID-19 ; Cross-Sectional Studies ; Demographic aspects ; Demographics ; Demography ; Developing Countries - economics ; Discomfort ; Economic aspects ; Female ; Health aspects ; Health risks ; Health Status ; Households ; Humans ; Income ; Malaysia - ethnology ; Male ; Medicine and Health Sciences ; Middle Aged ; Mobility ; Older people ; Pain ; People and Places ; Personal income ; Preventive medicine ; Quality of life ; Quality of Life - psychology ; Self Care ; Self-care, Health ; Social Sciences ; Sociodemographic Factors ; Socioeconomic Factors ; Surveys and Questionnaires</subject><ispartof>PloS one, 2022-02, Vol.17 (2), p.e0263751-e0263751</ispartof><rights>COPYRIGHT 2022 Public Library of Science</rights><rights>2022 Rizal et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>2022 Rizal et al 2022 Rizal et al</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c6071-fd53ca3d118a67b83a4dcad35044bba6f016a758ced7fd7fa63315e2fe15ae963</citedby><cites>FETCH-LOGICAL-c6071-fd53ca3d118a67b83a4dcad35044bba6f016a758ced7fd7fa63315e2fe15ae963</cites><orcidid>0000-0003-0387-6406 ; 0000-0001-9229-1586 ; 0000-0002-3400-8540</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC8824345/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC8824345/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,864,885,2102,2928,23866,27924,27925,53791,53793,79600,79601</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/35134086$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><contributor>Boon-Peng, Hoh</contributor><creatorcontrib>Rizal, Hussein</creatorcontrib><creatorcontrib>Said, Mas Ayu</creatorcontrib><creatorcontrib>Abdul Majid, Hazreen</creatorcontrib><creatorcontrib>Su, Tin Tin</creatorcontrib><creatorcontrib>Maw Pin, Tan</creatorcontrib><creatorcontrib>Ismail, Rozmi</creatorcontrib><creatorcontrib>Shah Zaidi, Mohd Azlan</creatorcontrib><title>Health-related quality of life of younger and older lower-income households in Malaysia</title><title>PloS one</title><addtitle>PLoS One</addtitle><description>Globally, a lower income is associated with poorer health status and reduced quality of life (QOL). However, more research is needed on how being older may influence QOL in lower-income households, particularly as older age is associated with an increased risk of chronic diseases and care needs. To this end, the current study attempts to determine the health-related QOL (HRQOL) among individuals from lower-income households aged 60 years and over compared to lower-income adults aged less than 60 years.
Participants were identified from the Department of Statistics Malaysia sampling frame. Surveys were carried out with individual households aged 18 years and older through self-administered questionnaires. Information was collected on demographics, household income, employment status, number of diseases, and HRQOL assessed using the EuroQol 5-Dimension 5-Level (EQ-5D-5L) tool.
Out of a total of 1899 participants, 620 (32.6%) were female and 328 (17.3%) were aged 60 years and above. The mean (SD) age was 45.2 (14.1) and mean (SD) household income was RM2124 (1356). Compared with younger individuals, older respondents were more likely to experience difficulties in mobility (32.1% vs 9.7%, p<0.001), self-care (11.6% vs 3.8%, p<0.001), usual activities (24.5% vs 9.1%, p<0.001), pain/discomfort (38.8% vs 16.5%, p<0.001) and anxiety/depression (21.4% vs 13.5%, p<0.001). The mean (SD) EQ-5D index scores were lower among older respondents, 0.89 (0.16) vs 0.95 (0.13), p = 0.001. After adjusting for covariates, age was a significant influencing factor (p = 0.001) for mobility (OR = 2.038, 95% CI:1.439-2.885), usual activities (OR = 1.957, 95% CI:1.353-2.832) and pain or discomfort (OR = 2.241, 95% CI:1.690-2.972).
Lower-income older adults had poorer HRQOL compared to their younger counterparts. This has important implications concerning intervention strategies that incorporate active ageing concepts on an individual and policy-making level to enhance the QOL and wellbeing, particularly among the older lower-income population.</description><subject>Adult</subject><subject>Adults</subject><subject>Age</subject><subject>Age Factors</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Aging</subject><subject>Biology and Life Sciences</subject><subject>Chronic illnesses</subject><subject>COVID-19</subject><subject>Cross-Sectional Studies</subject><subject>Demographic aspects</subject><subject>Demographics</subject><subject>Demography</subject><subject>Developing Countries - economics</subject><subject>Discomfort</subject><subject>Economic aspects</subject><subject>Female</subject><subject>Health aspects</subject><subject>Health risks</subject><subject>Health Status</subject><subject>Households</subject><subject>Humans</subject><subject>Income</subject><subject>Malaysia - ethnology</subject><subject>Male</subject><subject>Medicine and Health Sciences</subject><subject>Middle Aged</subject><subject>Mobility</subject><subject>Older people</subject><subject>Pain</subject><subject>People and Places</subject><subject>Personal income</subject><subject>Preventive medicine</subject><subject>Quality of life</subject><subject>Quality of Life - psychology</subject><subject>Self Care</subject><subject>Self-care, Health</subject><subject>Social Sciences</subject><subject>Sociodemographic Factors</subject><subject>Socioeconomic Factors</subject><subject>Surveys and Questionnaires</subject><issn>1932-6203</issn><issn>1932-6203</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>DOA</sourceid><recordid>eNqNkl2L1DAUhoso7jr6D0QLguhFx6Rp0_ZGWBZ1B1YW_LwMp8lpJ0OmmU1adf696U53mcpeSAI5JM95k3PyRtFzSpaUFfTdxg6uA7Pc2Q6XJOWsyOmD6JRWLE14StjDo_gkeuL9hpCclZw_jk5YTllGSn4a_bxAMP06cWigRxVfD2B0v49tExvd4Lju7dC16GLoVGyNCpGxv9ElupN2i_HaDh7X4cDHuos_g4G91_A0etSA8fhsWhfR948fvp1fJJdXn1bnZ5eJ5KSgSaNyJoEpSkvgRV0yyJQExXKSZXUNvCGUQ5GXElXRhAmcMZpj2iDNASvOFtHLg-7OWC-mnniR8pSXZZmH2hfR6kAoCxuxc3oLbi8saHGzYV0rwPVaGhQ8zZgCJFnFZMZqVVcVryugFKFOU54FrffTbUO9RSWx6x2Ymej8pNNr0dpfoiyDdJYHgTeTgLPXA_pebLWXaAx0GPo4vrsYv6YYK3v1D3p_dRPVQihAd40N98pRVJzxKs1JSoqRWt5DhaFwq2UwUKPD_izh7SwhMD3-6VsYvBerr1_-n736MWdfH7HrG-95a4Ze287PwewASme9d9jcNZkSMfr_thti9L-Y_B_SXhx_0F3SreHZX3ut_-I</recordid><startdate>20220208</startdate><enddate>20220208</enddate><creator>Rizal, Hussein</creator><creator>Said, Mas Ayu</creator><creator>Abdul Majid, Hazreen</creator><creator>Su, Tin Tin</creator><creator>Maw Pin, Tan</creator><creator>Ismail, Rozmi</creator><creator>Shah Zaidi, Mohd Azlan</creator><general>Public Library of Science</general><general>Public Library of Science (PLoS)</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>IOV</scope><scope>ISR</scope><scope>3V.</scope><scope>7QG</scope><scope>7QL</scope><scope>7QO</scope><scope>7RV</scope><scope>7SN</scope><scope>7SS</scope><scope>7T5</scope><scope>7TG</scope><scope>7TM</scope><scope>7U9</scope><scope>7X2</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FD</scope><scope>8FE</scope><scope>8FG</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABJCF</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>ARAPS</scope><scope>ATCPS</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>COVID</scope><scope>D1I</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB.</scope><scope>KB0</scope><scope>KL.</scope><scope>L6V</scope><scope>LK8</scope><scope>M0K</scope><scope>M0S</scope><scope>M1P</scope><scope>M7N</scope><scope>M7P</scope><scope>M7S</scope><scope>NAPCQ</scope><scope>P5Z</scope><scope>P62</scope><scope>P64</scope><scope>PATMY</scope><scope>PDBOC</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PTHSS</scope><scope>PYCSY</scope><scope>RC3</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope><orcidid>https://orcid.org/0000-0003-0387-6406</orcidid><orcidid>https://orcid.org/0000-0001-9229-1586</orcidid><orcidid>https://orcid.org/0000-0002-3400-8540</orcidid></search><sort><creationdate>20220208</creationdate><title>Health-related quality of life of younger and older lower-income households in Malaysia</title><author>Rizal, Hussein ; Said, Mas Ayu ; Abdul Majid, Hazreen ; Su, Tin Tin ; Maw Pin, Tan ; Ismail, Rozmi ; Shah Zaidi, Mohd Azlan</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c6071-fd53ca3d118a67b83a4dcad35044bba6f016a758ced7fd7fa63315e2fe15ae963</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Adult</topic><topic>Adults</topic><topic>Age</topic><topic>Age Factors</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Aging</topic><topic>Biology and Life Sciences</topic><topic>Chronic illnesses</topic><topic>COVID-19</topic><topic>Cross-Sectional Studies</topic><topic>Demographic aspects</topic><topic>Demographics</topic><topic>Demography</topic><topic>Developing Countries - economics</topic><topic>Discomfort</topic><topic>Economic aspects</topic><topic>Female</topic><topic>Health aspects</topic><topic>Health risks</topic><topic>Health Status</topic><topic>Households</topic><topic>Humans</topic><topic>Income</topic><topic>Malaysia - ethnology</topic><topic>Male</topic><topic>Medicine and Health Sciences</topic><topic>Middle Aged</topic><topic>Mobility</topic><topic>Older people</topic><topic>Pain</topic><topic>People and Places</topic><topic>Personal income</topic><topic>Preventive medicine</topic><topic>Quality of life</topic><topic>Quality of Life - psychology</topic><topic>Self Care</topic><topic>Self-care, Health</topic><topic>Social Sciences</topic><topic>Sociodemographic Factors</topic><topic>Socioeconomic Factors</topic><topic>Surveys and Questionnaires</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Rizal, Hussein</creatorcontrib><creatorcontrib>Said, Mas Ayu</creatorcontrib><creatorcontrib>Abdul Majid, Hazreen</creatorcontrib><creatorcontrib>Su, Tin Tin</creatorcontrib><creatorcontrib>Maw Pin, Tan</creatorcontrib><creatorcontrib>Ismail, Rozmi</creatorcontrib><creatorcontrib>Shah Zaidi, Mohd Azlan</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Gale In Context: Opposing Viewpoints</collection><collection>Gale In Context: Science</collection><collection>ProQuest Central (Corporate)</collection><collection>Animal Behavior Abstracts</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Biotechnology Research Abstracts</collection><collection>Nursing & Allied Health Database</collection><collection>Ecology Abstracts</collection><collection>Entomology Abstracts (Full archive)</collection><collection>Immunology Abstracts</collection><collection>Meteorological & Geoastrophysical Abstracts</collection><collection>Nucleic Acids Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Agricultural Science Collection</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Technology Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Materials Science & Engineering Collection</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>Advanced Technologies & Aerospace Collection</collection><collection>Agricultural & Environmental Science Collection</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Technology Collection</collection><collection>Natural Science Collection</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>Coronavirus Research Database</collection><collection>ProQuest Materials Science Collection</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Materials Science Database</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Meteorological & Geoastrophysical Abstracts - 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Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>DOAJ Directory of Open Access Journals</collection><jtitle>PloS one</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Rizal, Hussein</au><au>Said, Mas Ayu</au><au>Abdul Majid, Hazreen</au><au>Su, Tin Tin</au><au>Maw Pin, Tan</au><au>Ismail, Rozmi</au><au>Shah Zaidi, Mohd Azlan</au><au>Boon-Peng, Hoh</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Health-related quality of life of younger and older lower-income households in Malaysia</atitle><jtitle>PloS one</jtitle><addtitle>PLoS One</addtitle><date>2022-02-08</date><risdate>2022</risdate><volume>17</volume><issue>2</issue><spage>e0263751</spage><epage>e0263751</epage><pages>e0263751-e0263751</pages><issn>1932-6203</issn><eissn>1932-6203</eissn><abstract>Globally, a lower income is associated with poorer health status and reduced quality of life (QOL). However, more research is needed on how being older may influence QOL in lower-income households, particularly as older age is associated with an increased risk of chronic diseases and care needs. To this end, the current study attempts to determine the health-related QOL (HRQOL) among individuals from lower-income households aged 60 years and over compared to lower-income adults aged less than 60 years.
Participants were identified from the Department of Statistics Malaysia sampling frame. Surveys were carried out with individual households aged 18 years and older through self-administered questionnaires. Information was collected on demographics, household income, employment status, number of diseases, and HRQOL assessed using the EuroQol 5-Dimension 5-Level (EQ-5D-5L) tool.
Out of a total of 1899 participants, 620 (32.6%) were female and 328 (17.3%) were aged 60 years and above. The mean (SD) age was 45.2 (14.1) and mean (SD) household income was RM2124 (1356). Compared with younger individuals, older respondents were more likely to experience difficulties in mobility (32.1% vs 9.7%, p<0.001), self-care (11.6% vs 3.8%, p<0.001), usual activities (24.5% vs 9.1%, p<0.001), pain/discomfort (38.8% vs 16.5%, p<0.001) and anxiety/depression (21.4% vs 13.5%, p<0.001). The mean (SD) EQ-5D index scores were lower among older respondents, 0.89 (0.16) vs 0.95 (0.13), p = 0.001. After adjusting for covariates, age was a significant influencing factor (p = 0.001) for mobility (OR = 2.038, 95% CI:1.439-2.885), usual activities (OR = 1.957, 95% CI:1.353-2.832) and pain or discomfort (OR = 2.241, 95% CI:1.690-2.972).
Lower-income older adults had poorer HRQOL compared to their younger counterparts. This has important implications concerning intervention strategies that incorporate active ageing concepts on an individual and policy-making level to enhance the QOL and wellbeing, particularly among the older lower-income population.</abstract><cop>United States</cop><pub>Public Library of Science</pub><pmid>35134086</pmid><doi>10.1371/journal.pone.0263751</doi><tpages>e0263751</tpages><orcidid>https://orcid.org/0000-0003-0387-6406</orcidid><orcidid>https://orcid.org/0000-0001-9229-1586</orcidid><orcidid>https://orcid.org/0000-0002-3400-8540</orcidid><oa>free_for_read</oa></addata></record> |
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recordid | cdi_plos_journals_2626888520 |
source | MEDLINE; DOAJ Directory of Open Access Journals; Public Library of Science (PLoS) Journals Open Access; EZB-FREE-00999 freely available EZB journals; PubMed Central; Free Full-Text Journals in Chemistry |
subjects | Adult Adults Age Age Factors Aged Aged, 80 and over Aging Biology and Life Sciences Chronic illnesses COVID-19 Cross-Sectional Studies Demographic aspects Demographics Demography Developing Countries - economics Discomfort Economic aspects Female Health aspects Health risks Health Status Households Humans Income Malaysia - ethnology Male Medicine and Health Sciences Middle Aged Mobility Older people Pain People and Places Personal income Preventive medicine Quality of life Quality of Life - psychology Self Care Self-care, Health Social Sciences Sociodemographic Factors Socioeconomic Factors Surveys and Questionnaires |
title | Health-related quality of life of younger and older lower-income households in Malaysia |
url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-26T05%3A29%3A08IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_plos_&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Health-related%20quality%20of%20life%20of%20younger%20and%20older%20lower-income%20households%20in%20Malaysia&rft.jtitle=PloS%20one&rft.au=Rizal,%20Hussein&rft.date=2022-02-08&rft.volume=17&rft.issue=2&rft.spage=e0263751&rft.epage=e0263751&rft.pages=e0263751-e0263751&rft.issn=1932-6203&rft.eissn=1932-6203&rft_id=info:doi/10.1371/journal.pone.0263751&rft_dat=%3Cgale_plos_%3EA692502070%3C/gale_plos_%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2626888520&rft_id=info:pmid/35134086&rft_galeid=A692502070&rft_doaj_id=oai_doaj_org_article_6243dae0493c43bdb996b9a11eab2264&rfr_iscdi=true |