Ceiling effect of clomiphene citrate on the testosterone to estradiol ratio in eugonadal infertile men

The testosterone to estradiol ratio (T/E2 ratio) reportedly exerts a stronger effect on semen quality and sexual desire than does testosterone alone. Clomiphene citrate is a selective estrogen receptor modulator that has long been used as an empirical treatment option in the management of idiopathic...

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Veröffentlicht in:	PloS one 2022-01, Vol.17 (1), p.e0262924-e0262924
Hauptverfasser:	Liao, Yian, Chang, Yi-Kai, Wang, Shuo-Meng, Chang, Hong-Chiang
Format:	Artikel
Sprache:	eng
Schlagworte:	17β-Estradiol Adult Biology and Life Sciences Citric acid Clomiphene Clomiphene - administration & dosage Dosage and administration Drug dosages Drug therapy Empirical analysis Estradiol Estradiol - blood Estrogen receptors Estrogens Health aspects Humans Hypogonadism - blood Hypogonadism - drug therapy Hypothalamus Immunoassay Infertility Infertility, Male Infertility, Male - blood Infertility, Male - drug therapy Luteinizing hormone Male Measurement Medicine and Health Sciences Middle Aged Oligozoospermia Patient outcomes Patients Physiological aspects Pituitary Pituitary gland Prolactin Retrospective Studies Semen Sex hormones Sperm Subgroups Testosterone Testosterone - blood Urology
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