Effect of enterally administered sleep-promoting medication on the intravenous sedative dose and its safety and cost profile in mechanically ventilated patients: A retrospective cohort study

The clinical effect of enteral administration of sleep-promoting medication (SPM) in mechanically ventilated patients remains unclear. This study aimed to investigate the relationship between enteral SPM administration and the intravenous sedative dose and examine the safety and cost of enteral SPM...

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Veröffentlicht in:	PloS one 2021-12, Vol.16 (12), p.e0261305-e0261305
Hauptverfasser:	Tsunemitsu, Takefumi, Kataoka, Yuki, Matsumoto, Masaru, Hashimoto, Takashi, Suzuki, Takao
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Intravenous Adverse events Aged Analgesics Anesthesia Benzodiazepines Biology and Life Sciences Body weight Central Nervous System Depressants - administration & dosage Cohort analysis Comorbidity Complications and side effects Confidence intervals Critical care Delirium Dosage Drug dosages Efficiency Enteral Nutrition - methods Female Fentanyl Health aspects Health risks Humans Hypnotics Hypnotics and Sedatives - administration & dosage Hypotension Indenes - administration & dosage Intensive care Intensive Care Units - statistics & numerical data Intravenous administration Length of Stay Male Mechanical ventilation Medical records Medicine and Health Sciences Melatonin Melatonin - administration & dosage Middle Aged Ostomy Patient outcomes Patients Propofol Propofol - administration & dosage Psychotropic drugs Regression analysis Regression models Research and Analysis Methods Respiration, Artificial - methods Retrospective Studies Safety Sedatives Sleep Sleep - drug effects Statistical analysis Tertiary Ventilation Ventilators
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