Evaluation of multi-assay algorithms for identifying individuals with recent HIV infection: HPTN 071 (PopART)

Assays and multi-assay algorithms (MAAs) have been developed for population-level cross-sectional HIV incidence estimation. These algorithms use a combination of serologic and/or non-serologic biomarkers to assess the duration of infection. We evaluated the performance of four MAAs for individual-le...

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Veröffentlicht in:	PloS one 2021-12, Vol.16 (12), p.e0258644-e0258644
Hauptverfasser:	Grant-McAuley, Wendy, Klock, Ethan, Laeyendecker, Oliver, Piwowar-Manning, Estelle, Wilson, Ethan, Clarke, William, Breaud, Autumn, Moore, Ayana, Ayles, Helen, Kosloff, Barry, Shanaube, Kwame, Bock, Peter, Mandla, Nomtha, van Deventer, Anneen, Fidler, Sarah, Donnell, Deborah, Hayes, Richard, Eshleman, Susan H
Format:	Artikel
Sprache:	eng
Schlagworte:	Acquired immune deficiency syndrome Adult AIDS Algorithms Analysis Anti-HIV Agents - therapeutic use Antiretroviral agents Antiretroviral drugs Antiretroviral therapy Antiretroviral Therapy, Highly Active Antiviral agents Assaying Assessments Avidity Biology and Life Sciences Biomarkers Complications and side effects Cross-Sectional Studies Diagnosis Disease prevention Female HIV HIV infection HIV Infections - diagnosis HIV Infections - drug therapy HIV Infections - epidemiology HIV Infections - virology HIV-1 - immunology Human immunodeficiency virus Humans Immunoenzyme Techniques Incidence Infections Infectious diseases Male Medicine and Health Sciences Middle Aged Patient outcomes Performance evaluation Physical Sciences Research and Analysis Methods Sensitivity analysis Sensitivity and Specificity Seroconversion South Africa - epidemiology Time Factors Tutu, Desmond Viral Load - drug effects Zambia - epidemiology
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