Co-option of immune effectors by the hormonal signalling system triggering metamorphosis in Drosophila melanogaster

Insect metamorphosis is triggered by the production, secretion and degradation of 20-hydroxyecdysone (ecdysone). In addition to its role in developmental regulation, increasing evidence suggests that ecdysone is involved in innate immunity processes, such as phagocytosis and the induction of antimic...

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Veröffentlicht in:	PLoS genetics 2021-11, Vol.17 (11), p.e1009916-e1009916
Hauptverfasser:	Nunes, Catarina, Koyama, Takashi, Sucena, Élio
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antimicrobial peptides Antimicrobial Peptides - genetics Bacteria Biodegradation Biology and Life Sciences Cellular signal transduction Drosomycin Drosophila Drosophila melanogaster Drosophila melanogaster - genetics Drosophila melanogaster - growth & development Drosophila Proteins - genetics Ecdysone Ecdysone - genetics Ecdysterone - genetics Fat body Gene Expression Regulation, Developmental - genetics Genetic aspects Hormones Hypotheses Immune system Infections Innate immunity Insects Intercellular Signaling Peptides and Proteins - genetics Larva - genetics Larva - growth & development Medicine and Health Sciences Metamorphosis Metamorphosis, Biological - genetics Pathogens Phagocytosis Physiological aspects Pupa - genetics Pupa - growth & development Pupariation Regulation Research and Analysis Methods Signal Transduction - genetics Steroids
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