Anaerobic peroxisomes in Entamoeba histolytica metabolize myo-inositol

Entamoeba histolytica is believed to be devoid of peroxisomes, like most anaerobic protists. In this work, we provided the first evidence that peroxisomes are present in E. histolytica, although only seven proteins responsible for peroxisome biogenesis (peroxins) were identified (Pex1, Pex6, Pex5, P...

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Veröffentlicht in:	PLoS pathogens 2021-11, Vol.17 (11), p.e1010041-e1010041
Hauptverfasser:	Verner, Zdeněk, Žárský, Vojtěch, Le, Tien, Narayanasamy, Ravi Kumar, Rada, Petr, Rozbeský, Daniel, Makki, Abhijith, Belišová, Darja, Hrdý, Ivan, Vancová, Marie, Lender, Corinna, König, Constantin, Bruchhaus, Iris, Tachezy, Jan
Format:	Artikel
Sprache:	eng
Schlagworte:	Affinity Anaerobes Anaerobiosis Analysis Antiparasitic agents Bacterial proteins Biology and Life Sciences Biosynthesis Chemical properties Datasets Drug development Endoplasmic reticulum Endosomes Entamoeba histolytica Entamoeba histolytica - metabolism Enzymes Glucose Identification and classification Immunoelectron microscopy Immunofluorescence Inositol Inositol - metabolism Inositols Localization Metabolism Microscopy Mitochondria Mutation NAD Pelomyxa Peroxins - metabolism Peroxisomal Targeting Signals Peroxisomes Peroxisomes - metabolism Phylogeny Proteins Proteomics Protozoan Proteins - genetics Protozoan Proteins - metabolism Receptors Substrates Vesicles
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