In vitro co-metabolism of epigallocatechin-3-gallate (EGCG) by the mucin-degrading bacterium Akkermansia muciniphila

Akkermansia muciniphila is a Gram-negative bacterium that resides within the gut mucus layer, and plays an important role in promoting gut barrier integrity, modulating the immune response and inhibiting gut inflammation. Growth stimulation of A. muciniphila by polyphenols including epigallocatechin...

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Veröffentlicht in:	PloS one 2021-12, Vol.16 (12), p.e0260757-e0260757
Hauptverfasser:	Xia, Yun, Zhang, Xuxiang, Jiang, Mingxin, Zhang, Hongbo, Wang, Yinfeng, Zhang, Yuyu, Seviour, Robert, Kong, Yunhong
Format:	Artikel
Sprache:	eng
Schlagworte:	Acids Akkermansia - growth & development Akkermansia - metabolism Akkermansia muciniphila Alzheimer's disease Amino acids Analysis Bacteria Biology and Life Sciences Carbon Catechin Catechin - analogs & derivatives Catechin - metabolism Diabetes Epicatechin Epigallocatechin gallate Gallic acid Glucose Glucose - metabolism Gram-negative bacteria Health aspects Immune response In Vitro Techniques Life sciences Medicine and Health Sciences Metabolic disorders Metabolism Metabolome Metabolomics Microbiota Mucin Mucins - metabolism Mucus Physical Sciences Polyphenols Protein sources Salts Substrates Trace elements
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