Genomic characterization of non-schistosomiasis-related squamous cell carcinoma of the urinary bladder: A retrospective exploratory study

Non-schistosomiasis related-squamous cell carcinoma of urinary bladder (NSR-SCCUB) is a rare tumor subtype distinct from urothelial carcinoma (UC). Studies assessing molecular biomarkers in bladder cancer have generally focused on UC, and genomic data of NSR-SCCUB is limited. We aim to provide addit...

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Veröffentlicht in:	PloS one 2021-12, Vol.16 (12), p.e0259272-e0259272
Hauptverfasser:	Al-Ezzi, Esmail M, Veitch, Zachary W, Salah, Samer H, Van der Kwast, Theodorus H, Stockley, Tracy L, Selvarajah, Shamini, Zhang, Tong, Sridhar, Srikala S, Sacher, Adrian G, Fallah-Rad, Nazanin, Kulkarni, Girish S, Zlotta, Alexandre R, Finelli, Antonio, Hansen, Aaron R
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Anticancer properties Antitumor agents Biology and Life Sciences Biomarkers Biomarkers, Tumor - genetics Bladder Bladder cancer Cancer therapies Carcinoma, Squamous Cell - genetics Carcinoma, Squamous Cell - pathology Cdc4 protein Chemotherapy Class I Phosphatidylinositol 3-Kinases - genetics Conflicts of interest CREB-Binding Protein - genetics Cyclin D1 - genetics Data collection Demographics Demography ErbB Receptors - genetics F-Box-WD Repeat-Containing Protein 7 - genetics Female Fibroblast growth factor receptors Genetic aspects Genomics Health care networks Hematology Humans Invasiveness Lymph nodes Lymphatic system Male Medical laboratories Medicine and Health Sciences Middle Aged Muscles Mutation Nucleotides Oncology p53 Protein Pathology Physiological aspects PTEN Phosphohydrolase - genetics PTEN protein Radiation therapy Receptor, Fibroblast Growth Factor, Type 3 - genetics Schistosomiasis Squamous cell carcinoma Survival Telomerase - genetics Tumor Suppressor Protein p53 - genetics Tumors Urinary bladder Urinary Bladder Neoplasms - genetics Urinary Bladder Neoplasms - pathology Urothelial carcinoma
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