Nanopore metagenomic sequencing for detection and characterization of SARS-CoV-2 in clinical samples

Objectives The COVID-19 pandemic has underscored the need for rapid novel diagnostic strategies. Metagenomic Next-Generation Sequencing (mNGS) may allow for the detection of pathogens that can be missed in targeted assays. The goal of this study was to assess the performance of nanopore-based Sequen...

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Veröffentlicht in:	PloS one 2021-11, Vol.16 (11), p.e0259712-e0259712
Hauptverfasser:	Gauthier, Nick P. G, Nelson, Cassidy, Bonsall, Michael B, Locher, Kerstin, Charles, Marthe, MacDonald, Clayton, Krajden, Mel, Chorlton, Samuel D, Manges, Amee R
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Assaying Bioinformatics Biology and life sciences Coronaviruses COVID-19 Crosstalk Diagnostic systems Disease control DNA sequencing Genomes Hospitals Infections Laboratories Medicine Medicine and health sciences Metagenomics Methods Next-generation sequencing Nucleotide sequencing Pandemics Pathogens Pathology Performance assessment Phylogeny Polymerase chain reaction Public health Research and Analysis Methods RNA polymerase Severe acute respiratory syndrome Severe acute respiratory syndrome coronavirus 2 Supervision Viral diseases Viral infections Viruses Zoology
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